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Antibiotics and anti-infectives

Loracarbef

Also known as Lorabid, Loracarbefum, loracarbef anhydrous

CAS 76470-66-1Formula C16H16ClN3O4Molar mass 349.77 g/mol
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Loracarbef chemical structure, C16H16ClN3O4, CAS 76470-66-1
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
76470-66-1
Formula
C16H16ClN3O4
Molar mass
349.77 g/mol
HS code
294190
Category
Antibiotics and anti-infectives

What is Loracarbef?

Plain description, key identifiers and synonyms

Loracarbef is a synthetic "carba" analogue of cefaclor, with carbon replacing sulfur at position 1. Used to treat a wide range of infections caused by both gram-positive and gram-negative bacteria. It has a role as an antimicrobial agent and an antibacterial drug. It is a conjugate acid of a loracarbef anion. It is a tautomer of a loracarbef zwitterion.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(6R,7S)-7-[[(2R)-2-amino-2-phenylacetyl]amino]-3-chloro-8-oxo-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
CAS number
76470-66-1 CAS number cross-checked
Molecular formula
C16H16ClN3O4
UNII
W72I5ZT78Z
InChIKey
JAPHQRWPEGVNBT-UTUOFQBUSA-N
InChI
InChI=1S/C16H16ClN3O4/c17-9-6-7-10-12(15(22)20(10)13(9)16(23)24)19-14(21)11(18)8-4-2-1-3-5-8/h1-5,10-12H,6-7,18H2,(H,19,21)(H,23,24)/t10-,11-,12+/m1/s1
Canonical SMILES
NC(C(=O)NC1C(=O)N2C(C(=O)O)=C(Cl)CCC12)c1ccccc1
Isomeric SMILES
C1CC(=C(N2[C@H]1[C@@H](C2=O)NC(=O)[C@@H](C3=CC=CC=C3)N)C(=O)O)Cl

Synonyms

  • Lorabid
  • Loracarbefum
  • loracarbef anhydrous
  • Anhydrous loracarbef
  • Lorbef
  • Loracarbef, anhydrous
  • (6R,7S)-7-[(2R)-2-amino-2-phenylacetamido]-3-chloro-8-oxo-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
  • 1-Azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-(((2R)-aminophenylacetyl)amino)-3-chloro-8-oxo-, (6R,7S)-
  • 1-Azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-((aminophenylacetyl)amino)-3-chloro-8-oxo-, (6R-(6alpha,7beta(R*)))-
  • (6R,7S)-7-((2R)-2-amino-2-phenylacetamido)-3-chloro-8-oxo-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid
  • (6R, 7S)-7-((R)-2-Amino-2-phenylacetamido)-3-chloro-8-oxo-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic Acid, Monohydrate
  • 7-(((2R)-2-amino-2-phenyl-acetyl)amino)-3-chloro-8-oxo-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, hydrate
  • ly-163892 Monohydrate
  • Ly163892 monohydrate
  • (6R,7S)-7-[[(2R)-2-amino-2-phenylacetyl]amino]-3-chloro-8-oxo-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
  • Loracarbef (INN)
  • (6R,7S)-7-{[(2R)-2-amino-2-phenylacetyl]amino}-3-chloro-8-oxo-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
  • 1-Azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid, 7-[[(2R)-2-amino-2-phenylacetyl]amino]-3-chloro-8-oxo-, (6R,7S)-
  • KT 3777
  • KT 3777, LY 163892, Lorabid
  • Lorbef (TN)
  • Loracabef
  • LY 163892
  • 7beta-[(2R)-2-amino-2-phenylacetyl]nitrilo-3-chloro-3,4-didehydrocepham-4-carboxylic acid

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
349.77 g/molcalc.
Exact mass
349.0829 Dacalc.
LogP (octanol/water)
0.71calc.
Topological polar surface area
112.7 Ųcalc.
Hydrogen bond donors
3calc.
Hydrogen bond acceptors
4calc.
Rotatable bonds
4calc.
Heavy atoms
24calc.
Rings
3calc.
Aromatic rings
1calc.
Fraction sp3 carbons
0.31calc.
Formal charge
0calc.
Stereocentres
3calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C(Cc1ccccc1)NC1C(=O)N2C=CCCC12

O=C(Cc1ccccc1)NC1C(=O)N2C=CCCC12

3 rings, 19 atoms.

2 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Loracarbef suppliers

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Loracarbef price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Pharmacological actions

  • Anti-Bacterial Agents

Roles

  • antibacterial agent
  • antibacterial drug
  • antiinfective agent
  • antimicrobial agent
  • antimicrobial drug
  • pharmaceutical

Pharmacology

Loracarbef anhydrous is a Cephalosporin Antibacterial.

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Loracarbef is traded under.

HS 2941.90Indicative HS code

Antibiotics, other

World exports in 2024
$6.39B
+2.3% vs 2023, imports $6.97B
2019 to 2024
Top exporters
  1. China39.7%
  2. United States11.3%
  3. Switzerland * partner reported10.9%
Top importers
  1. Italy15.0%
  2. India * partner reported12.0%
  3. China8.7%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Loracarbef is indicative (it is known at chapter level only). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Loracarbef, based on the data on this page

What is Loracarbef?

Loracarbef is a synthetic "carba" analogue of cefaclor, with carbon replacing sulfur at position 1. Used to treat a wide range of infections caused by both gram-positive and gram-negative bacteria. It has a role as an antimicrobial agent and an antibacterial drug. It is a conjugate acid of a loracarbef anion.

What is the CAS number of Loracarbef?

The CAS registry number of Loracarbef is 76470-66-1.

What is the molecular formula and weight of Loracarbef?

The molecular formula of Loracarbef is C16H16ClN3O4 and its molar mass is 349.77 g/mol.

What is Loracarbef used for?

Known uses and roles of Loracarbef include antibacterials and antibiotics in pharmaceuticals, antibacterial agent, antibacterial drug, antiinfective agent, antimicrobial agent and 3 more.

Is Loracarbef hazardous?

No GHS hazard classification for Loracarbef is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Loracarbef?

Loracarbef is usually classified under HS code 294190 (Antibiotics, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Loracarbef?

Post a free request on CompoundList and suppliers of Loracarbef will send you quotes. Your contact details stay private until you accept a quote.

What is the price of Loracarbef?

Suppliers quote Loracarbef on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Loracarbef

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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