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Menthone chemical structure, C10H18O, CAS 89-80-5
2D chemical structure

Key facts

What buyers check first

Appearance
Colorless, oily, mobile liq
Boiling point
210 °C
Solubility
Slightly sol in water, sol in org solvents /L-form/
HS code
291429
Category
Synthetic aroma chemicals
Illustrative photo, 200 litre steel drums of liquid in a chemical plant
Typical packagingIllustrative packaging image, not the actual product

What is Menthone?

Plain description, key identifiers and synonyms

(-)-menthone is a menthone that is cyclohexanone substituted by a methyl and an isopropyl group at positions 5 and 2 respectively (the 2S,5R-stereoisomer). It is an enantiomer of a (+)-menthone.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
trans-(2S,5R)-5-methyl-2-propan-2-ylcyclohexan-1-one
CAS number
89-80-5Other or deprecated CAS: 10458-14-7, 1074-95-9, 14073-97-3
EC numbers
201-941-1, 214-049-2, 237-926-1
Molecular formula
C10H18O
UNII
5F709W4OG4, 9NH5J4V8FN
MDL number
MFCD00001634, MFCD00136033
INCI name
L-MENTHANONE, MENTHONE
InChIKey
NFLGAXVYCFJBMK-BDAKNGLRSA-N
InChI
InChI=1S/C10H18O/c1-7(2)9-5-4-8(3)6-10(9)11/h7-9H,4-6H2,1-3H3/t8-,9+/m1/s1
Canonical SMILES
CC1CCC(C(C)C)C(=O)C1
Isomeric SMILES
C[C@@H]1CC[C@H](C(=O)C1)C(C)C

Synonyms

  • trans-Menthone
  • p-Menthone
  • trans-Menthan-3-one
  • Neomenthone
  • Menthone racemic
  • trans-p-Menthan-3-one
  • p-Menthan-3-one, trans-
  • Menthone G
  • (2S,5R)-5-methyl-2-propan-2-ylcyclohexan-1-one
  • Cyclohexanone, 5-methyl-2-(1-methylethyl)-, trans-
  • Cyclohexanone, 5-methyl-2-(1-methylethyl)-, (2R,5S)-rel-
  • Singleex isomenthone
  • Menthone, (a+-)-
  • (-)-Menthone
  • l-MENTHONE
  • (2S,5R)-2-isopropyl-5-methylcyclohexanone
  • DL-Menthone
  • L-Menthan-3-one
  • Cyclohexanone, 5-methyl-2-(1-methylethyl)-, (2S,5R)-
  • (1R,4S)-(-)-p-Menthan-3-one
  • (-)-(2S,5R)-Menthone
  • (1R,4S)-p-menthan-3-one
  • (2S,5R)-5-methyl-2-(propan-2-yl)cyclohexanone
  • (2S,5R)-2-Isopropyl-5-methylcyclohexan-1-one
  • (2S,5R)-5-methyl-2-(1-methylethyl)cyclohexanone
Show all 38 synonyms
  • (2S-trans)-5-methyl-2-(1-methylethyl)cyclohexanone
  • (-)-(1R,4S)-menthone
  • (2S,5R)-5-Methyl-2-(Propan-2-Yl)Cyclohexan-1-One
  • (2S,5R)-5-Methyl-2-(1-methylethyl)-cyclohexanone
  • (2S,5R)-2-isopropyl-5-methyl-cyclohexanone
  • (-)-5-Methyl-2-(1-methylethyl)cyclohexanone
  • (+/-)-menthone
  • rel-(2S,5R)-5-methyl-2-(1-methylethyl)-cyclohexanone
  • Cyclohexanone, 5-methyl-2-(1-methylethyl)-, (2S-trans)-
  • Menthone (natural)
  • p-Menthan-3-one racemic
  • (dl)-Menthone
  • (-)-Menthone (contains up to 15% D-Menthone)

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
Colorless, oily, mobile liqexp.
Odour
Slight peppermint odorexp.
Taste
Bitterexp.
Boiling point
210 °Cexp.
Solubility
Slightly sol in water, sol in org solvents /L-form/exp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
154.25 g/molcalc.
Exact mass
154.1358 Dacalc.
LogP (octanol/water)
2.65calc.
Topological polar surface area
17.07 Ųcalc.
Hydrogen bond donors
0calc.
Hydrogen bond acceptors
1calc.
Rotatable bonds
1calc.
Heavy atoms
11calc.
Rings
1calc.
Aromatic rings
0calc.
Fraction sp3 carbons
0.9calc.
Formal charge
0calc.
Stereocentres
2calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C1CCCCC1

O=C1CCCCC1

1 ring, 7 atoms, the Cyclohexanone ring system.

2,698 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS02: Flammable
Flammable
GHS07: Harmful or irritant
Harmful or irritant

Hazard statements

  • H226Flammable liquid and vapour.
  • H315Causes skin irritation.
  • H317May cause an allergic skin reaction.
  • H412Harmful to aquatic life with long lasting effects.
Precautionary statements (20)
  • P210Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
  • P233Keep container tightly closed.
  • P240Ground and bond container and receiving equipment.
  • P241Use explosion-proof electrical, ventilating and lighting equipment.
  • P242Use non-sparking tools.
  • P243Take action to prevent static discharges.
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P272Contaminated work clothing should not be allowed out of the workplace.
  • P273Avoid release to the environment.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P302 + P352If on skin: Wash with plenty of water.
  • P303 + P361 + P353If on skin (or hair): Take off immediately all contaminated clothing. Rinse skin with water or shower.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P332 + P317If skin irritation occurs: Get medical help.
  • P333 + P317If skin irritation or rash occurs: Get medical help.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P370 + P378In case of fire: Use appropriate media to extinguish.
  • P403 + P235Store in a well-ventilated place. Keep cool.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Menthone suppliers

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Where suppliers are based

47 suppliers in 9 countries

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Menthone price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

In perfume & flavor compositions (L-form).

Industrial uses: Fragrance.

Consumer uses: Fragrance.

Cosmetic ingredient, INCI name L-MENTHANONE(perfuming)

Functional uses

  • Flavouring and nutrient
  • Fragrance

Cosmetic functions

  • Perfuming

How it is made

By oxidation of menthol...

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • EU cosmetic ingredient inventory

United States

  • TSCA inventory (USA)
    Status: Active in US commerce

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Menthone is traded under.

HS 2914.29Indicative HS code

Cyclanic, cyclenic or cycloterpenic ketones without other oxygen function, other

World exports in 2024
$1B
+6.6% vs 2023, imports $980M
2019 to 2024
Top exporters
  1. China32.5%
  2. India * partner reported12.9%
  3. Germany12.3%
Top importers
  1. United States15.7%
  2. Japan8.7%
  3. Germany8.7%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Menthone is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Menthone, based on the data on this page

What is Menthone?

(-)-menthone is a menthone that is cyclohexanone substituted by a methyl and an isopropyl group at positions 5 and 2 respectively (the 2S,5R-stereoisomer). It is an enantiomer of a (+)-menthone.

What is the CAS number of Menthone?

The CAS registry number of Menthone is 89-80-5. Other or deprecated CAS numbers: 10458-14-7, 1074-95-9, 14073-97-3.

What is the molecular formula and weight of Menthone?

The molecular formula of Menthone is C10H18O and its molar mass is 154.25 g/mol.

What is Menthone used for?

In perfume & flavor compositions (L-form). Industrial uses: Fragrance. Consumer uses: Fragrance.

Is Menthone hazardous?

Menthone carries the GHS signal word "Warning". Main hazards: flammable liquid and vapour, causes skin irritation, may cause an allergic skin reaction. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Menthone?

Menthone is usually classified under HS code 291429 (Cyclanic, cyclenic or cycloterpenic ketones without other oxygen function, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Menthone?

CompoundList lists 47 suppliers of Menthone in United States, India, China, Switzerland and 5 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Menthone in India?

12 suppliers in India list Menthone on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Menthone?

Suppliers quote Menthone on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Menthone

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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