L-Glutamine
Also known as glutamine, Levoglutamide, L-(+)-Glutamine
Key facts
What buyers check first
- Appearance
- White crystalline powder
- Melting point
- 184 to 185
- Density
- 1.364 g/cm³
- Solubility
- In water, 41,300 mg/L at 25 °C
- HS code
- 292419
- Category
- Amino acids and derivatives

What is L-Glutamine?
Plain description, key identifiers and synonyms
L-glutamine is an optically active form of glutamine having L-configuration. It has a role as a micronutrient, a nutraceutical, an EC 1.14.13.39 (nitric oxide synthase) inhibitor, a mouse metabolite, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite and a human metabolite. It is a L-alpha-amino acid, a glutamine family amino acid, a glutamine and a proteinogenic amino acid. It is a conjugate base of a L-glutaminium. It is a conjugate acid of a L-glutaminate. It is an enantiomer of a D-glutamine. It is a tautomer of a L-glutamine zwitterion.
Identifiers
Registry numbers, names and line notations, tap to copy
- IUPAC name
- (2S)-2,5-diamino-5-oxopentanoic acid
- CAS number
- 56-85-9 CAS number cross-checkedOther or deprecated CAS: 6899-04-3
- EC numbers
- 105-459-1, 200-292-1, 230-006-0
- Molecular formula
- C5H10N2O3
- UNII
- 0RH81L854J
- MDL number
- MFCD00008044
- INCI name
- GLUTAMINE
- InChIKey
- ZDXPYRJPNDTMRX-VKHMYHEASA-N
- InChI
- InChI=1S/C5H10N2O3/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H2,7,8)(H,9,10)/t3-/m0/s1
- Canonical SMILES
- NC(=O)CCC(N)C(=O)O
- Isomeric SMILES
- C(CC(=O)N)[C@@H](C(=O)O)N
Synonyms
- glutamine
- Levoglutamide
- L-(+)-Glutamine
- Cebrogen
- Stimulina
- glumin
- Glutamic acid amide
- Levoglutamid
- Glavamin
- (S)-2,5-Diamino-5-oxopentanoic acid
- glutamic acid 5-amide
- L-Glutamide
- 2-aminoglutaramic acid
- Nutrestore
- Saforis
- L-2-Aminoglutaramidic acid
- L-Glutamin
- L-Glutamic acid gamma-amide
- Glumin (amino acid)
- (2S)-2,5-diamino-5-oxopentanoic acid
- L-2-Aminoglutaramic acid
- Levoglutamida
- Levoglutamidum
- (2S)-2-amino-4-carbamoylbutanoic acid
- Levoglutamina
Show all 39 synonymsShow fewer synonyms
- L-Glutaminsaeure-5-amid
- gamma-Glutamine
- Endari
- glutamina
- (2S)-2,5-diamino-5-oxopentanoate
- Glutamine,l-
- glutaminum
- Glutacerebro
- Glutaven
- Memoril
- GlutaSolve
- l glutamine
- D Glutamine
- Q. Levoglutamide
Physical and chemical properties
Measured values and descriptors computed from the structure
Physical and chemical properties
Measured values, check the supplier specification for your grade
| Appearance | White crystalline powderexp.Measured value |
|---|---|
| Melting point | 184 to 185exp.Measured value |
| Density | 1.364 g/cm³exp.Measured value |
| Solubility | In water, 41,300 mg/L at 25 °Cexp.Measured value |
Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.
Computed descriptors
Calculated from the structure, useful for screening and formulation
| Molecular weight | 146.15 g/molcalc.Computed value |
|---|---|
| Exact mass | 146.0691 Dacalc.Computed value |
| LogP (octanol/water) | -1.34calc.Computed value |
| Topological polar surface area | 106.4 Ųcalc.Computed value |
| Hydrogen bond donors | 3calc.Computed value |
| Hydrogen bond acceptors | 3calc.Computed value |
| Rotatable bonds | 4calc.Computed value |
| Heavy atoms | 10calc.Computed value |
| Rings | 0calc.Computed value |
| Aromatic rings | 0calc.Computed value |
| Fraction sp3 carbons | 0.6calc.Computed value |
| Formal charge | 0calc.Computed value |
| Stereocentres | 1calc.Computed value |
| Lipinski rule of five | Passes (0 violations)calc.Computed value |
Calculated for screening. Confirm critical figures with the supplier.
Safety and hazards
GHS classification summary, not a safety data sheet
GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.
Full safety data and first aidL-Glutamine suppliers
Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings
- China, WuhanUnclaimed profileL-GlutamineGrade, purity and minimum order on requestPrice on request
- China, ShanghaiUnclaimed profileL-GlutamineGrade, purity and minimum order on requestPrice on request
- China, NingboUnclaimed profileL-GlutamineGrade, purity and minimum order on requestPrice on request
- Belgium, AartselaarUnclaimed profileL-GlutamineGrade, purity and minimum order on requestPrice on request
- Poland, WołówUnclaimed profileL-GlutamineGrade, purity and minimum order on requestPrice on request
- ChinaUnclaimed profileL-GlutamineGrade, purity and minimum order on requestPrice on request
- China, NingboUnclaimed profileL-GlutamineGrade, purity and minimum order on requestPrice on request
- Price on request
- China, BeijingUnclaimed profileL-GlutamineGrade, purity and minimum order on requestPrice on request
- Price on request
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Where suppliers are based
259 suppliers in 33 countries
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L-Glutamine price
Indicative price range per kg from live supplier offers
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Uses and applications
What the substance is used for, by industry and function
Medicine, culture media, biochemical research, feed additive.
L-glutamine and its derivatives are used for treatment of stomach ulcers, L-Glutamine has been used as a remedy for gastric and duodenal ulcers.
Medical use: parenteral nutrition, treatment of mental disorders and alcoholism.
Use classes: Cosmetics.
Industries and functions
Cosmetic ingredient, INCI name GLUTAMINE(antistatic, hair conditioning, skin conditioning)
Roles
- Escherichia coli metabolite
- Saccharomyces cerevisiae metabolite
- animal metabolite
- bacterial metabolite
- enzyme inhibitor
- eukaryotic metabolite
- food component
- fungal metabolite
- human metabolite
- mammalian metabolite
- metabolite
- micronutrient
- mouse metabolite
- nutraceutical
- nutrient
- pharmaceutical
- physiological role
- prokaryotic metabolite
Functional uses
- Anti-static agent
- Flavouring and nutrient
- Softener and conditioner
Cosmetic functions
- Antistatic
- Hair conditioning
- Skin conditioning
Pharmacology
Glutamine is an Amino Acid.
How it is made
Microbial L-glutamine producers were selected from wild type glutamate-producing coryneform bacteria. A sulfaguanidine resistant mutant of Brevibacterium flavum accumulates 41 g/L Lglutamine in 48 h from 10% glucose. A yield of 44% was achieved by the mutant Brevibacterium flavum AJ3409.
Synthesis: By isolation from sugar beet juice.
Regulatory status
Inventories, regulations and trade controls that list this substance
Health and food
- EU cosmetic ingredient inventory
- Active ingredient in FDA approved drug labels
United States
- TSCA inventory (USA)Status: Active in US commerce
HS code and trade data
Customs classification and reported world trade statistics
Global trade
World import and export statistics for the HS code L-Glutamine is traded under.
Acyclic amides (including acyclic carbamates) and their derivatives, salts thereof, other
- United States17.5%
- Germany8.8%
- India * partner reported6.7%
* Partner reported figures, a lower bound.
The HS code shown for L-Glutamine is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.
Frequently asked questions
Quick answers about L-Glutamine, based on the data on this page
What is L-Glutamine?
What is the CAS number of L-Glutamine?
What is the molecular formula and weight of L-Glutamine?
What is L-Glutamine used for?
Is L-Glutamine hazardous?
What is the HS code of L-Glutamine?
Where can I buy L-Glutamine?
Where can I buy L-Glutamine in India?
What is the price of L-Glutamine?
Guides for buyers
Practical guides that help when you source, ship or handle L-Glutamine
- Article, QualityPharma grades explained: IP vs BP vs USP vs EPWhat the Indian, British, US and European pharmacopoeias are, how their monographs differ, what multi grade claims mean and why a grade alone does not make a product fit for medicines.Read
- Article, SourcingHow to write an RFQ that gets fast and accurate quotesWhat suppliers need to quote quickly and comparably: exact product identity, quantity and packing, delivery terms, documents, samples and payment, with a ready to use template.Read
- Guide, Trade and logisticsHS codes for chemicals and why they matterHow the Harmonized System classifies chemicals, the chapters that matter, the rules for chemically defined compounds and mixtures, and practical steps to find the right code.Read
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