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Key facts

What buyers check first

CAS number
71827-03-7
Formula
C48H74O14
Molar mass
875.11 g/mol
EC number
276-046-2
HS code
293220
Category
Impurities and reference standards

What is Ivermectin B1a?

Plain description, key identifiers and synonyms

LSM-5397 is a milbemycin.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(1R,4S,5'S,6R,6'R,8R,10E,12S,13S,14E,16E,20R,21R,24S)-6'-[(2S)-butan-2-yl]-21,24-dihydroxy-12-[(2R,4S,5S,6S)-5-[(2S,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy-4-methoxy-6-methyloxan-2-yl]oxy-5',11,13,22-tetramethylspiro[3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene-6,2'-oxane]-2-one
CAS number
71827-03-7 CAS number cross-checkedOther or deprecated CAS: 70161-11-4
EC numbers
276-046-2, 615-075-0
Molecular formula
C48H74O14
UNII
91Y2202OUW
InChIKey
AZSNMRSAGSSBNP-XPNPUAGNSA-N
InChI
InChI=1S/C48H74O14/c1-11-25(2)43-28(5)17-18-47(62-43)23-34-20-33(61-47)16-15-27(4)42(26(3)13-12-14-32-24-55-45-40(49)29(6)19-35(46(51)58-34)48(32,45)52)59-39-22-37(54-10)44(31(8)57-39)60-38-21-36(53-9)41(50)30(7)56-38/h12-15,19,25-26,28,30-31,33-45,49-50,52H,11,16-18,20-24H2,1-10H3/b13-12+,27-15+,32-14+/t25-,26-,28-,30-,31-,33+,34-,35-,36-,37-,38-,39-,40+,41-,42-,43+,44-,45+,47+,48+/m0/s1
Canonical SMILES
CCC(C)C1OC2(CCC1C)CC1CC(CC=C(C)C(OC3CC(OC)C(OC4CC(OC)C(O)C(C)O4)C(C)O3)C(C)C=CC=C3COC4C(O)C(C)=CC(C(=O)O1)C34O)O2
Isomeric SMILES
CC[C@H](C)[C@@H]1[C@H](CC[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(/[C@H]([C@H](/C=C/C=C/4\CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O)OC)OC)\C)C

Synonyms

  • Dihydroavermectin B1a
  • 22,23-Dihydroavermectin B1a
  • avermectin H2B1a
  • 5-O-demethyl-22,23-dihydroavermectin A1a
  • H2B1a
  • Avermectin A1a, 5-O-demethyl-22,23-dihydro-
  • Ivermectin Component B1a
  • Ivermectin B1a-d2
  • Ivermectin B1a (>85%)
  • Hyvermectin,
  • Mectizan,
  • Eqvalan,
  • Ivomec,
  • Ivermectin (IVM)
  • IVM
  • dihydro avermectin Bla
  • Ivermectin Impurity 39
  • Ivermectin (MK-0933)
  • Ivermectin - Bio-X trade mark
  • 71827-03-7 (Unlabelled)
  • Spiro[11,15-methano-2H,13H,17H-furo[4,3,2-pq][2,6]benzodioxacyclooctadecin-13,2'-[2H]pyran], Avermectin A1a Deriv.
  • 5-O-demethyl-22,23-dihydro-avermectin A1a
  • 22,23-Dihydroavermectin b1a, ivermectin
  • 5-O-Demethyl-22,23-dihydro-avermectin A1a-D2
  • Avermectin A1a, 22,23-dihydro-5-O-demethyl-
Show all 34 synonyms
  • Ivermectin, British Pharmacopoeia (BP) Reference Standard
  • Ivermectin, European Pharmacopoeia (EP) Reference Standard
  • Ivermectin, United States Pharmacopeia (USP) Reference Standard
  • oxan-2-yl]oxy}-5,11',13',22'-tetramethyl-3',7',19'-trio
  • Ivermectin, Pharmaceutical Secondary Standard, Certified Reference Material
  • (2aE,4E,5'S,6S,6'R,7S,8E,11R,13R,15S,17aR,20R,20aR,20bS)-6'-[(2S)-butan-2-yl]-20,20b-dihydroxy-5',6,8,19-tetramethyl-17
  • oxo-3',4',5',6,6',10,11,14,15,17,17a,20,20a,20b-tetradecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacy
  • clooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-alpha-L-arabino-hexopyranosyl)-3-O-methyl-alpha-L-arabino-hexopyranoside
  • xaspiro[oxane-2,6'-tetracyclo[15.6.1.1^{4,8}.0^{20,24}]pentacosane]-10',14',16',22'-tetraen-2'-one

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
875.11 g/molcalc.
Exact mass
874.5079 Dacalc.
LogP (octanol/water)
5.6calc.
Topological polar surface area
170.1 Ųcalc.
Hydrogen bond donors
3calc.
Hydrogen bond acceptors
14calc.
Rotatable bonds
8calc.
Heavy atoms
62calc.
Rings
7calc.
Aromatic rings
0calc.
Fraction sp3 carbons
0.81calc.
Formal charge
0calc.
Stereocentres
20calc.
Lipinski rule of five
Fails (3 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C1OC2CC(CC=CC(OC3CCC(OC4CCCCO4)CO3)CC=CC=C3COC4CC=CC1C34)OC1(CCCCO1)C2

O=C1OC2CC(CC=CC(OC3CCC(OC4CCCCO4)CO3)CC=CC=C3COC4CC=CC1C34)OC1(CCCCO1)C2

7 rings, 45 atoms.

35 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS06: Acute toxicity (severe)
Acute toxicity (severe)
GHS07: Harmful or irritant
Harmful or irritant
GHS08: Serious health hazard
Serious health hazard
GHS09: Hazardous to the environment
Hazardous to the environment

Hazard statements

  • H300Fatal if swallowed.
  • H312Harmful in contact with skin.
  • H361Suspected of damaging fertility or the unborn child.
  • H373May cause damage to organs through prolonged or repeated exposure.
  • H400Very toxic to aquatic life.
Precautionary statements (17)
  • P203Obtain, read and follow all safety instructions before use.
  • P260Do not breathe dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P270Do not eat, drink or smoke when using this product.
  • P273Avoid release to the environment.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P301 + P316If swallowed: Get emergency medical help immediately.
  • P302 + P352If on skin: Wash with plenty of water.
  • P317Get medical help.
  • P318If exposed or concerned, get medical advice.
  • P319Get medical help if you feel unwell.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P330Rinse mouth.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P391Collect spillage.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Ivermectin B1a suppliers

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Ivermectin B1a price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Applications are not documented for this substance yet. Suppliers often describe uses on their product pages, linked in the suppliers list above.

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Ivermectin B1a is traded under.

HS 2932.20Indicative HS code

Lactones

World exports in 2024
$1.97B
−4.7% vs 2023, imports $2.07B
2019 to 2024
Top exporters
  1. China56.3%
  2. India * partner reported7.4%
  3. Germany7.3%
Top importers
  1. United States14.2%
  2. India * partner reported13.5%
  3. Brazil8.5%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Ivermectin B1a is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Ivermectin B1a, based on the data on this page

What is Ivermectin B1a?

LSM-5397 is a milbemycin.

What is the CAS number of Ivermectin B1a?

The CAS registry number of Ivermectin B1a is 71827-03-7. Other or deprecated CAS numbers: 70161-11-4.

What is the molecular formula and weight of Ivermectin B1a?

The molecular formula of Ivermectin B1a is C48H74O14 and its molar mass is 875.11 g/mol.

Is Ivermectin B1a hazardous?

Ivermectin B1a carries the GHS signal word "Danger". Main hazards: fatal if swallowed, harmful in contact with skin, suspected of damaging fertility or the unborn child. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Ivermectin B1a?

Ivermectin B1a is usually classified under HS code 293220 (Lactones). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Ivermectin B1a?

CompoundList lists 45 suppliers of Ivermectin B1a in United States, China, United Kingdom, Germany and 6 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Ivermectin B1a?

Suppliers quote Ivermectin B1a on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Ivermectin B1a

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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