CompoundList
Sign in
Cardiovascular and metabolic drugs

Lovastatin

Also known as mevinolin, Mevacor, Altoprev

CAS 75330-75-5Formula C24H36O5Molar mass 404.55 g/molEC 616-212-7
GHS signal word: Danger. Pictograms: Harmful or irritant, Serious health hazard 115 suppliers listed Drug substance
Get quotes Compare 115 suppliers
Lovastatin chemical structure, C24H36O5, CAS 75330-75-5
2D chemical structure

Key facts

What buyers check first

All properties
Appearance
White crystals
Melting point
179 °C
Solubility
In water, 0.4 × 10⁻³ mg/mL at 25 °C
HS code
293220
Category
Cardiovascular and metabolic drugs
Illustrative photo, colourless crystals in an open fibre drum in a chemical plant
Typical packagingIllustrative packaging image, not the actual product

What is Lovastatin?

Plain description, key identifiers and synonyms

Lovastatin is a fatty acid ester that is mevastatin carrying an additional methyl group on the carbobicyclic skeleton. It is used in as an anticholesteremic drug and has been found in fungal species such as Aspergillus terreus and Pleurotus ostreatus (oyster mushroom). It has a role as an antineoplastic agent, an anticholesteremic drug, a prodrug and an Aspergillus metabolite. It is a member of hexahydronaphthalenes, a delta-lactone, a polyketide, a fatty acid ester and a statin (naturally occurring). It is functionally related to a mevastatin and a (S)-2-methylbutyric acid.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
[(1S,3R,7S,8S,8aR)-8-[2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl] (2S)-2-methylbutanoate
CAS number
75330-75-5 CAS number cross-checked
EC numbers
616-212-7, 692-955-0, 946-962-3
Molecular formula
C24H36O5
UNII
9LHU78OQFD
MDL number
MFCD00072164
InChIKey
PCZOHLXUXFIOCF-BXMDZJJMSA-N
InChI
InChI=1S/C24H36O5/c1-5-15(3)24(27)29-21-11-14(2)10-17-7-6-16(4)20(23(17)21)9-8-19-12-18(25)13-22(26)28-19/h6-7,10,14-16,18-21,23,25H,5,8-9,11-13H2,1-4H3/t14-,15-,16-,18+,19+,20-,21-,23-/m0/s1
Canonical SMILES
CCC(C)C(=O)OC1CC(C)C=C2C=CC(C)C(CCC3CC(O)CC(=O)O3)C21
Isomeric SMILES
CC[C@H](C)C(=O)O[C@H]1C[C@H](C=C2[C@H]1[C@H]([C@H](C=C2)C)CC[C@@H]3C[C@H](CC(=O)O3)O)C

Synonyms

  • mevinolin
  • Mevacor
  • Altoprev
  • Mevlor
  • Sivlor
  • Altocor
  • Monacolin K
  • Lovastatine
  • 6alpha-Methylcompactin
  • Lovastatina
  • Mevinacor
  • Lovastatinum
  • 6-alpha-Methylcompactin
  • MK 803
  • (1S,3R,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl (2S)-2-methylbutanoate
  • [(1S,3R,7S,8S,8aR)-8-[2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl] (2S)-2-methylbutanoate
  • 2beta,6alpha-Dimethyl-8alpha-(2-methyl-1-oxobutoxy)-mevinic acid lactone
  • (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-Hexahydro-3,7-dimethyl-8-(2-(2R,4R)-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl)-1-naphthalenyl (S)-2-methyl-butyrate
  • 1,2,6,7,8,8a-Hexahydro-beta,delta-dihydroxy-2,6-dimethyl-8-(2-methyl-1-oxobutyoxy)-1-naphthaleneheptanoic acid delta-lactone
  • 6-Methylcompactin
  • Lovastatinum (Latin)
  • 1 alpha-Isomer Lovastatin
  • 6 Methylcompactin
  • (1S,3R,7S,8S,8aR)-8-(2-((2R,4R)-4-Hydroxy-6-oxooxan-2-yl)ethyl)-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl (2S)-2-methylbutanoate
  • alpha-Isomer Lovastatin, 1
Show all 36 synonyms
  • Mevinacor 10
  • Mevinacor 40
  • ((1S,3R,7S,8S,8aR)-8-(2-((2R,4R)-4-hydroxy-6-oxooxan-2-yl)ethyl)-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl) (2S)-2-methylbutanoate
  • Lovastatin, 1 alpha
  • (8-(2-(4-hydroxy-6-oxooxan-2-yl)ethyl)-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl) 2-methylbutanoate
  • ((1S,3R,7S,8S,8aR)-8-(2-((2R,4R)-4-hydroxy-6-oxooxan-2-yl)ethyl)-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl) (2R)-2-methylbutanoate
  • Lovalip
  • Lovalord
  • Nergadan
  • Artein
  • Hipolip

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
White crystalsexp.
Melting point
179 °Cexp.
Solubility
In water, 0.4 × 10⁻³ mg/mL at 25 °Cexp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
404.55 g/molcalc.
Exact mass
404.2563 Dacalc.
LogP (octanol/water)
4.2calc.
Topological polar surface area
72.83 Ųcalc.
Hydrogen bond donors
1calc.
Hydrogen bond acceptors
5calc.
Rotatable bonds
6calc.
Heavy atoms
29calc.
Rings
3calc.
Aromatic rings
0calc.
Fraction sp3 carbons
0.75calc.
Formal charge
0calc.
Stereocentres
8calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C1CCCC(CCC2CC=CC3=CCCCC32)O1

O=C1CCCC(CCC2CC=CC3=CCCCC32)O1

3 rings, 19 atoms.

80 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS07: Harmful or irritant
Harmful or irritant
GHS08: Serious health hazard
Serious health hazard

Hazard statements

  • H302Harmful if swallowed.
  • H317May cause an allergic skin reaction.
  • H351Suspected of causing cancer.
  • H361Suspected of damaging fertility or the unborn child.
  • H372Causes damage to organs through prolonged or repeated exposure.
Precautionary statements (17)
  • P203Obtain, read and follow all safety instructions before use.
  • P260Do not breathe dust, fume, gas, mist, vapours or spray.
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P270Do not eat, drink or smoke when using this product.
  • P272Contaminated work clothing should not be allowed out of the workplace.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P301 + P317If swallowed: Get medical help.
  • P302 + P352If on skin: Wash with plenty of water.
  • P318If exposed or concerned, get medical advice.
  • P319Get medical help if you feel unwell.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P330Rinse mouth.
  • P333 + P317If skin irritation or rash occurs: Get medical help.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Lovastatin suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 115 suppliers
30 of 30 offers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

115 suppliers in 18 countries

Send one request to many suppliers

Choose up to 10 suppliers or let us match your request. Compare quotes side by side, free.

Choose suppliersPost a request

Lovastatin price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

Get latest price

Uses and applications

What the substance is used for, by industry and function

Anticholesteremic Agents, Hydroxymethylglutaryl-CoA Reductase Inhibitors.

Lovastatin is ... used as starting material for the synthesis of simvastatin.

Pharmacological actions

  • Anticholesteremic Agents
  • Hydroxymethylglutaryl-CoA Reductase Inhibitors

Roles

  • Aspergillus metabolite
  • anti-HIV agent
  • anti-asthmatic agent
  • anti-inflammatory agent
  • antiatherosclerotic agent
  • anticholesteremic drug
  • antidyskinesia agent
  • antilipemic drug
  • antimicrobial agent
  • antineoplastic agent
  • antiparkinson drug
  • antirheumatic drug
  • antiviral agent
  • cardiovascular drug
  • eukaryotic metabolite
  • fungal metabolite
  • metabolite
  • pharmaceutical
  • pro-agent
  • prodrug

Pharmacology

Lovastatin is a HMG-CoA Reductase Inhibitor. The mechanism of action of lovastatin is as a Hydroxymethylglutaryl-CoA Reductase Inhibitor.

How it is made

Lovastatin is the delta-lactone of mevinolinic acid and is produced by fermentation of Aspergillus terreus. The drug has also been isolated as a fermentation metabolite of Monascus ruber.

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • Active ingredient in FDA approved drug labels

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Lovastatin is traded under.

HS 2932.20Indicative HS code

Lactones

World exports in 2024
$1.97B
−4.7% vs 2023, imports $2.07B
2019 to 2024
Top exporters
  1. China56.3%
  2. India * partner reported7.4%
  3. Germany7.3%
Top importers
  1. United States14.2%
  2. India * partner reported13.5%
  3. Brazil8.5%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Lovastatin is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Lovastatin, based on the data on this page

What is Lovastatin?

Lovastatin is a fatty acid ester that is mevastatin carrying an additional methyl group on the carbobicyclic skeleton. It is used in as an anticholesteremic drug and has been found in fungal species such as Aspergillus terreus and Pleurotus ostreatus (oyster mushroom).

What is the CAS number of Lovastatin?

The CAS registry number of Lovastatin is 75330-75-5.

What is the molecular formula and weight of Lovastatin?

The molecular formula of Lovastatin is C24H36O5 and its molar mass is 404.55 g/mol.

What is Lovastatin used for?

Anticholesteremic Agents, Hydroxymethylglutaryl-CoA Reductase Inhibitors. Lovastatin is ... used as starting material for the synthesis of simvastatin.

Is Lovastatin hazardous?

Lovastatin carries the GHS signal word "Danger". Main hazards: harmful if swallowed, may cause an allergic skin reaction, suspected of causing cancer. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Lovastatin?

Lovastatin is usually classified under HS code 293220 (Lactones). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Lovastatin?

CompoundList lists 115 suppliers of Lovastatin in United States, China, India, Germany and 14 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Lovastatin in India?

14 suppliers in India list Lovastatin on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Lovastatin?

Suppliers quote Lovastatin on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Lovastatin

Get quotes for Lovastatin

Post one free request with your grade, quantity and destination. Matching suppliers send quotes you can compare side by side.
Post a request Sell Lovastatin
Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
Embed this structure on your websiteShow code

Paste this code into your page to show the 2D structure of Lovastatin with a 3D view, its CAS number where known and a link back to this page. Free to use with the link kept.

<iframe src="https://www.compoundlist.com/embed/structure/lovastatin-75330-75-5" title="Lovastatin structure on CompoundList" width="360" height="420" style="border:1px solid #E7E2DA;border-radius:12px;max-width:100%" loading="lazy" referrerpolicy="strict-origin-when-cross-origin"></iframe>
Preview the embed

Explore more in Cardiovascular and metabolic drugs or HS code 293220

115 suppliers
Free quotes, contact stays private
Get quotes