CompoundList
Sign in
Central nervous system drugs

Ketamine

Also known as dl-Ketamine, Ketaject, Special K

CAS 6740-88-1Formula C13H16ClNOMolar mass 237.73 g/molEC 229-804-1
GHS signal word: Warning. Pictograms: Harmful or irritant Prohibited, not for trade Drug substance
Why it is not for trade
Ketamine chemical structure, C13H16ClNO, CAS 6740-88-1
2D chemical structure

Key facts

What buyers check first

All properties
Appearance
Crystals from pentane-ether
Melting point
92.5 °C
Solubility
White crystals, mp 262-263 °C. Solubility in water: 20 g/100mL. Freely soluble in methan…
HS code
292239
Category
Central nervous system drugs

What is Ketamine?

Plain description, key identifiers and synonyms

Ketamine is a member of the class of cyclohexanones in which one of the hydrogens at position 2 is substituted by a 2-chlorophenyl group, while the other is substituted by a methylamino group. It has a role as an analgesic, a xenobiotic, an intravenous anaesthetic, a neurotoxin, a NMDA receptor antagonist and an environmental contaminant. It is a member of cyclohexanones, a secondary amino compound and a member of monochlorobenzenes. It is functionally related to a norketamine.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
2-(2-chlorophenyl)-2-(methylamino)cyclohexan-1-one
CAS number
6740-88-1 CAS number cross-checkedOther or deprecated CAS: 100477-72-3
EC number
229-804-1
Molecular formula
C13H16ClNO
UNII
690G0D6V8H
InChIKey
YQEZLKZALYSWHR-UHFFFAOYSA-N
InChI
InChI=1S/C13H16ClNO/c1-15-13(9-5-4-8-12(13)16)10-6-2-3-7-11(10)14/h2-3,6-7,15H,4-5,8-9H2,1H3
SMILES (canonical and isomeric)
CNC1(CCCCC1=O)C2=CC=CC=C2Cl

Synonyms

  • dl-Ketamine
  • Ketaject
  • Special K
  • (+-)-Ketamine
  • CI 581 base
  • Ketaminum
  • CLSTA 20
  • Calypsol
  • narketan
  • Cetamina
  • Tekam
  • ketamina
  • 2-(Methylamino)-2-(2-chlorophenyl)cyclohexanone
  • Ursotamin
  • Vetaket
  • Anaket v
  • 2-(o-Chlorophenyl)-2-(methylamino)-cyclohexanone
  • Special K [street name]
  • 2-(2-chlorophenyl)-2-(methylamino)cyclohexan-1-one
  • Clorketam 1000
  • Ketasol 100
  • 2-(2-Chlorophenyl)-2-(methylamino)cyclohexanone
  • Imalgene 1000
  • cyclohexanone, 2-(2-chlorophenyl)-2-(methylamino)-
  • Cyclohexanone, 2-(o-chlorophenyl)-2-(methylamino)-, (+-)-
Show all 38 synonyms
  • Ketafol component ketamine
  • 2-(2-Chloro-phenyl)-2-methylamino-cyclohexanone
  • Cyclohexanone, 2-(2-chlorophenyl)-2-(methylamino)-, (+-)-
  • Special K (street name)
  • Ketalar
  • Ketalar base
  • (+/-)-Ketamine
  • Ketanest
  • Ketolar
  • Ketamine (INN)
  • 2-(o-Chlorophenyl)-2-(methylamino)cyclohexanone
  • Cyclohexanone, 2-(o-chlorophenyl)-2-(methylamino)-
  • (+/-)-2-(o-Chlorophenyl)-2-(methylamino)cyclohexanone

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
Crystals from pentane-etherexp.
Melting point
92.5 °Cexp.
Solubility
White crystals, mp 262-263 °C. Solubility in water: 20 g/100mL. Freely soluble in methanol, soluble in alcohol, sparingly soluble in chloroform /Ketamine hydrochloride/exp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
237.73 g/molcalc.
Exact mass
237.092 Dacalc.
LogP (octanol/water)
2.9calc.
Topological polar surface area
29.1 Ųcalc.
Hydrogen bond donors
1calc.
Hydrogen bond acceptors
2calc.
Rotatable bonds
2calc.
Heavy atoms
16calc.
Rings
2calc.
Aromatic rings
1calc.
Fraction sp3 carbons
0.46calc.
Formal charge
0calc.
Stereocentres
1calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C1CCCCC1c1ccccc1

O=C1CCCCC1c1ccccc1

2 rings, 13 atoms, the 2-Phenylcyclohexanone ring system.

222 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant

Hazard statements

  • H302 + H332Harmful if swallowed. Harmful if inhaled.
  • H302Harmful if swallowed.
  • H332Harmful if inhaled.
Precautionary statements (9)
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P270Do not eat, drink or smoke when using this product.
  • P271Use only outdoors or in a well-ventilated area.
  • P301 + P317If swallowed: Get medical help.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P317Get medical help.
  • P330Rinse mouth.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Ketamine suppliers

Trading restrictions apply to this substance

Psychotropic substance

Ketamine is prohibited on CompoundList. Listings, quotes and messages are disabled. This page is kept for information only.

Listing and enquiries are not allowed for this substance.

Reference: India NDPS Act notified psychotropic substance

Our policy on controlled substances

Ketamine price

Indicative price range per kg from live supplier offers

Prices are not shown for prohibited substances.

Uses and applications

What the substance is used for, by industry and function

Ketamine, its salts, isomers, and salts of isomers (DEA Code Number: 7285) is a Schedule III controlled substance.

Schedule III Controlled Substance: (A) The drug or other substance has a potential for abuse less than the drugs or other substances in schedules I and II. (B) The drug or other substance has a currently accepted medical use in treatment in the United States. (C) Abuse of the drug or other substance may lead to moderate or low physical dependence or high psychological dependence.

Analgesics, Anesthetics, Dissociative, Excitatory Amino Acid Antagonists.

Veterinary medication:.

Use classes: Pharmaceuticals.

Pharmacological actions

  • Analgesics
  • Anesthetics, Dissociative
  • Excitatory Amino Acid Antagonists

Roles

  • NMDA receptor antagonist
  • anaesthetic
  • analgesic
  • anti-anaemic agent
  • anti-obesity agent
  • anticonvulsant
  • antidepressant
  • antidyskinesia agent
  • antineoplastic agent
  • antiparkinson drug
  • antipsychotic agent
  • antiviral agent
  • anxiolytic drug
  • cardiovascular drug
  • environmental contaminant
  • immunomodulator
  • immunosuppressive agent
  • intravenous anaesthetic
  • neuroprotective agent
  • neurotoxin
  • ophthalmology drug
  • pharmaceutical
  • vulnerary
  • xenobiotic

Functional uses

  • Pharmaceutical

Pharmacology

Ketamine is a General Anesthetic. The physiologic effect of ketamine is by means of General Anesthesia.

How it is made

Preparation: C.L. Stevens, Belgium patent 634208, idem, United States of America patent 3254124 (1963, 1966 both to Parke, Davis).

Prepared by bromination of o-chlorophenyl cyclopentyl ketone, which is then reacted with methylamine to give the methylimino alcohol. Thermolysis of the imino hydrochloride yields ketamine by ring expansion.

Regulatory status

Inventories, regulations and trade controls that list this substance

Psychotropic substance

Ketamine is prohibited on CompoundList. Listings, quotes and messages are disabled. This page is kept for information only.

Listing and enquiries are not allowed for this substance.

Reference: India NDPS Act notified psychotropic substance

Our policy on controlled substances

Health and food

  • Active ingredient in FDA approved drug labels

Controls

  • Controlled psychotropic substance

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Ketamine is traded under.

HS 2922.39Indicative HS code

Amino-aldehydes, amino-ketones and amino-quinones, other than those containing more than…

World exports in 2024
$187M
−0.3% vs 2023, imports $159M
2019 to 2024
Top exporters
  1. China35.3%
  2. India * partner reported27.7%
  3. Germany12.7%
Top importers
  1. Germany17.3%
  2. United States13.8%
  3. India * partner reported9.9%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Ketamine is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Ketamine, based on the data on this page

What is Ketamine?

Ketamine is a member of the class of cyclohexanones in which one of the hydrogens at position 2 is substituted by a 2-chlorophenyl group, while the other is substituted by a methylamino group.

What is the CAS number of Ketamine?

The CAS registry number of Ketamine is 6740-88-1. Other or deprecated CAS numbers: 100477-72-3.

What is the molecular formula and weight of Ketamine?

The molecular formula of Ketamine is C13H16ClNO and its molar mass is 237.73 g/mol.

What is Ketamine used for?

Ketamine, its salts, isomers, and salts of isomers (DEA Code Number: 7285) is a Schedule III controlled substance. Schedule III Controlled Substance: (A) The drug or other substance has a potential for abuse less than the drugs or other substances in schedules I and II.

Is Ketamine hazardous?

Ketamine carries the GHS signal word "Warning". Main hazards: harmful if swallowed. harmful if inhaled, harmful if swallowed, harmful if inhaled. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Ketamine?

Ketamine is usually classified under HS code 292239 (Amino-aldehydes, amino-ketones and amino-quinones, other than those containing more than…). This is indicative, confirm it with your customs broker before shipping.

Can I buy Ketamine on CompoundList?

No. Ketamine is on our prohibited list, so listings, quotes and messages for it are disabled. This page is kept for information only.

Guides for buyers

Practical guides that help when you source, ship or handle Ketamine

Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page

Explore more in Central nervous system drugs or HS code 292239

Not available for trade
Why