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L-Glutamine

Also known as glutamine, Levoglutamide, L-(+)-Glutamine

CAS 56-85-9Formula C5H10N2O3Molar mass 146.15 g/molEC 105-459-1
259 suppliers listed Drug substance
L-Glutamine chemical structure, C5H10N2O3, CAS 56-85-9
2D chemical structure

Key facts

What buyers check first

Appearance
White crystalline powder
Melting point
184 to 185
Density
1.364 g/cm³
Solubility
In water, 41,300 mg/L at 25 °C
HS code
292419
Category
Amino acids and derivatives
Illustrative photo, off-white crystalline powder in an HDPE jar on a laboratory bench
Typical packagingIllustrative packaging image, not the actual product

What is L-Glutamine?

Plain description, key identifiers and synonyms

L-glutamine is an optically active form of glutamine having L-configuration. It has a role as a micronutrient, a nutraceutical, an EC 1.14.13.39 (nitric oxide synthase) inhibitor, a mouse metabolite, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite and a human metabolite. It is a L-alpha-amino acid, a glutamine family amino acid, a glutamine and a proteinogenic amino acid. It is a conjugate base of a L-glutaminium. It is a conjugate acid of a L-glutaminate. It is an enantiomer of a D-glutamine. It is a tautomer of a L-glutamine zwitterion.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(2S)-2,5-diamino-5-oxopentanoic acid
CAS number
56-85-9 CAS number cross-checkedOther or deprecated CAS: 6899-04-3
EC numbers
105-459-1, 200-292-1, 230-006-0
Molecular formula
C5H10N2O3
UNII
0RH81L854J
MDL number
MFCD00008044
INCI name
GLUTAMINE
InChIKey
ZDXPYRJPNDTMRX-VKHMYHEASA-N
InChI
InChI=1S/C5H10N2O3/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H2,7,8)(H,9,10)/t3-/m0/s1
Canonical SMILES
NC(=O)CCC(N)C(=O)O
Isomeric SMILES
C(CC(=O)N)[C@@H](C(=O)O)N

Synonyms

  • glutamine
  • Levoglutamide
  • L-(+)-Glutamine
  • Cebrogen
  • Stimulina
  • glumin
  • Glutamic acid amide
  • Levoglutamid
  • Glavamin
  • (S)-2,5-Diamino-5-oxopentanoic acid
  • glutamic acid 5-amide
  • L-Glutamide
  • 2-aminoglutaramic acid
  • Nutrestore
  • Saforis
  • L-2-Aminoglutaramidic acid
  • L-Glutamin
  • L-Glutamic acid gamma-amide
  • Glumin (amino acid)
  • (2S)-2,5-diamino-5-oxopentanoic acid
  • L-2-Aminoglutaramic acid
  • Levoglutamida
  • Levoglutamidum
  • (2S)-2-amino-4-carbamoylbutanoic acid
  • Levoglutamina
Show all 39 synonyms
  • L-Glutaminsaeure-5-amid
  • gamma-Glutamine
  • Endari
  • glutamina
  • (2S)-2,5-diamino-5-oxopentanoate
  • Glutamine,l-
  • glutaminum
  • Glutacerebro
  • Glutaven
  • Memoril
  • GlutaSolve
  • l glutamine
  • D Glutamine
  • Q. Levoglutamide

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
White crystalline powderexp.
Melting point
184 to 185exp.
Density
1.364 g/cm³exp.
Solubility
In water, 41,300 mg/L at 25 °Cexp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
146.15 g/molcalc.
Exact mass
146.0691 Dacalc.
LogP (octanol/water)
-1.34calc.
Topological polar surface area
106.4 Ųcalc.
Hydrogen bond donors
3calc.
Hydrogen bond acceptors
3calc.
Rotatable bonds
4calc.
Heavy atoms
10calc.
Rings
0calc.
Aromatic rings
0calc.
Fraction sp3 carbons
0.6calc.
Formal charge
0calc.
Stereocentres
1calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Safety and hazards

GHS classification summary, not a safety data sheet

GHS classification
Hazard pictograms

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

L-Glutamine suppliers

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All 259 suppliers
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L-Glutamine price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Medicine, culture media, biochemical research, feed additive.

L-glutamine and its derivatives are used for treatment of stomach ulcers, L-Glutamine has been used as a remedy for gastric and duodenal ulcers.

Medical use: parenteral nutrition, treatment of mental disorders and alcoholism.

Use classes: Cosmetics.

Cosmetic ingredient, INCI name GLUTAMINE(antistatic, hair conditioning, skin conditioning)

Roles

  • Escherichia coli metabolite
  • Saccharomyces cerevisiae metabolite
  • animal metabolite
  • bacterial metabolite
  • enzyme inhibitor
  • eukaryotic metabolite
  • food component
  • fungal metabolite
  • human metabolite
  • mammalian metabolite
  • metabolite
  • micronutrient
  • mouse metabolite
  • nutraceutical
  • nutrient
  • pharmaceutical
  • physiological role
  • prokaryotic metabolite

Functional uses

  • Anti-static agent
  • Flavouring and nutrient
  • Softener and conditioner

Cosmetic functions

  • Antistatic
  • Hair conditioning
  • Skin conditioning

Pharmacology

Glutamine is an Amino Acid.

How it is made

Microbial L-glutamine producers were selected from wild type glutamate-producing coryneform bacteria. A sulfaguanidine resistant mutant of Brevibacterium flavum accumulates 41 g/L Lglutamine in 48 h from 10% glucose. A yield of 44% was achieved by the mutant Brevibacterium flavum AJ3409.

Synthesis: By isolation from sugar beet juice.

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • EU cosmetic ingredient inventory
  • Active ingredient in FDA approved drug labels

United States

  • TSCA inventory (USA)
    Status: Active in US commerce

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code L-Glutamine is traded under.

HS 2924.19Indicative HS code

Acyclic amides (including acyclic carbamates) and their derivatives, salts thereof, other

World exports in 2024
$2.38B
−1.7% vs 2023, imports $2.22B
2019 to 2024
Top exporters
  1. China34.7%
  2. Germany12.5%
  3. India * partner reported6.8%
Top importers
  1. United States17.5%
  2. Germany8.8%
  3. India * partner reported6.7%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for L-Glutamine is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about L-Glutamine, based on the data on this page

What is L-Glutamine?

L-glutamine is an optically active form of glutamine having L-configuration. It has a role as a micronutrient, a nutraceutical, an EC 1.14.13.39 (nitric oxide synthase) inhibitor, a mouse metabolite, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite and a human metabolite.

What is the CAS number of L-Glutamine?

The CAS registry number of L-Glutamine is 56-85-9. Other or deprecated CAS numbers: 6899-04-3.

What is the molecular formula and weight of L-Glutamine?

The molecular formula of L-Glutamine is C5H10N2O3 and its molar mass is 146.15 g/mol.

What is L-Glutamine used for?

Medicine, culture media, biochemical research, feed additive. L-glutamine and its derivatives are used for treatment of stomach ulcers, L-Glutamine has been used as a remedy for gastric and duodenal ulcers. Medical use: parenteral nutrition, treatment of mental disorders and alcoholism. Use classes: Cosmetics.

Is L-Glutamine hazardous?

No GHS hazard classification for L-Glutamine is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of L-Glutamine?

L-Glutamine is usually classified under HS code 292419 (Acyclic amides (including acyclic carbamates) and their derivatives, salts thereof, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy L-Glutamine?

CompoundList lists 259 suppliers of L-Glutamine in China, United States, India, Germany and 29 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy L-Glutamine in India?

36 suppliers in India list L-Glutamine on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of L-Glutamine?

Suppliers quote L-Glutamine on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle L-Glutamine

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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