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Mefenamic acid chemical structure, C15H15NO2, CAS 61-68-7
2D chemical structure

Key facts

What buyers check first

Appearance
Crystals
Melting point
230 to 231
Solubility
WHITE POWDER, SOLUBILITY IN WATER: GREATER THAN 5 G/100 ML /SODIUM SALT/
HS code
292249
Category
Analgesics and anti-inflammatories
Illustrative photo, a shrink wrapped pallet of kraft paper sacks in a chemical plant
Typical packagingIllustrative packaging image, not the actual product

What is Mefenamic acid?

Plain description, key identifiers and synonyms

Mefenamic acid is an aminobenzoic acid that is anthranilic acid in which one of the hydrogens attached to the nitrogen is replaced by a 2,3-dimethylphenyl group. Although classed as a non-steroidal anti-inflammatory drug, its anti-inflammatory properties are considered to be minor. It is used to relieve mild to moderate pain, including headaches, dental pain, osteoarthritis and rheumatoid arthritis. It has a role as a non-steroidal anti-inflammatory drug, an analgesic, an antipyretic, an EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor, a xenobiotic, an antirheumatic drug and an environmental contaminant. It is an aminobenzoic acid and a secondary amino compound.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
2-(2,3-dimethylanilino)benzoic acid
CAS number
61-68-7 CAS number cross-checked
EC number
200-513-1
Molecular formula
C15H15NO2
UNII
367589PJ2C
MDL number
MFCD00051721
InChIKey
HYYBABOKPJLUIN-UHFFFAOYSA-N
InChI
InChI=1S/C15H15NO2/c1-10-6-5-9-13(11(10)2)16-14-8-4-3-7-12(14)15(17)18/h3-9,16H,1-2H3,(H,17,18)
SMILES (canonical and isomeric)
CC1=C(C(=CC=C1)NC2=CC=CC=C2C(=O)O)C

Synonyms

  • Ponstel
  • 2-[(2,3-dimethylphenyl)amino]benzoic acid
  • Mephenamic acid
  • 2-((2,3-Dimethylphenyl)amino)benzoic acid
  • Mephenaminic acid
  • Ponstan
  • Methenamic acid
  • Vialidon
  • Lysalgo
  • Tanston
  • Acide mefenamique
  • Mefenaminsaeure
  • N-2,3-Xylylanthranilic acid
  • Acido mefenamico
  • Mefenaminic Acid
  • Acidum mefenamicum
  • INF 3355
  • N-(2,3-Xylyl)-2-aminobenzoic acid
  • N-(2,3-Dimethylphenyl)anthranilic acid
  • Gardan
  • Anthranilic acid, N-2,3-xylyl-
  • 2-(2,3-dimethylphenylamino)benzoic acid
  • Benzoic acid, 2-[(2,3-dimethylphenyl)amino]-
  • CN 35355
  • Benzoic acid, 2-(2,3-dimethylphenyl)amino-
Show all 38 synonyms
  • Benzoic acid, 2-((2,3-dimethylphenyl)amino)-
  • 2-Diphenylaminecarboxylic acid, 2',3'-dimethyl-
  • Mefenamicacid
  • Mendys
  • Ponstan fte
  • Opustan 250
  • Opustan 500
  • Dysman-250
  • Dysman-500
  • Meflam 250
  • Meflam 500
  • Acid, Mefenamic
  • Apo Mefenamic

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
Crystalsexp.
Melting point
230 to 231exp.
Solubility
WHITE POWDER, SOLUBILITY IN WATER: GREATER THAN 5 G/100 ML /SODIUM SALT/exp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
241.29 g/molcalc.
Exact mass
241.1103 Dacalc.
LogP (octanol/water)
3.75calc.
Topological polar surface area
49.33 ร…ยฒcalc.
Hydrogen bond donors
2calc.
Hydrogen bond acceptors
2calc.
Rotatable bonds
3calc.
Heavy atoms
18calc.
Rings
2calc.
Aromatic rings
2calc.
Fraction sp3 carbons
0.13calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccc(Nc2ccccc2)cc1

c1ccc(Nc2ccccc2)cc1

2 rings, 13 atoms, the Diphenylamine ring system.

3,181 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant
GHS08: Serious health hazard
Serious health hazard

Hazard statements

  • H302Harmful if swallowed.
  • H361Suspected of damaging fertility or the unborn child.
Precautionary statements (9)
  • P203Obtain, read and follow all safety instructions before use.
  • P264Wash skin thoroughly after handling.
  • P270Do not eat, drink or smoke when using this product.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P301 + P317If swallowed: Get medical help.
  • P318If exposed or concerned, get medical advice.
  • P330Rinse mouth.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Mefenamic acid suppliers

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Mefenamic acid price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Use classes: Pharmaceuticals.

Pharmacological actions

  • Anti-Inflammatory Agents, Non-Steroidal
  • Cyclooxygenase Inhibitors

Roles

  • analgesic
  • anti-inflammatory agent
  • anti-inflammatory drug
  • antipyretic
  • antirheumatic drug
  • environmental contaminant
  • enzyme inhibitor
  • hypoglycemic agent
  • non-steroidal anti-inflammatory drug
  • pharmaceutical
  • xenobiotic

Functional uses

  • Pharmaceutical

Pharmacology

Mefenamic acid is a Nonsteroidal Anti-inflammatory Drug. The mechanism of action of mefenamic acid is as a Cyclooxygenase Inhibitor.

How it is made

Prepd by copper-catalyzed condensation of o-chlorobenzoic acid & 2,3-dimethylaniline: winder...j pharmacol exp ther 138, 405 (1962), belg patent 605,302 (1961 to parke, davis).

O-chlorobenozic acid is condensed with 2,3-xylidene with aid of potassium carbonate & resulting potassium salt is treated with mineral acid to liberate desired acid. Us patent 3,138,636.

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • Active ingredient in FDA approved drug labels

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Mefenamic acid is traded under.

HS 2922.49Indicative HS code

Amino-acids, other than those containing more than one kind of oxygen function, andโ€ฆ

World exports in 2024
$3.88B
โˆ’11.5% vs 2023, imports $3.87B
2019 to 2024
Top exporters
  1. China38.7%
  2. India * partner reported8.3%
  3. Germany8.1%
Top importers
  1. United States13.4%
  2. Germany11.1%
  3. Japan6.6%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Mefenamic acid is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Mefenamic acid, based on the data on this page

What is Mefenamic acid?

Mefenamic acid is an aminobenzoic acid that is anthranilic acid in which one of the hydrogens attached to the nitrogen is replaced by a 2,3-dimethylphenyl group. Although classed as a non-steroidal anti-inflammatory drug, its anti-inflammatory properties are considered to be minor.

What is the CAS number of Mefenamic acid?

The CAS registry number of Mefenamic acid is 61-68-7.

What is the molecular formula and weight of Mefenamic acid?

The molecular formula of Mefenamic acid is C15H15NO2 and its molar mass is 241.29 g/mol.

What is Mefenamic acid used for?

Use classes: Pharmaceuticals.

Is Mefenamic acid hazardous?

Mefenamic acid carries the GHS signal word "Warning". Main hazards: harmful if swallowed, suspected of damaging fertility or the unborn child. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Mefenamic acid?

Mefenamic acid is usually classified under HS code 292249 (Amino-acids, other than those containing more than one kind of oxygen function, andโ€ฆ). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Mefenamic acid?

CompoundList lists 178 suppliers of Mefenamic acid in India, United States, China, Germany and 25 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Mefenamic acid in India?

43 suppliers in India list Mefenamic acid on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Mefenamic acid?

Suppliers quote Mefenamic acid on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Mefenamic acid

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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