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Murcko scaffold

Ring system with 4 rings and 18 atoms

957 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
18
Chemicals
957
With full pages
183
Scaffold SMILES

O=C1C=CC2C(=C1)CCC1C3CCCC3CCC21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1C=CC2C(=C1)CCC1C3CCCC3CCC21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 957 chemicals

11,17,21-Trihydroxypregna-1,4-diene-3,20-dione chemical structure, C21H28O5, CAS 307518-72-5
11,17,21-Trihydroxypregna-1,4-diene-3,20-dione
CAS 307518-72-5C21H28O5
Dexamethasone chemical structure, C22H29FO5, CAS 50-02-2
Dexamethasone
CAS 50-02-2C22H29FO5
Prednisolone chemical structure, C21H28O5, CAS 50-24-8
Prednisolone
CAS 50-24-8C21H28O5
Prednisolone acetate chemical structure, C23H30O6, CAS 52-21-1
Prednisolone acetate
CAS 52-21-1C23H30O6
Paramethasone chemical structure, C22H29FO5, CAS 53-33-8
Paramethasone
CAS 53-33-8C22H29FO5
Fluprednisolone chemical structure, C21H27FO5, CAS 53-34-9
Fluprednisolone
CAS 53-34-9C21H27FO5
Methylprednisolone acetate chemical structure, C24H32O6, CAS 53-36-1
Methylprednisolone acetate
CAS 53-36-1C24H32O6
Triamcinolone diacetate chemical structure, C25H31FO8, CAS 67-78-7
Triamcinolone diacetate
CAS 67-78-7C25H31FO8
Methandrostenolone chemical structure, C20H28O2, CAS 72-63-9
Methandrostenolone
CAS 72-63-9C20H28O2
Methylprednisolone chemical structure, C22H30O5, CAS 83-43-2
Methylprednisolone
CAS 83-43-2C22H30O5
Fluocortolone chemical structure, C22H29FO4, CAS 152-97-6
Fluocortolone
CAS 152-97-6C22H29FO4
Dexamethasone phosphate chemical structure, C22H30FO8P, CAS 312-93-6
Dexamethasone phosphate
CAS 312-93-6C22H30FO8P
Betamethasone chemical structure, C22H29FO5, CAS 378-44-9
Betamethasone
CAS 378-44-9C22H29FO5
Fluorometholone chemical structure, C22H29FO4, CAS 426-13-1
Fluorometholone
CAS 426-13-1C22H29FO4
Boldenone chemical structure, C19H26O2, CAS 846-48-0
Boldenone
CAS 846-48-0C19H26O2
Dexamethasone 17-acetate chemical structure, C24H31FO6, CAS 25122-35-4
Dexamethasone 17-acetate
CAS 25122-35-4C24H31FO6
Flumethasone chemical structure, C22H28F2O5, CAS 2135-17-3
Flumethasone
CAS 2135-17-3C22H28F2O5
Betamethasone valerate chemical structure, C27H37FO6, CAS 2152-44-5
Betamethasone valerate
CAS 2152-44-5C27H37FO6
2,17beta-Dihydroxy-17-methylandrosta-1,4-dien-3-one chemical structure, C20H28O3, CAS 2304-17-8
2,17beta-Dihydroxy-17-methylandrosta-1,4-dien-3-one
CAS 2304-17-8C20H28O3
Methylprednisolone succinate chemical structure, C26H34O8, CAS 2921-57-5
Methylprednisolone succinate
CAS 2921-57-5C26H34O8
Formebolone chemical structure, C21H28O4, CAS 2454-11-7
Formebolone
CAS 2454-11-7C21H28O4
17-Hydroxy-3-oxoestra-1,4-dien-10-yl acetate chemical structure, C20H26O4
17-Hydroxy-3-oxoestra-1,4-dien-10-yl acetate
C20H26O4
Beclomethasone chemical structure, C22H29ClO5, CAS 4419-39-0
Beclomethasone
CAS 4419-39-0C22H29ClO5
Beclomethasone dipropionate chemical structure, C28H37ClO7, CAS 5534-09-8
Beclomethasone dipropionate
CAS 5534-09-8C28H37ClO7