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Cardiovascular and metabolic drugs

Implitapide

Also known as implitapida, (2S)-2-cyclopentyl-2-(4-((2,4-dimethyl-9H-pyrido(2,3-b)indol-9-yl)methyl)phenyl)-N-((1S)-2-hydroxy-1-phenylethyl)ethanamide, implitapidum

CAS 177469-96-4Formula C35H37N3O2Molar mass 531.70 g/mol
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Implitapide chemical structure, C35H37N3O2, CAS 177469-96-4
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
177469-96-4
Formula
C35H37N3O2
Molar mass
531.70 g/mol
HS code
293399
Category
Cardiovascular and metabolic drugs

What is Implitapide?

Plain description, key identifiers and synonyms

Implitapide is a microsomal triglyceride transfer protein (MTP) inhibitor with antihyperlipidemic activity. In an animal model, inhibition of MTP by implitapide reduced both total cholesterol and triglyceride levels and suppressed progression of atherosclerotic lesions.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(2S)-2-cyclopentyl-2-[3-[(2,4-dimethylpyrido[2,3-b]indol-9-yl)methyl]phenyl]-N-[(1R)-2-hydroxy-1-phenylethyl]acetamide
CAS number
177469-96-4 CAS number cross-checked
Molecular formula
C35H37N3O2
UNII
Q70OH404HR
InChIKey
AMNXBQPRODZJQR-DITALETJSA-N
InChI
InChI=1S/C35H37N3O2/c1-23-19-24(2)36-34-32(23)29-17-8-9-18-31(29)38(34)21-25-11-10-16-28(20-25)33(27-14-6-7-15-27)35(40)37-30(22-39)26-12-4-3-5-13-26/h3-5,8-13,16-20,27,30,33,39H,6-7,14-15,21-22H2,1-2H3,(H,37,40)/t30-,33-/m0/s1
Canonical SMILES
Cc1cc(C)c2c3ccccc3n(Cc3cccc(C(C(=O)NC(CO)c4ccccc4)C4CCCC4)c3)c2n1
Isomeric SMILES
CC1=CC(=NC2=C1C3=CC=CC=C3N2CC4=CC(=CC=C4)[C@H](C5CCCC5)C(=O)N[C@@H](CO)C6=CC=CC=C6)C

Synonyms

  • implitapida
  • (2S)-2-cyclopentyl-2-(4-((2,4-dimethyl-9H-pyrido(2,3-b)indol-9-yl)methyl)phenyl)-N-((1S)-2-hydroxy-1-phenylethyl)ethanamide
  • implitapidum
  • (2S)-2-cyclopentyl-2-(3-((2,4-dimethyl-9H-pyrido(2,3-b)indol-9-yl)methyl)phenyl)-N-((1R)-2-hydroxy-1-phenylethyl)acetamide
  • (2S)-2-Cyclopentyl-2-{3-[(2,4-dimethyl-9H-pyrido[2,3-b]indol-9-yl)methyl]phenyl}-N-[(1R)-2-hydroxy-1-phenylethyl]acetamide
  • (2S)-2-cyclopentyl-2-[3-[(2,4-dimethylpyrido[2,3-b]indol-9-yl)methyl]phenyl]-N-[(1R)-2-hydroxy-1-phenylethyl]acetamide
  • (2S)-2-cyclopentyl-2-[4-[(2,4-dimethylpyrido[2,3-b]indol-9-yl)methyl]phenyl]-N-[(1R)-2-hydroxy-1-phenylethyl]acetamide
  • (.Alpha.s)-alpha-(alpha-(2,4-dimethyl-9H-pyrido(2,3-b)indol-9-yl)-p-tolyl)-N-((.alpha.r)-alpha-(hydroxymethyl)benzyl)cyclopentaneacetamide
  • (alphaS)-alpha-(alpha-(2,4-Dimethyl-9H-pyrido(2,3-b)indol-9-yl)-p-tolyl)-N-((alphaR)-alpha-(hydroxymethyl)benzyl)cyclopentaneacetamide
  • (alphaS)-alpha-(alpha-(2,4-Dimethyl-9H-pyrido(2,3-b)indol-9-yl)-p-tolyl)-N-((alphaR)-alpha-(hydroxymethyl)benzyl)cyclopentaneacetamide.

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
531.70 g/molcalc.
Exact mass
531.2886 Dacalc.
LogP (octanol/water)
6.98calc.
Topological polar surface area
67.15 Ųcalc.
Hydrogen bond donors
2calc.
Hydrogen bond acceptors
3calc.
Rotatable bonds
8calc.
Heavy atoms
40calc.
Rings
6calc.
Aromatic rings
5calc.
Fraction sp3 carbons
0.31calc.
Formal charge
0calc.
Stereocentres
2calc.
Lipinski rule of five
Fails (2 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C(NCc1ccccc1)C(c1cccc(Cn2c3ccccc3c3cccnc32)c1)C1CCCC1

O=C(NCc1ccccc1)C(c1cccc(Cn2c3ccccc3c3cccnc32)c1)C1CCCC1

6 rings, 36 atoms.

1 other chemical share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Implitapide suppliers

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Implitapide price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Roles

  • anticholesteremic drug
  • antilipemic drug
  • pharmaceutical

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Implitapide is traded under.

HS 2933.99Indicative HS code

Heterocyclic compounds with nitrogen hetero-atom(s) only, other

World exports in 2024
$12.1B
−31.0% vs 2023, imports $28.8B
2019 to 2024
Top exporters
  1. China30.5%
  2. India * partner reported16.3%
  3. Ireland9.0%
Top importers
  1. Slovenia31.7%
  2. Italy24.2%
  3. United States5.0%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Implitapide is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Implitapide, based on the data on this page

What is Implitapide?

Implitapide is a microsomal triglyceride transfer protein (MTP) inhibitor with antihyperlipidemic activity. In an animal model, inhibition of MTP by implitapide reduced both total cholesterol and triglyceride levels and suppressed progression of atherosclerotic lesions.

What is the CAS number of Implitapide?

The CAS registry number of Implitapide is 177469-96-4.

What is the molecular formula and weight of Implitapide?

The molecular formula of Implitapide is C35H37N3O2 and its molar mass is 531.70 g/mol.

What is Implitapide used for?

Known uses and roles of Implitapide include cardiovascular drugs in pharmaceuticals, anticholesteremic drug, antilipemic drug and pharmaceutical.

Is Implitapide hazardous?

No GHS hazard classification for Implitapide is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Implitapide?

Implitapide is usually classified under HS code 293399 (Heterocyclic compounds with nitrogen hetero-atom(s) only, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Implitapide?

Post a free request on CompoundList and suppliers of Implitapide will send you quotes. Your contact details stay private until you accept a quote.

What is the price of Implitapide?

Suppliers quote Implitapide on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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