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Impurities and reference standards

Monoacetyldapsone

Also known as MADDS, N-Acetyldapsone, Acetyldapsone

CAS 565-20-8Formula C14H14N2O3SMolar mass 290.34 g/molEC 621-642-3
GHS signal word: Danger. Pictograms: Corrosive, Harmful or irritant 7 suppliers listed
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Monoacetyldapsone chemical structure, C14H14N2O3S, CAS 565-20-8
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
565-20-8
Formula
C14H14N2O3S
Molar mass
290.34 g/mol
EC number
621-642-3
HS code
293090
Category
Impurities and reference standards

What is Monoacetyldapsone?

Plain description, key identifiers and synonyms

Monoacetyldapsone is a secondary carboxamide resulting from acetylation of one of the amino groups of dapsone. It is an anilide, a secondary carboxamide, a member of acetamides and a sulfone. It is functionally related to a dapsone.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
N-[4-(4-aminophenyl)sulfonylphenyl]acetamide
CAS number
565-20-8 CAS number cross-checked
EC number
621-642-3
Molecular formula
C14H14N2O3S
UNII
A4YKS8ULCN
MDL number
MFCD00672496
InChIKey
WDOCBIHNYYQINH-UHFFFAOYSA-N
InChI
InChI=1S/C14H14N2O3S/c1-10(17)16-12-4-8-14(9-5-12)20(18,19)13-6-2-11(15)3-7-13/h2-9H,15H2,1H3,(H,16,17)
SMILES (canonical and isomeric)
CC(=O)NC1=CC=C(C=C1)S(=O)(=O)C2=CC=C(C=C2)N

Synonyms

  • MADDS
  • N-Acetyldapsone
  • Acetyldapsone
  • 4'-Sulfanilylacetanilide
  • monoacetyl dapsone
  • N-(4-((4-Aminophenyl)sulfonyl)phenyl)acetamide
  • Acetamide, N-(4-((4-aminophenyl)sulfonyl)phenyl)-
  • Acetamide, N-[4-[(4-aminophenyl)sulfonyl]phenyl]-
  • N-{4-[(4-aminophenyl)sulfonyl]phenyl}acetamide
  • N-(4-[(4-Aminophenyl)sulfonyl]phenyl)acetamide
  • N-[4-[(4-aminophenyl)sulfonyl]phenyl]acetamide
  • monoacetyl-diaminodiphenylsulfone
  • 4-acetamido-phenyl-4'-aminophenyl sulfone
  • N-Acetyl Dapsone
  • N-Monoacetyl-4,4'-diaminodiphenyl sulfone
  • N-[4-(4-aminophenyl)sulfonylphenyl]acetamide
  • N-Acetyl-4,4'-diaminodiphenylsulfone
  • N-Acetyldapsone, MADDS
  • Acetanilide, 4'-sulfanilyl-
  • N-Acetyl-4,4-diaminodiphenylsulfone
  • 4-(Acetamido)-4'-aminobiphenyl sulphone
  • N-[4-(4-aminobenzene-1-sulfonyl)phenyl]acetamide
  • Dapsone Impurity 14
  • monoacetyl-dapsone
  • 4'-sulfanilyl-acetanilid
Show all 32 synonyms
  • N-[4-(4-aminobenzenesulfonyl)phenyl]acetamide
  • Mono-N-acetyl dapsone
  • 3-13-00-01286 (Beilstein Handbook Reference)
  • N-[4-[(4-Aminophenyl)sulfonyl]phenyl]-acetamide
  • p-Sulfanilylacetanilide Acetamide
  • Dapsone Impurity 2Monoacetyl Dapsone
  • 4-Acetylamino-4'-aminodiphenyl sulfone

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
290.34 g/molcalc.
Exact mass
290.0725 Dacalc.
LogP (octanol/water)
2.06calc.
Topological polar surface area
89.26 Ųcalc.
Hydrogen bond donors
2calc.
Hydrogen bond acceptors
4calc.
Rotatable bonds
3calc.
Heavy atoms
20calc.
Rings
2calc.
Aromatic rings
2calc.
Fraction sp3 carbons
0.07calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=S(=O)(c1ccccc1)c1ccccc1

O=S(=O)(c1ccccc1)c1ccccc1

2 rings, 15 atoms, the Diphenyl sulfone ring system.

1,066 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS05: Corrosive
Corrosive
GHS07: Harmful or irritant
Harmful or irritant

Hazard statements

  • H315Causes skin irritation.
  • H317May cause an allergic skin reaction.
  • H318Causes serious eye damage.
  • H335May cause respiratory irritation.
Precautionary statements (18)
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P271Use only outdoors or in a well-ventilated area.
  • P272Contaminated work clothing should not be allowed out of the workplace.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P302 + P352If on skin: Wash with plenty of water.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P305 + P354 + P338If in eyes: Immediately rinse with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P317Get medical help.
  • P319Get medical help if you feel unwell.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P332 + P317If skin irritation occurs: Get medical help.
  • P333 + P317If skin irritation or rash occurs: Get medical help.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P403 + P233Store in a well-ventilated place. Keep container tightly closed.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Monoacetyldapsone suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 7 suppliers
7 of 7 offers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

7 suppliers in 5 countries

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Monoacetyldapsone price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

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Uses and applications

What the substance is used for, by industry and function

Pharmacological actions

  • Anti-Infective Agents

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Monoacetyldapsone is traded under.

HS 2930.90Indicative HS code

Organo-sulphur compounds, other

World exports in 2024
$5.83B
+0.1% vs 2023, imports $5.93B
2019 to 2024
Top exporters
  1. China40.7%
  2. United States10.9%
  3. Japan9.3%
Top importers
  1. United States13.3%
  2. Brazil12.6%
  3. China6.6%
Reported customs values in USD, not prices.Full trade data

The HS code shown for Monoacetyldapsone is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Monoacetyldapsone, based on the data on this page

What is Monoacetyldapsone?

Monoacetyldapsone is a secondary carboxamide resulting from acetylation of one of the amino groups of dapsone. It is an anilide, a secondary carboxamide, a member of acetamides and a sulfone. It is functionally related to a dapsone.

What is the CAS number of Monoacetyldapsone?

The CAS registry number of Monoacetyldapsone is 565-20-8.

What is the molecular formula and weight of Monoacetyldapsone?

The molecular formula of Monoacetyldapsone is C14H14N2O3S and its molar mass is 290.34 g/mol.

What is Monoacetyldapsone used for?

Known uses and roles of Monoacetyldapsone include anti-infective agents.

Is Monoacetyldapsone hazardous?

Monoacetyldapsone carries the GHS signal word "Danger". Main hazards: causes skin irritation, may cause an allergic skin reaction, causes serious eye damage. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Monoacetyldapsone?

Monoacetyldapsone is usually classified under HS code 293090 (Organo-sulphur compounds, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Monoacetyldapsone?

CompoundList lists 7 suppliers of Monoacetyldapsone in China, Australia, Canada, Czech Republic and 1 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Monoacetyldapsone?

Suppliers quote Monoacetyldapsone on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Monoacetyldapsone

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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