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Cosmetic ingredients

Methanediol

Also known as Methylene glycol, dihydroxymethane, formaldehyde hydrate

CAS 463-57-0Formula CH4O2Molar mass 48.04 g/molEC 207-339-5
3 suppliers listed
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Methanediol chemical structure, CH4O2, CAS 463-57-0
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
463-57-0
Formula
CH4O2
Molar mass
48.04 g/mol
EC number
207-339-5
HS code
290539
Category
Cosmetic ingredients

What is Methanediol?

Plain description, key identifiers and synonyms

Methanediol is the simplest member of the class of methanediols that is methane in which two of the hydrogens have been substituted by hydroxy groups. It is a member of methanediols, an aldehyde hydrate and a one-carbon compound.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
methanediol
CAS number
463-57-0 CAS number cross-checked
EC number
207-339-5
Molecular formula
CH4O2
UNII
6Z20YM9257
INCI name
METHYLENE GLYCOL
InChIKey
CKFGINPQOCXMAZ-UHFFFAOYSA-N
InChI
InChI=1S/CH4O2/c2-1-3/h2-3H,1H2
SMILES (canonical and isomeric)
C(O)O

Synonyms

  • Methylene glycol
  • dihydroxymethane
  • formaldehyde hydrate
  • Methandiol
  • Methanediol-
  • Paraformaldehyde, powder
  • Aldacide, Flo-Mor, Granuform, Paraform, TransFix

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
48.04 g/molcalc.
Exact mass
48.0211 Dacalc.
LogP (octanol/water)
-1.07calc.
Topological polar surface area
40.46 Ųcalc.
Hydrogen bond donors
2calc.
Hydrogen bond acceptors
2calc.
Rotatable bonds
0calc.
Heavy atoms
3calc.
Rings
0calc.
Aromatic rings
0calc.
Fraction sp3 carbons
1calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Methanediol suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 3 suppliers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

3 suppliers in 2 countries

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Methanediol price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

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Uses and applications

What the substance is used for, by industry and function

Cosmetic ingredient, INCI name METHYLENE GLYCOL(nail conditioning, nail sculpting)

Functional uses

  • Biocide
  • Softener and conditioner

Cosmetic functions

  • Nail conditioning
  • Nail sculpting

Pharmacology

Formaldehyde Solution is a saturated solution of formaldehyde, water, and typically another agent, most commonly methanol. In its typical form, formalin is 37% formaldehyde by weight (40% by volume), 6-13% methanol, and the rest water.

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • EU cosmetic ingredient inventory
  • EU Cosmetics Regulation Annex II, prohibited in cosmetics
    Name: Methanediol, methylene glycol, Ref no: 1579, Annex ref: II/1579

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Methanediol is traded under.

HS 2905.39Indicative HS code

Diols, other

World exports in 2024
$1.92B
−3.5% vs 2023, imports $2B
2019 to 2024
Top exporters
  1. China22.3%
  2. United States17.9%
  3. Germany16.1%
Top importers
  1. Germany12.0%
  2. China11.3%
  3. South Korea10.5%
Reported customs values in USD, not prices.Full trade data

The HS code shown for Methanediol is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Methanediol, based on the data on this page

What is Methanediol?

Methanediol is the simplest member of the class of methanediols that is methane in which two of the hydrogens have been substituted by hydroxy groups. It is a member of methanediols, an aldehyde hydrate and a one-carbon compound.

What is the CAS number of Methanediol?

The CAS registry number of Methanediol is 463-57-0.

What is the molecular formula and weight of Methanediol?

The molecular formula of Methanediol is CH4O2 and its molar mass is 48.04 g/mol.

What is Methanediol used for?

Known uses and roles of Methanediol include nail conditioning, nail sculpting, biocide and softener and conditioner.

Is Methanediol hazardous?

No GHS hazard classification for Methanediol is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Methanediol?

Methanediol is usually classified under HS code 290539 (Diols, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Methanediol?

CompoundList lists 3 suppliers of Methanediol in China and United States. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Methanediol?

Suppliers quote Methanediol on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Methanediol

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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