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Impurities and reference standards

Minnelide

Also known as 14-O-Phosphonooxymethyltriptolide disodium salt, Triptolide Impurity 1

CAS 1254702-87-8Formula C21H25Na2O10PMolar mass 514.38 g/mol
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Minnelide chemical structure, C21H25Na2O10P, CAS 1254702-87-8
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
1254702-87-8
Formula
C21H25Na2O10P
Molar mass
514.38 g/mol
HS code
293220
Category
Impurities and reference standards

What is Minnelide?

Plain description, key identifiers and synonyms

Triptolide Analog is a water soluble analog of the diterpenoid triepoxide triptolide isolated from the Chinese herb Tripterygium wilfordii Hook.f., with potential antineoplastic activity. Upon intravenous administration, the triptolide analog inhibits heat shock protein 70 (HSP70) and prevents HSP70-mediated inhibition of apoptosis. This leads to both the induction of apoptosis and a reduction of cancer cell growth. HSP70, a molecular chaperone upregulated in various cancer cells, plays a key role in the inhibition of caspase-dependent and -independent apoptosis.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
disodium, [(1S,2S,4S,5S,7S,8R,9R,11S,13S)-1-methyl-17-oxo-7-propan-2-yl-3,6,10,16-tetraoxaheptacyclo[11.7.0.02,4.02,9.05,7.09,11.014,18]icos-14(18)-en-8-yl]oxymethyl phosphate
CAS number
1254702-87-8
Molecular formula
C21H25Na2O10P
UNII
1CIV2UMO40
InChIKey
ZHBJMVNZRZUQEP-KIKMAQITSA-L
InChI
InChI=1S/C21H27O10P.2Na/c1-9(2)19-14(30-19)15-21(31-15)18(3)5-4-10-11(7-26-16(10)22)12(18)6-13-20(21,29-13)17(19)27-8-28-32(23,24)25;;/h9,12-15,17H,4-8H2,1-3H3,(H2,23,24,25);;/q;2*+1/p-2/t12-,13-,14-,15-,17+,18-,19-,20+,21+;;/m0../s1
Canonical SMILES
CC(C)C12OC1C1OC13C1(C)CCC4=C(COC4=O)C1CC1OC13C2OCOP(=O)([O-])[O-].[Na+].[Na+]
Isomeric SMILES
CC(C)[C@@]12[C@@H](O1)[C@H]3[C@@]4(O3)[C@]5(CCC6=C([C@@H]5C[C@H]7[C@]4([C@@H]2OCOP(=O)([O-])[O-])O7)COC6=O)C.[Na+].[Na+]

Synonyms

  • 14-O-Phosphonooxymethyltriptolide disodium salt
  • Triptolide Impurity 1

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
514.38 g/molcalc.
Exact mass
514.0981 Dacalc.
LogP (octanol/water)
-6.06calc.
Topological polar surface area
145.5 Ųcalc.
Hydrogen bond donors
0calc.
Hydrogen bond acceptors
10calc.
Rotatable bonds
5calc.
Heavy atoms
34calc.
Rings
7calc.
Aromatic rings
0calc.
Fraction sp3 carbons
0.86calc.
Formal charge
0calc.
Stereocentres
9calc.
Components
3calc.
Lipinski rule of five
Passes (1 violation)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C1OCC2=C1CCC1C2CC2OC23CC2OC2C2OC123

O=C1OCC2=C1CCC1C2CC2OC23CC2OC2C2OC123

7 rings, 21 atoms.

13 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Minnelide suppliers

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Minnelide price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Pharmacological actions

  • Antineoplastic Agents, Alkylating

Roles

  • antineoplastic agent
  • pharmaceutical

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Minnelide is traded under.

HS 2932.20Indicative HS code

Lactones

World exports in 2024
$1.97B
−4.7% vs 2023, imports $2.07B
2019 to 2024
Top exporters
  1. China56.3%
  2. India * partner reported7.4%
  3. Germany7.3%
Top importers
  1. United States14.2%
  2. India * partner reported13.5%
  3. Brazil8.5%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Minnelide is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Minnelide, based on the data on this page

What is Minnelide?

Triptolide Analog is a water soluble analog of the diterpenoid triepoxide triptolide isolated from the Chinese herb Tripterygium wilfordii Hook.f., with potential antineoplastic activity.

What is the CAS number of Minnelide?

The CAS registry number of Minnelide is 1254702-87-8.

What is the molecular formula and weight of Minnelide?

The molecular formula of Minnelide is C21H25Na2O10P and its molar mass is 514.38 g/mol.

What is Minnelide used for?

Known uses and roles of Minnelide include antineoplastic agent, pharmaceutical and antineoplastic agents, alkylating.

Is Minnelide hazardous?

No GHS hazard classification for Minnelide is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Minnelide?

Minnelide is usually classified under HS code 293220 (Lactones). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Minnelide?

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What is the price of Minnelide?

Suppliers quote Minnelide on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Minnelide

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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