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Antibiotics and anti-infectives

Knipholone

Also known as 1-(3-acetyl-2,6-dihydroxy-4-methoxyphenyl)-4,5-dihydroxy-2-methylanthracene-9,10-dione, 1-(3-acetyl-2,6-dihydroxy-4-methoxyphenyl)-4,6-dihydroxy-2-methylanthracene-9,10-dione, 1-(3-acetyl-2,6-dihydroxy-4-methoxyphenyl)-4,5-dihydroxy-2-methylanthra-9,10-quinone

CAS 94450-08-5Formula C24H18O8Molar mass 434.40 g/mol
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Knipholone chemical structure, C24H18O8, CAS 94450-08-5
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
94450-08-5
Formula
C24H18O8
Molar mass
434.40 g/mol
HS code
291469
Category
Antibiotics and anti-infectives

What is Knipholone?

Plain description, key identifiers and synonyms

Knipholone is an anthraquinone that is anthracene-9,10-dione substituted by hydroxy groups at positions 4 and 6, a methyl group at position 2 and a 3-acetyl-2,6-dihydroxy-4-methoxyphenyl group at position 1. It exhibits antioxidant, cytotoxic and antiplasmodial activities. It has a role as an antioxidant, a metabolite, an antineoplastic agent, a leukotriene antagonist and an antiplasmodial drug. It is a polyphenol, a member of resorcinols, a dihydroxyanthraquinone, a member of methoxybenzenes, a methyl ketone and an aromatic ketone.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
1-(3-acetyl-2,6-dihydroxy-4-methoxyphenyl)-4,5-dihydroxy-2-methylanthracene-9,10-dione
CAS number
94450-08-5 CAS number cross-checked
Molecular formula
C24H18O8
InChIKey
DUENHQWYLVQDQK-UHFFFAOYSA-N
InChI
InChI=1S/C24H18O8/c1-9-7-13(27)20-21(22(29)11-5-4-6-12(26)18(11)24(20)31)16(9)19-14(28)8-15(32-3)17(10(2)25)23(19)30/h4-8,26-28,30H,1-3H3
SMILES (canonical and isomeric)
CC1=CC(=C2C(=C1C3=C(C(=C(C=C3O)OC)C(=O)C)O)C(=O)C4=C(C2=O)C(=CC=C4)O)O

Synonyms

  • 1-(3-acetyl-2,6-dihydroxy-4-methoxyphenyl)-4,5-dihydroxy-2-methylanthracene-9,10-dione
  • 1-(3-acetyl-2,6-dihydroxy-4-methoxyphenyl)-4,6-dihydroxy-2-methylanthracene-9,10-dione
  • 1-(3-acetyl-2,6-dihydroxy-4-methoxyphenyl)-4,5-dihydroxy-2-methylanthra-9,10-quinone

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
434.40 g/molcalc.
Exact mass
434.1002 Dacalc.
LogP (octanol/water)
3.47calc.
Topological polar surface area
141.4 Ųcalc.
Hydrogen bond donors
4calc.
Hydrogen bond acceptors
8calc.
Rotatable bonds
3calc.
Heavy atoms
32calc.
Rings
4calc.
Aromatic rings
3calc.
Fraction sp3 carbons
0.13calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C1c2ccccc2C(=O)c2c1cccc2-c1ccccc1

O=C1c2ccccc2C(=O)c2c1cccc2-c1ccccc1

4 rings, 22 atoms, the 9,10-Anthracenedione, 1-phenyl- ring system.

21 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Knipholone suppliers

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Knipholone price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Roles

  • antagonist
  • antiinfective agent
  • antimicrobial agent
  • antimicrobial drug
  • antineoplastic agent
  • antioxidant
  • antiparasitic agent
  • antiplasmodial drug
  • antiprotozoal drug
  • hormone antagonist
  • hormone receptor modulator
  • leukotriene antagonist
  • metabolite
  • pharmaceutical
  • receptor modulator

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Knipholone is traded under.

HS 2914.69Indicative HS code

Quinones, other

World exports in 2024
$162M
−10.1% vs 2023, imports $157M
2019 to 2024
Top exporters
  1. China32.8%
  2. Netherlands29.3%
  3. Japan13.8%
Top importers
  1. United States23.0%
  2. India * partner reported16.1%
  3. Thailand7.9%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Knipholone is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Knipholone, based on the data on this page

What is Knipholone?

Knipholone is an anthraquinone that is anthracene-9,10-dione substituted by hydroxy groups at positions 4 and 6, a methyl group at position 2 and a 3-acetyl-2,6-dihydroxy-4-methoxyphenyl group at position 1. It exhibits antioxidant, cytotoxic and antiplasmodial activities.

What is the CAS number of Knipholone?

The CAS registry number of Knipholone is 94450-08-5.

What is the molecular formula and weight of Knipholone?

The molecular formula of Knipholone is C24H18O8 and its molar mass is 434.40 g/mol.

What is Knipholone used for?

Known uses and roles of Knipholone include antagonist, antiinfective agent, antimicrobial agent, antimicrobial drug, antineoplastic agent and 10 more.

Is Knipholone hazardous?

No GHS hazard classification for Knipholone is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Knipholone?

Knipholone is usually classified under HS code 291469 (Quinones, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Knipholone?

Post a free request on CompoundList and suppliers of Knipholone will send you quotes. Your contact details stay private until you accept a quote.

What is the price of Knipholone?

Suppliers quote Knipholone on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Knipholone

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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