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Heterocyclic building blocks

Lorcaserin

Also known as (1R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine, lorcaserine, LorcaserinA

CAS 616202-92-7Formula C11H14ClNMolar mass 195.69 g/molEC 809-254-4
GHS signal word: Warning. Pictograms: Harmful or irritant, Hazardous to the environment 13 suppliers listed
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Lorcaserin chemical structure, C11H14ClN, CAS 616202-92-7
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
616202-92-7
Formula
C11H14ClN
Molar mass
195.69 g/mol
Solubility
White to off-white powder, solubility in water <400 mg/mL /Lorcaserin hydrochloride hemi…
HS code
293399
Category
Heterocyclic building blocks

What is Lorcaserin?

Plain description, key identifiers and synonyms

Lorcaserin is a benzazepine that is 2,3,4,5-tetrahydro-3-benzazepine substituted at position 1 by a methyl group and a t position 6 by a chloro group. It has a role as an appetite depressant and an anti-obesity agent. It is a benzazepine and an organochlorine compound.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(5R)-7-chloro-5-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine
CAS number
616202-92-7 CAS number cross-checked
EC number
809-254-4
Molecular formula
C11H14ClN
UNII
637E494O0Z
InChIKey
XTTZERNUQAFMOF-QMMMGPOBSA-N
InChI
InChI=1S/C11H14ClN/c1-8-7-13-5-4-9-2-3-10(12)6-11(8)9/h2-3,6,8,13H,4-5,7H2,1H3/t8-/m0/s1
Canonical SMILES
CC1CNCCc2ccc(Cl)cc21
Isomeric SMILES
C[C@H]1CNCCC2=C1C=C(C=C2)Cl

Synonyms

  • (1R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine
  • lorcaserine
  • LorcaserinA
  • lorcaserinum
  • (R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine
  • (R)-8-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine
  • (5R)-7-chloro-5-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine
  • 1H-3-Benzazepine, 8-chloro-2,3,4,5-tetrahydro-1-methyl-, (1R)-
  • (1R)-8-chloro-2,3,4,5-tetrahydro-1-methyl-1H-3-benzazepine
  • Belvig
  • Lorcaserin(free base)?

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Solubility
White to off-white powder, solubility in water <400 mg/mL /Lorcaserin hydrochloride hemihydrate//exp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
195.69 g/molcalc.
Exact mass
195.0815 Dacalc.
LogP (octanol/water)
2.59calc.
Topological polar surface area
12.03 Ųcalc.
Hydrogen bond donors
1calc.
Hydrogen bond acceptors
1calc.
Rotatable bonds
0calc.
Heavy atoms
13calc.
Rings
2calc.
Aromatic rings
1calc.
Fraction sp3 carbons
0.46calc.
Formal charge
0calc.
Stereocentres
1calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccc2c(c1)CCNCC2

c1ccc2c(c1)CCNCC2

2 rings, 11 atoms, the 2,3,4,5-Tetrahydro-1H-benzo(d)azepine ring system.

314 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant
GHS09: Hazardous to the environment
Hazardous to the environment

Hazard statements

  • H302Harmful if swallowed.
  • H400Very toxic to aquatic life.
  • H410Very toxic to aquatic life with long lasting effects.
Precautionary statements (7)
  • P264Wash skin thoroughly after handling.
  • P270Do not eat, drink or smoke when using this product.
  • P273Avoid release to the environment.
  • P301 + P317If swallowed: Get medical help.
  • P330Rinse mouth.
  • P391Collect spillage.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Lorcaserin suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 13 suppliers
13 of 13 offers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

13 suppliers in 3 countries

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Lorcaserin price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Roles

  • anti-obesity agent
  • appetite depressant
  • appetite regulator
  • cardiovascular drug
  • pharmaceutical
  • protective agent
  • renoprotective agent

Pharmacology

Lorcaserin is a Serotonin-2c Receptor Agonist. The mechanism of action of lorcaserin is as a Serotonin 2c Receptor Agonist and Cytochrome P450 2D6 Inhibitor.

Regulatory status

Inventories, regulations and trade controls that list this substance

Controls

  • US DEA controlled substance or listed chemical

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Lorcaserin is traded under.

HS 2933.99Indicative HS code

Heterocyclic compounds with nitrogen hetero-atom(s) only, other

World exports in 2024
$12.1B
−31.0% vs 2023, imports $28.8B
2019 to 2024
Top exporters
  1. China30.5%
  2. India * partner reported16.3%
  3. Ireland9.0%
Top importers
  1. Slovenia31.7%
  2. Italy24.2%
  3. United States5.0%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Lorcaserin is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Lorcaserin, based on the data on this page

What is Lorcaserin?

Lorcaserin is a benzazepine that is 2,3,4,5-tetrahydro-3-benzazepine substituted at position 1 by a methyl group and a t position 6 by a chloro group. It has a role as an appetite depressant and an anti-obesity agent. It is a benzazepine and an organochlorine compound.

What is the CAS number of Lorcaserin?

The CAS registry number of Lorcaserin is 616202-92-7.

What is the molecular formula and weight of Lorcaserin?

The molecular formula of Lorcaserin is C11H14ClN and its molar mass is 195.69 g/mol.

What is Lorcaserin used for?

Known uses and roles of Lorcaserin include building blocks in research and laboratory, screening compounds in research and laboratory, anti-obesity agent, appetite depressant, appetite regulator and 4 more.

Is Lorcaserin hazardous?

Lorcaserin carries the GHS signal word "Warning". Main hazards: harmful if swallowed, very toxic to aquatic life, very toxic to aquatic life with long lasting effects. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Lorcaserin?

Lorcaserin is usually classified under HS code 293399 (Heterocyclic compounds with nitrogen hetero-atom(s) only, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Lorcaserin?

CompoundList lists 13 suppliers of Lorcaserin in China, India and United States. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Lorcaserin in India?

2 suppliers in India list Lorcaserin on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Lorcaserin?

Suppliers quote Lorcaserin on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Lorcaserin

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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