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Amines and amides

Iodoacetamide

Also known as 2-Iodoacetamide, Surauto, Acetamide, 2-iodo-

CAS 144-48-9Formula C2H4INOMolar mass 184.96 g/molEC 205-630-1
GHS signal word: Danger. Pictograms: Acute toxicity (severe), Harmful or irritant, Serious health hazard 93 suppliers listed
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Iodoacetamide chemical structure, C2H4INO, CAS 144-48-9
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
144-48-9
Formula
C2H4INO
Molar mass
184.96 g/mol
EC number
205-630-1
HS code
292419
Category
Amines and amides

What is Iodoacetamide?

Plain description, key identifiers and synonyms

Iodoacetamide is a sulfhydryl alkylating reagent that forms covalent bonds with the thiol group of cysteines so the protein or peptide no longer forms disulfide bonds.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
2-iodoacetamide
CAS number
144-48-9 CAS number cross-checked
EC number
205-630-1
Molecular formula
C2H4INO
UNII
ZRH8M27S79
MDL number
MFCD00008028
InChIKey
PGLTVOMIXTUURA-UHFFFAOYSA-N
InChI
InChI=1S/C2H4INO/c3-1-2(4)5/h1H2,(H2,4,5)
SMILES (canonical and isomeric)
C(C(=O)N)I

Synonyms

  • 2-Iodoacetamide
  • Surauto
  • Acetamide, 2-iodo-
  • Monoiodoacetamide
  • N-(3-Methoxy-4-butoxybenzyl)thiobarbituric acid
  • USAF D-1
  • alpha-Iodoacetamide
  • 2-Iodo-acetamide
  • deltop
  • iodacetamide
  • iodoacetoamide
  • a-iodoacetamide
  • iodo acetamide
  • 2-iodo-acetamid
  • Iodoacetamide acid
  • Deltop, Iodoacetamide, Monoiodoacetamide, NSC 9581, Surauto, alpha-Iodoacetamide
  • Alpha-iodo acetamide
  • Iodoacetamide, IA, IAM
  • Iodoacetamide, BioUltra
  • 2-Iodoacetamide, 98%
  • Acetamide, iodo- (6CI)
  • 4-02-00-00536 (Beilstein Handbook Reference)
  • Pgltvomixtuura-uhfffaoysa-
  • Acetamide, 2-iodo- (8CI,9CI)
  • Sdccgsbi-0050552.p002
Show all 30 synonyms
  • Iodoacetamide, >=98.0% (AT), purum
  • Iodoacetamide, Single use vial of 56 mg
  • Iodoacetamide, >=99% (NMR), crystalline
  • Iodoacetamide, Vetec(TM) reagent grade, 99%
  • 2-Iodoacetamide Solution in Methanol, 1000ug/mL

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
184.96 g/molcalc.
Exact mass
184.9338 Dacalc.
LogP (octanol/water)
-0.09calc.
Topological polar surface area
43.09 Ųcalc.
Hydrogen bond donors
1calc.
Hydrogen bond acceptors
1calc.
Rotatable bonds
1calc.
Heavy atoms
5calc.
Rings
0calc.
Aromatic rings
0calc.
Fraction sp3 carbons
0.5calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS06: Acute toxicity (severe)
Acute toxicity (severe)
GHS07: Harmful or irritant
Harmful or irritant
GHS08: Serious health hazard
Serious health hazard

Hazard statements

  • H301Toxic if swallowed.
  • H317May cause an allergic skin reaction.
  • H334May cause allergy or asthma symptoms or breathing difficulties if inhaled.
  • H413May cause long lasting harmful effects to aquatic life.
Precautionary statements (21)
  • P233Keep container tightly closed.
  • P260Do not breathe dust, fume, gas, mist, vapours or spray.
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P270Do not eat, drink or smoke when using this product.
  • P271Use only outdoors or in a well-ventilated area.
  • P272Contaminated work clothing should not be allowed out of the workplace.
  • P273Avoid release to the environment.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P284In case of inadequate ventilation wear respiratory protection.
  • P301 + P316If swallowed: Get emergency medical help immediately.
  • P302 + P352If on skin: Wash with plenty of water.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P330Rinse mouth.
  • P333 + P317If skin irritation or rash occurs: Get medical help.
  • P342 + P316If experiencing respiratory symptoms: Get emergency medical help immediately.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P403Store in a well-ventilated place.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Iodoacetamide suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 93 suppliers
30 of 30 offers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

93 suppliers in 13 countries

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Iodoacetamide price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

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Uses and applications

What the substance is used for, by industry and function

Pharmacological actions

  • Alkylating Agents
  • Enzyme Inhibitors

Regulatory status

Inventories, regulations and trade controls that list this substance

United States

  • TSCA inventory (USA)
    Status: Active in US commerce

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Iodoacetamide is traded under.

HS 2924.19Indicative HS code

Acyclic amides (including acyclic carbamates) and their derivatives, salts thereof, other

World exports in 2024
$2.38B
−1.7% vs 2023, imports $2.22B
2019 to 2024
Top exporters
  1. China34.7%
  2. Germany12.5%
  3. India * partner reported6.8%
Top importers
  1. United States17.5%
  2. Germany8.8%
  3. India * partner reported6.7%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Iodoacetamide is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Iodoacetamide, based on the data on this page

What is Iodoacetamide?

Iodoacetamide is a sulfhydryl alkylating reagent that forms covalent bonds with the thiol group of cysteines so the protein or peptide no longer forms disulfide bonds.

What is the CAS number of Iodoacetamide?

The CAS registry number of Iodoacetamide is 144-48-9.

What is the molecular formula and weight of Iodoacetamide?

The molecular formula of Iodoacetamide is C2H4INO and its molar mass is 184.96 g/mol.

What is Iodoacetamide used for?

Known uses and roles of Iodoacetamide include biochemical and pharmacological tools in research and laboratory, alkylating agents and enzyme inhibitors.

Is Iodoacetamide hazardous?

Iodoacetamide carries the GHS signal word "Danger". Main hazards: toxic if swallowed, may cause an allergic skin reaction, may cause allergy or asthma symptoms or breathing difficulties if inhaled. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Iodoacetamide?

Iodoacetamide is usually classified under HS code 292419 (Acyclic amides (including acyclic carbamates) and their derivatives, salts thereof, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Iodoacetamide?

CompoundList lists 93 suppliers of Iodoacetamide in China, United States, Germany, United Kingdom and 9 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Iodoacetamide?

Suppliers quote Iodoacetamide on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Iodoacetamide

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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