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Cardiovascular and metabolic drugs

Metformin

Also known as 1,1-Dimethylbiguanide, N,N-dimethylimidodicarbonimidic diamide, Metiguanide

CAS 657-24-9Formula C4H11N5Molar mass 129.17 g/molEC 211-517-8
GHS signal word: Warning. Pictograms: Harmful or irritant 107 suppliers listed Drug substance
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Metformin chemical structure, C4H11N5, CAS 657-24-9
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
657-24-9
Formula
C4H11N5
Molar mass
129.17 g/mol
EC number
211-517-8
HS code
292529
Category
Cardiovascular and metabolic drugs

What is Metformin?

Plain description, key identifiers and synonyms

Metformin is a member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1. It has a role as a geroprotector, a hypoglycemic agent, a xenobiotic and an environmental contaminant. It is functionally related to a biguanide. It is a conjugate base of a metformin(1+).

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
3-(diaminomethylidene)-1,1-dimethylguanidine
CAS number
657-24-9 CAS number cross-checkedOther or deprecated CAS: 1115-70-4
EC number
211-517-8
Molecular formula
C4H11N5
UNII
9100L32L2N
InChIKey
XZWYZXLIPXDOLR-UHFFFAOYSA-N
InChI
InChI=1S/C4H11N5/c1-9(2)4(7)8-3(5)6/h1-2H3,(H5,5,6,7,8)
SMILES (canonical and isomeric)
CN(C)C(=N)N=C(N)N

Synonyms

  • 1,1-Dimethylbiguanide
  • N,N-dimethylimidodicarbonimidic diamide
  • Metiguanide
  • Dimethylbiguanide
  • Metformine
  • N,N-Dimethylbiguanide
  • Metformina
  • N1,N1-Dimethylbiguanide
  • N,N-Dimethyldiguanide
  • 3-(diaminomethylidene)-1,1-dimethylguanidine
  • Diaformin
  • Dimethylbiguanid
  • Metformin extended release
  • Biguanide, 1,1-dimethyl-
  • Meguan
  • Novo-Metformin
  • Dimethylguanylguanidine
  • LA 6023
  • 2-carbamimidoyl-1,1-dimethylguanidine
  • 1-((diaminomethylidene)amino)-N,N-dimethylmethanimidamide
  • 1-carbamimidamido-N,N-dimethylmethanimidamide
  • Dimethylbiguanidine
  • Dimethyldiguanide
  • Imidodicarbonimidic diamide, N,N-dimethyl-
  • Imidodicarbonimidic diamide-, N,N-dimethyl-
Show all 38 synonyms
  • Metforminum
  • Fluamine
  • Haurymelin
  • Flumamine
  • Gliguanid
  • Melbin
  • 1,1-Dimethyl biguanide
  • Metformin (USAN/INN)
  • Dimethyldigua
  • Dianben
  • Obimet
  • N-dimethylbiguanide
  • 3-(diaminomethylene)-1,1-dimethyl-guanidine, hydrochloride

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
129.17 g/molcalc.
Exact mass
129.1014 Dacalc.
LogP (octanol/water)
-1.24calc.
Topological polar surface area
91.49 Ųcalc.
Hydrogen bond donors
3calc.
Hydrogen bond acceptors
1calc.
Rotatable bonds
0calc.
Heavy atoms
9calc.
Rings
0calc.
Aromatic rings
0calc.
Fraction sp3 carbons
0.5calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant

Hazard statements

  • H302Harmful if swallowed.
Precautionary statements (5)
  • P264Wash skin thoroughly after handling.
  • P270Do not eat, drink or smoke when using this product.
  • P301 + P317If swallowed: Get medical help.
  • P330Rinse mouth.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Metformin suppliers

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All 107 suppliers
30 of 30 offers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

107 suppliers in 27 countries

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Metformin price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

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Uses and applications

What the substance is used for, by industry and function

Veterinary medication:.

Hypoglycemic Agents.

Use classes: Alimentary tract and metabolism.

Industries and functions

Pharmacological actions

  • Hypoglycemic Agents

Roles

  • analgesic
  • anti-anaemic agent
  • anti-arrhythmia drug
  • anti-inflammatory agent
  • antiatherosclerotic agent
  • anticonvulsant
  • antidepressant
  • antiglaucoma drug
  • antihypertensive agent
  • antimalarial
  • antineoplastic agent
  • antiparkinson drug
  • antipsoriatic
  • antipsychotic agent
  • antirheumatic drug
  • antitubercular agent
  • anxiolytic drug
  • cardiovascular drug
  • environmental contaminant
  • geroprotector
  • hypoglycemic agent
  • immunosuppressive agent
  • insulin-sensitizing drug
  • leprostatic drug

Functional uses

  • Pharmaceutical

Pharmacology

Metformin is a Biguanide.

How it is made

By reaction of dimethylamine hydrochloride with dicyandiamide to yield the base. (Metformin hydrochloride)

Preparation: ... J.J. Sterne, United States of America patent 3174901 (1965 to Jan Marcel Didier Aron-Samuel). (Metformin)

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • EU Cosmetics Regulation Annex II, prohibited in cosmetics
    Name: Metformin (INN) and its salts, Ref no: 147, Annex ref: II/147
  • Active ingredient in FDA approved drug labels

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Metformin is traded under.

HS 2925.29Indicative HS code

Imines and their derivatives, salts thereof, other

World exports in 2024
$1.8B
+12.4% vs 2023, imports $1.84B
2019 to 2024
Top exporters
  1. China35.9%
  2. France * partner reported15.5%
  3. Germany9.1%
Top importers
  1. United States13.3%
  2. China13.0%
  3. Brazil9.7%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Metformin is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Metformin, based on the data on this page

What is Metformin?

Metformin is a member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1. It has a role as a geroprotector, a hypoglycemic agent, a xenobiotic and an environmental contaminant. It is functionally related to a biguanide. It is a conjugate base of a metformin(1+).

What is the CAS number of Metformin?

The CAS registry number of Metformin is 657-24-9. Other or deprecated CAS numbers: 1115-70-4.

What is the molecular formula and weight of Metformin?

The molecular formula of Metformin is C4H11N5 and its molar mass is 129.17 g/mol.

What is Metformin used for?

Veterinary medication:. Hypoglycemic Agents. Use classes: Alimentary tract and metabolism.

Is Metformin hazardous?

Metformin carries the GHS signal word "Warning". Main hazards: harmful if swallowed. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Metformin?

Metformin is usually classified under HS code 292529 (Imines and their derivatives, salts thereof, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Metformin?

CompoundList lists 107 suppliers of Metformin in India, United States, China, Bangladesh and 23 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Metformin in India?

30 suppliers in India list Metformin on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Metformin?

Suppliers quote Metformin on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Metformin

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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