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Amines and amides

N-Hydroxyphthalimide

Also known as 2-Hydroxyphthalimide, 1H-Isoindole-1,3(2H)-dione, 2-hydroxy-, Phthalimide, N-hydroxy-

CAS 524-38-9Formula C8H5NO3Molar mass 163.13 g/molEC 208-358-1
GHS signal word: Warning. Pictograms: Harmful or irritant 28 suppliers listed
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N-Hydroxyphthalimide chemical structure, C8H5NO3, CAS 524-38-9
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
524-38-9
Formula
C8H5NO3
Molar mass
163.13 g/mol
EC number
208-358-1
HS code
292800
Category
Amines and amides

What is N-Hydroxyphthalimide?

Plain description, key identifiers and synonyms

N-Hydroxyphthalimide is a chemical substance with the molecular formula C8H5NO3 and a molar mass of 163.13 g/mol. Its CAS registry number is 524-38-9. The IUPAC name is 2-hydroxyisoindole-1,3-dione.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
2-hydroxyisoindole-1,3-dione
CAS number
524-38-9 CAS number cross-checkedOther or deprecated CAS: 3229-40-1
EC number
208-358-1
Molecular formula
C8H5NO3
UNII
BXI99M81X0
MDL number
MFCD00005891
InChIKey
CFMZSMGAMPBRBE-UHFFFAOYSA-N
InChI
InChI=1S/C8H5NO3/c10-7-5-3-1-2-4-6(5)8(11)9(7)12/h1-4,12H
SMILES (canonical and isomeric)
C1=CC=C2C(=C1)C(=O)N(C2=O)O

Synonyms

  • 2-Hydroxyphthalimide
  • 1H-Isoindole-1,3(2H)-dione, 2-hydroxy-
  • Phthalimide, N-hydroxy-
  • 2-hydroxyisoindoline-1,3-dione
  • 2-Hydroxy-1H-isoindole-1,3(2H)-dione
  • 2-hydroxyisoindole-1,3-dione
  • 2-hydroxy-2,3-dihydro-1H-isoindole-1,3-dione
  • 2-oxidanylisoindole-1,3-dione
  • 2-hydroxy-isoindole-1,3-dione
  • NHPI
  • Phthaloxime
  • 2-Hydroxyisoindolin-1,3-dione
  • N-Hydroxyphalimide
  • N-hydoxyphthalimide
  • N-hydroxyphtalimide
  • N-hydroxypthalimide
  • N-hyroxyphthalimide
  • N-hydroxy-phtalimide
  • N-hydroxylphthalimide
  • N-hydroxyphthalirnide
  • n-hydroxy phthalimide
  • N-hydroxy-phthalimide
  • N-(Hydroxy)phthalimide
  • N-Hydroxyphthalimide (NOP)
  • N-Hydroxyphthalimide, 97%
Show all 36 synonyms
  • 5-21-11-00100 (Beilstein Handbook Reference)
  • 1H-Isoindole-1, 2-hydroxy-
  • 2-hydroxy-1,3-isoindolinedione
  • Cfmzsmgampbrbe-uhfffaoysa-
  • 2-hydroxybenzo[c]azoline-1,3-dione
  • 1,2-Benzenedicarboximide, N-hydroxy-
  • 2-hydroxybenzo[c]azolidine-1,3-dione
  • 2-hydroxy-1H-isoindol-1,3(2H)-dione
  • 2-Hydroxy-1H-isoindole-1,3(2H)-dione #
  • N-Hydroxyphthalimide, purum, >=98.0% (T)
  • N-Hydroxyphthalimide, Vetec(TM) reagent grade, 97%

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
163.13 g/molcalc.
Exact mass
163.0269 Dacalc.
LogP (octanol/water)
0.67calc.
Topological polar surface area
57.61 Ųcalc.
Hydrogen bond donors
1calc.
Hydrogen bond acceptors
3calc.
Rotatable bonds
0calc.
Heavy atoms
12calc.
Rings
2calc.
Aromatic rings
1calc.
Fraction sp3 carbons
0calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C1NC(=O)c2ccccc21

O=C1NC(=O)c2ccccc21

2 rings, 11 atoms, the Phthalimide ring system.

2,700 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant

Hazard statements

  • H315Causes skin irritation.
  • H319Causes serious eye irritation.
  • H335May cause respiratory irritation.
Precautionary statements (16)
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P271Use only outdoors or in a well-ventilated area.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P302 + P352If on skin: Wash with plenty of water.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P319Get medical help if you feel unwell.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P332 + P317If skin irritation occurs: Get medical help.
  • P337 + P317If eye irritation persists: Get medical help.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P403 + P233Store in a well-ventilated place. Keep container tightly closed.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

N-Hydroxyphthalimide suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 28 suppliers
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Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

28 suppliers in 8 countries

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N-Hydroxyphthalimide price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Regulatory status

Inventories, regulations and trade controls that list this substance

United States

  • TSCA inventory (USA)
    Status: Active in US commerce

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code N-Hydroxyphthalimide is traded under.

HS 2928.00Indicative HS code

Organic derivatives of hydrazine or of hydroxylamine

World exports in 2024
$1.38B
−9.0% vs 2023, imports $1.52B
2019 to 2024
Top exporters
  1. Switzerland * partner reported44.0%
  2. China18.4%
  3. Italy9.4%
Top importers
  1. Brazil21.8%
  2. United States12.8%
  3. Italy10.8%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for N-Hydroxyphthalimide is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about N-Hydroxyphthalimide, based on the data on this page

What is N-Hydroxyphthalimide?

N-Hydroxyphthalimide is a chemical substance with the molecular formula C8H5NO3 and a molar mass of 163.13 g/mol. Its CAS registry number is 524-38-9. The IUPAC name is 2-hydroxyisoindole-1,3-dione.

What is the CAS number of N-Hydroxyphthalimide?

The CAS registry number of N-Hydroxyphthalimide is 524-38-9. Other or deprecated CAS numbers: 3229-40-1.

What is the molecular formula and weight of N-Hydroxyphthalimide?

The molecular formula of N-Hydroxyphthalimide is C8H5NO3 and its molar mass is 163.13 g/mol.

What is N-Hydroxyphthalimide used for?

Known uses and roles of N-Hydroxyphthalimide include building blocks in research and laboratory and screening compounds in research and laboratory.

Is N-Hydroxyphthalimide hazardous?

N-Hydroxyphthalimide carries the GHS signal word "Warning". Main hazards: causes skin irritation, causes serious eye irritation, may cause respiratory irritation. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of N-Hydroxyphthalimide?

N-Hydroxyphthalimide is usually classified under HS code 292800 (Organic derivatives of hydrazine or of hydroxylamine). This is indicative, confirm it with your customs broker before shipping.

Where can I buy N-Hydroxyphthalimide?

CompoundList lists 28 suppliers of N-Hydroxyphthalimide in China, United States, Canada, India and 4 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy N-Hydroxyphthalimide in India?

3 suppliers in India list N-Hydroxyphthalimide on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of N-Hydroxyphthalimide?

Suppliers quote N-Hydroxyphthalimide on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle N-Hydroxyphthalimide

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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