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Heterocyclic building blocks

Methazolamide

Also known as Methenamide, Neptazane, Neptazaneat

CAS 554-57-4Formula C5H8N4O3S2Molar mass 236.28 g/molEC 209-066-7
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Methazolamide chemical structure, C5H8N4O3S2, CAS 554-57-4
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
554-57-4
Formula
C5H8N4O3S2
Molar mass
236.28 g/mol
EC number
209-066-7
HS code
293590
Category
Heterocyclic building blocks

What is Methazolamide?

Plain description, key identifiers and synonyms

Methazolamide is a sulfonamide and a member of thiadiazoles.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
N-(3-methyl-5-sulfamoyl-1,3,4-thiadiazol-2-ylidene)acetamide
CAS number
554-57-4 CAS number cross-checkedOther or deprecated CAS: 1164547-86-7, 2101958-72-7
EC number
209-066-7
Molecular formula
C5H8N4O3S2
UNII
DA43GW06P1, W733B0S9SD
MDL number
MFCD00083416
InChIKey
FLOSMHQXBMRNHR-UHFFFAOYSA-N
InChI
InChI=1S/C5H8N4O3S2/c1-3(10)7-4-9(2)8-5(13-4)14(6,11)12/h1-2H3,(H2,6,11,12)
SMILES (canonical and isomeric)
CC(=O)N=C1N(N=C(S1)S(=O)(=O)N)C

Synonyms

  • Methenamide
  • Neptazane
  • Neptazaneat
  • Naptazane
  • Metazolamida
  • N-(3-methyl-5-sulfamoyl-1,3,4-thiadiazol-2-ylidene)acetamide
  • Methazolamide, (Z)-
  • N-(3-Methyl-5-Sulfamoyl-1,3,4-Thiadiazol-2(3h)-Ylidene)acetamide
  • Acetamide, N-[5-(aminosulfonyl)-3-methyl-1,3,4-thiadiazol-2(3H)-ylidene]-
  • N-[(2E)-3-Methyl-5-sulfamoyl-2,3-dihydro-1,3,4-thiadiazol-2-ylidene]acetamide
  • 4-27-00-08221 (Beilstein Handbook Reference)
  • Acetamide, N-(5-(aminosulfonyl)-3-methyl-1,3,4-thiadiazol-2(3H)-ylidene)-
  • N-(3-methyl-5-sulfamoyl-2,3-dihydro-1,3,4-thiadiazol-2-ylidene)acetamide
  • Metazolamide
  • (NE)-N-(3-methyl-5-sulfamoyl-1,3,4-thiadiazol-2-ylidene)acetamide
  • Methazolamidum
  • Acetamide, N-(4-methyl-2-sulfamoyl-delta2-1,3,4-thiadiazolin-5-ylidene)-
  • Acetamide, N-(5-(aminosulfonyl)-3-methyl-1,3,4-thiadiazol-2(3H)-ylidene)-, (N(Z))-
  • Methe
  • 2-Acetylimino-3-methyl-delta(4)-1,3,4-thiadiazoline-5-sulfonamide
  • 3-methyl-2-(2-oxo-1-azapropylidene)-1,3,4-thiadiazoline-5-sulfonamide
  • 5-Acetylimino-4-methyl-delta(2)-1,3,4-thiadiazoline-2-sulfonamide
  • N-(4-Methyl-2-sulfamoyl-delta2-1,3,4-thiadiazolin-5-ylidene)acetamide
  • N-(5-(Aminosulfonyl)-3-methyl-1,3,4-thiadiazol-2(3H)-ylidene)acetamide #
  • N-[5-(aminosulfonyl)-3-methyl-1,3,4-thiadiazol-2(3H)-ylidene]acetamide,
Show all 32 synonyms
  • (Z)-methazolamide
  • Neptazane (TN)
  • Methazolamide, MZA
  • Methazolamide (MZA)
  • Methazolamide (Standard)
  • 2-Acetylimino-3-methyl-delta(sup 4)-1,3,4-thiadiazoline-5-sulfonamide
  • 5-Acetylimino-4-methyl-delta(sup 2)-1,3,4-thiadiazoline-2-sulfonamide

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
236.28 g/molcalc.
Exact mass
236.0038 Dacalc.
LogP (octanol/water)
-1.42calc.
Topological polar surface area
107.4 Ųcalc.
Hydrogen bond donors
1calc.
Hydrogen bond acceptors
5calc.
Rotatable bonds
1calc.
Heavy atoms
14calc.
Rings
1calc.
Aromatic rings
1calc.
Fraction sp3 carbons
0.4calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, N=c1[nH]ncs1

N=c1[nH]ncs1

1 ring, 6 atoms, the 1,3,4-Thiadiazol-2-amine ring system.

17 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Methazolamide suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 25 suppliers
25 of 25 offers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

25 suppliers in 8 countries

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Methazolamide price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

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Uses and applications

What the substance is used for, by industry and function

Use classes: Pharmaceuticals.

Roles

  • antiglaucoma drug
  • antineoplastic agent
  • ophthalmology drug
  • pharmaceutical

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Methazolamide is traded under.

HS 2935.90Indicative HS code

Sulphonamides, other

World exports in 2024
$5.64B
−11.0% vs 2023, imports $8.56B
2019 to 2024
Top exporters
  1. Ireland43.1%
  2. China12.0%
  3. India * partner reported9.5%
Top importers
  1. United States23.6%
  2. Slovenia19.1%
  3. Spain11.7%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Methazolamide is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Methazolamide, based on the data on this page

What is Methazolamide?

Methazolamide is a sulfonamide and a member of thiadiazoles.

What is the CAS number of Methazolamide?

The CAS registry number of Methazolamide is 554-57-4. Other or deprecated CAS numbers: 1164547-86-7, 2101958-72-7.

What is the molecular formula and weight of Methazolamide?

The molecular formula of Methazolamide is C5H8N4O3S2 and its molar mass is 236.28 g/mol.

What is Methazolamide used for?

Use classes: Pharmaceuticals.

Is Methazolamide hazardous?

No GHS hazard classification for Methazolamide is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Methazolamide?

Methazolamide is usually classified under HS code 293590 (Sulphonamides, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Methazolamide?

CompoundList lists 25 suppliers of Methazolamide in China, United States, Canada, India and 4 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Methazolamide in India?

3 suppliers in India list Methazolamide on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Methazolamide?

Suppliers quote Methazolamide on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Methazolamide

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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