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Hormones and steroids

Mometasone

Also known as (+)-Mometasone, Mometasona, Mometasonum

CAS 105102-22-5Formula C22H28Cl2O4Molar mass 427.37 g/molEC 818-819-4
GHS signal word: Danger. Pictograms: Serious health hazard 45 suppliers listed Drug substance
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Mometasone chemical structure, C22H28Cl2O4, CAS 105102-22-5
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
105102-22-5
Formula
C22H28Cl2O4
Molar mass
427.37 g/mol
EC number
818-819-4
HS code
293722
Category
Hormones and steroids

What is Mometasone?

Plain description, key identifiers and synonyms

Mometasone is a tertiary alpha-hydroxy ketone, a 17alpha-hydroxy steroid, an 11beta-hydroxy steroid, a 20-oxo steroid, a 3-oxo-Delta(1),Delta(4)-steroid and a chlorinated steroid. It has a role as an anti-inflammatory drug, a dermatologic drug, a vasoconstrictor agent and an anti-allergic agent. It is functionally related to a Delta(1)-progesterone.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(8S,9R,10S,11S,13S,14S,16R,17R)-9-chloro-17-(2-chloroacetyl)-11,17-dihydroxy-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
CAS number
105102-22-5 CAS number cross-checked
EC number
818-819-4
Molecular formula
C22H28Cl2O4
UNII
8HR4QJ6DW8
InChIKey
QLIIKPVHVRXHRI-CXSFZGCWSA-N
InChI
InChI=1S/C22H28Cl2O4/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,24)17(26)10-20(16,3)22(12,28)18(27)11-23/h6-7,9,12,15-17,26,28H,4-5,8,10-11H2,1-3H3/t12-,15+,16+,17+,19+,20+,21+,22+/m1/s1
Canonical SMILES
CC1CC2C3CCC4=CC(=O)C=CC4(C)C3(Cl)C(O)CC2(C)C1(O)C(=O)CCl
Isomeric SMILES
C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@@]4([C@]3([C@H](C[C@@]2([C@]1(C(=O)CCl)O)C)O)Cl)C

Synonyms

  • (+)-Mometasone
  • Mometasona
  • Mometasonum
  • (8S,9R,10S,11S,13S,14S,16R,17R)-9-chloro-17-(2-chloroacetyl)-11,17-dihydroxy-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
  • 9,21-dichloro-11beta,17-dihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione
  • Pregna-1,4-diene-3,20-dione, 9,21-dichloro-11,17-dihydroxy-16-methyl-, (11beta,16alpha)-
  • (1R,2S,10S,11S,13R,14R,15S,17S)-1-chloro-14-(2-chloroacetyl)-14,17-dihydroxy-2,13,15-trimethyltetracyclo(8.7.0.0^(2,7).0^(11,15))heptadeca-3,6-dien-5-one
  • (1R,2S,10S,11S,13R,14R,15S,17S)-1-chloro-14-(2-chloroacetyl)-14,17-dihydroxy-2,13,15-trimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-dien-5-one
  • (8S,9R,10S,11S,13S,14S,16R,17R)-9-chloro-17-(2-chloroacetyl)-11,17-dihydroxy-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta(a)phenanthren-3-one
  • Mometasone furoate EP impurity G
  • Mometasone (INN)
  • (11beta,16alpha)-9,21-Dichloro-11,17-dihydroxy-16-methylpregna-1,4-diene-3,20-dione
  • C22H28Cl2O4
  • mometazone
  • Mometasone, nasal
  • 9,21-Dichloro-11beta,17-dihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione (Mometasone)
  • Elocon (topical)
  • Mometasone, inhaled
  • Mometasone, topical
  • Mometasone (Standard)
  • Mometasone Furoate Impurity G
  • Mometasone Solution in Methanol, 100ug/mL
  • Mometasone Solution in Methanol, 1000ug/mL
  • Pregna-1,4-diene-3,20-dione, 9,21-dichloro-11,17-dihydroxy-16-methyl-, (11beta,16.alpha.)-

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
427.37 g/molcalc.
Exact mass
426.1365 Dacalc.
LogP (octanol/water)
3.41calc.
Topological polar surface area
74.6 Ųcalc.
Hydrogen bond donors
2calc.
Hydrogen bond acceptors
4calc.
Rotatable bonds
2calc.
Heavy atoms
28calc.
Rings
4calc.
Aromatic rings
0calc.
Fraction sp3 carbons
0.73calc.
Formal charge
0calc.
Stereocentres
8calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C1C=CC2C(=C1)CCC1C3CCCC3CCC21

O=C1C=CC2C(=C1)CCC1C3CCCC3CCC21

4 rings, 18 atoms.

956 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS08: Serious health hazard
Serious health hazard

Hazard statements

  • H360May damage fertility or the unborn child.
  • H361Suspected of damaging fertility or the unborn child.
  • H413May cause long lasting harmful effects to aquatic life.
Precautionary statements (6)
  • P203Obtain, read and follow all safety instructions before use.
  • P273Avoid release to the environment.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P318If exposed or concerned, get medical advice.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Mometasone suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 45 suppliers
30 of 30 offers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

45 suppliers in 17 countries

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Mometasone price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

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Uses and applications

What the substance is used for, by industry and function

Roles

  • anti-allergic agent
  • anti-anaemic agent
  • anti-inflammatory agent
  • anti-inflammatory drug
  • cardiovascular drug
  • dermatologic drug
  • pharmaceutical
  • vasoconstrictor agent

Pharmacology

Mometasone is a Corticosteroid. The mechanism of action of mometasone is as a Corticosteroid Hormone Receptor Agonist and Corticosteroid Hormone Receptor Agonist.

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • Active ingredient in FDA approved drug labels

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Mometasone is traded under.

HS 2937.22Indicative HS code

Halogenated derivatives of corticosteroidal hormones

World exports in 2024
$1.65B
−29.3% vs 2023, imports $1.67B
2019 to 2024
Top exporters
  1. United Kingdom69.1%
  2. Italy7.8%
  3. Singapore5.6%
Top importers
  1. United States64.5%
  2. Spain5.1%
  3. United Kingdom3.7%
Reported customs values in USD, not prices.Full trade data

The HS code shown for Mometasone is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Mometasone, based on the data on this page

What is Mometasone?

Mometasone is a tertiary alpha-hydroxy ketone, a 17alpha-hydroxy steroid, an 11beta-hydroxy steroid, a 20-oxo steroid, a 3-oxo-Delta(1),Delta(4)-steroid and a chlorinated steroid. It has a role as an anti-inflammatory drug, a dermatologic drug, a vasoconstrictor agent and an anti-allergic agent.

What is the CAS number of Mometasone?

The CAS registry number of Mometasone is 105102-22-5.

What is the molecular formula and weight of Mometasone?

The molecular formula of Mometasone is C22H28Cl2O4 and its molar mass is 427.37 g/mol.

What is Mometasone used for?

Known uses and roles of Mometasone include anti-inflammatories in pharmaceuticals, hormones and steroids in pharmaceuticals, anti-allergic agent, anti-anaemic agent, anti-inflammatory agent and 5 more.

Is Mometasone hazardous?

Mometasone carries the GHS signal word "Danger". Main hazards: may damage fertility or the unborn child, suspected of damaging fertility or the unborn child, may cause long lasting harmful effects to aquatic life. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Mometasone?

Mometasone is usually classified under HS code 293722 (Halogenated derivatives of corticosteroidal hormones). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Mometasone?

CompoundList lists 45 suppliers of Mometasone in United States, China, Spain, Hong Kong and 13 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Mometasone in India?

2 suppliers in India list Mometasone on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Mometasone?

Suppliers quote Mometasone on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Mometasone

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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