CompoundList
Sign in
Nucleosides and nucleotides

NADPH

Also known as TPNH, Dihydronicotinamide-adenine dinucleotide phosphate, Dihydrocodehydrogenase II

CAS 53-57-6Formula C21H30N7O17P3Molar mass 745.43 g/molEC 200-177-6
37 suppliers listed
Get quotes Compare 37 suppliers
NADPH chemical structure, C21H30N7O17P3, CAS 53-57-6
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
53-57-6
Formula
C21H30N7O17P3
Molar mass
745.43 g/mol
EC number
200-177-6
HS code
293499
Category
Nucleosides and nucleotides

What is NADPH?

Plain description, key identifiers and synonyms

NADPH is the reduced form of NADP+, used in anabolic reactions, such as lipid and nucleic acid synthesis, which require NADPH as a reducing agent. It has a role as a cofactor and a fundamental metabolite. It is a NAD(P)H and a NADP. It is a conjugate acid of a NADPH(4-).

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
[[(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-3-hydroxy-4-phosphonooxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [(2R,3S,4R,5R)-5-(3-carbamoyl-4H-pyridin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl hydrogen phosphate
CAS number
53-57-6 CAS number cross-checkedOther or deprecated CAS: 2646-71-1
EC number
200-177-6
Molecular formula
C21H30N7O17P3
UNII
381Q4X082D
MDL number
MFCD00036263, MFCD00674870
InChIKey
ACFIXJIJDZMPPO-NNYOXOHSSA-N
InChI
InChI=1S/C21H30N7O17P3/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(44-46(33,34)35)14(30)11(43-21)6-41-48(38,39)45-47(36,37)40-5-10-13(29)15(31)20(42-10)27-3-1-2-9(4-27)18(23)32/h1,3-4,7-8,10-11,13-16,20-21,29-31H,2,5-6H2,(H2,23,32)(H,36,37)(H,38,39)(H2,22,24,25)(H2,33,34,35)/t10-,11-,13-,14-,15-,16-,20-,21-/m1/s1
Canonical SMILES
NC(=O)C1=CN(C2OC(COP(=O)(O)OP(=O)(O)OCC3OC(n4cnc5c(N)ncnc54)C(OP(=O)(O)O)C3O)C(O)C2O)C=CC1
Isomeric SMILES
C1C=CN(C=C1C(=O)N)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)(O)OP(=O)(O)OC[C@@H]3[C@H]([C@H]([C@@H](O3)N4C=NC5=C(N=CN=C54)N)OP(=O)(O)O)O)O)O

Synonyms

  • TPNH
  • Dihydronicotinamide-adenine dinucleotide phosphate
  • Dihydrocodehydrogenase II
  • Reduced triphosphopyridine nucleotide
  • Reduced Nicotinamide Adenine Dinucleotide Phosphate
  • NADPH2
  • beta-NADPH
  • dihydronicotinamide adenine dinucleotide phosphate
  • reduced nicotinamide-adenine dinucleotide phosphate
  • Nicotinamide-adenine dinucleotide phosphate, reduced
  • Adenosine 5'-(trihydrogen diphosphate), 2'-(dihydrogen phosphate), P'-5'-ester with 1,4-dihydro-1-beta-D-ribofuranosyl-3-pyridinecarboxamide
  • reduced Coenzyme II
  • dihydronicotinamide adenine dinucleotide-P
  • nadph hydride
  • NADP-reduced
  • Reduced codehydrogenase ii
  • NADPH-sodium salt
  • reduced Cozymase II
  • beta-NADPH-D
  • b-NADPH
  • reduced Codehydrase II
  • beta-NADPH Tetrasodium
  • Nadp reduced fom
  • Coenzyme ii, reduced
  • Nadp reduced form
Show all 36 synonyms
  • Triphosphopyridine nucleotide reduced
  • beta-Nicotinamide Adenine Dinucleotide Phosphate Tetrasodium Salt
  • dihydrotriphosphopyridine nucleotide reduced
  • Nicotinamide-adenine-dinucleotide-phosphorate
  • b-Nicotinamide-adenine-dinucleotide-phosphorate
  • beta-Nicotinamide-adenine-dinucleotide-phosphorate
  • Nicotinamide-adenine-dinucleotide-phosphoric acid
  • reducednicotinamide-adenine dinucleotide phosphate
  • b-Nicotinamide-adenine-dinucleotide-phosphoric acid
  • Nicotinamide adenine dinucleotide phosphate - reduced
  • beta-Nicotinamide-adenine-dinucleotide-phosphoric acid

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
745.43 g/molcalc.
Exact mass
745.0911 Dacalc.
LogP (octanol/water)
-2.57calc.
Topological polar surface area
364.2 ร…ยฒcalc.
Hydrogen bond donors
9calc.
Hydrogen bond acceptors
18calc.
Rotatable bonds
13calc.
Heavy atoms
48calc.
Rings
5calc.
Aromatic rings
2calc.
Fraction sp3 carbons
0.52calc.
Formal charge
0calc.
Stereocentres
10calc.
Lipinski rule of five
Fails (3 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=[PH](OCC1CCC(N2C=CCC=C2)O1)O[PH](=O)OCC1CCC(n2cnc3cncnc32)O1

O=[PH](OCC1CCC(N2C=CCC=C2)O1)O[PH](=O)OCC1CCC(n2cnc3cncnc32)O1

5 rings, 34 atoms.

36 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

NADPH suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 37 suppliers
30 of 30 offers
  • Maintain Biotech Co., Ltd.
    China ManufacturerUnclaimed profile
    ฮฒ-nadphGrade, purity and minimum order on request
    Price on request
    View
  • 001Chemical
    China, HangzhouUnclaimed profile
    NADPHGrade, purity and minimum order on request
    Price on request
    View
  • 10X Chem
    United States, San DiegoUnclaimed profile
    NADPHGrade, purity and minimum order on request
    Price on request
    View
  • A2B Chem LLC
    United States, San DiegoUnclaimed profile
    NADPHGrade, purity and minimum order on request
    Price on request
    View
  • Aa Blocks LLC
    United States, San DiegoUnclaimed profile
    NADPHGrade, purity and minimum order on request
    Price on request
    View
  • AbaChemScene, LLC
    United States, Monmouth JunctionUnclaimed profile
    NADPHGrade, purity and minimum order on request
    Price on request
    View
  • ABCR GmbH & CO. KG
    GermanyUnclaimed profile
    NADPHGrade, purity and minimum order on request
    Price on request
    View
  • Accel Scientific S.L.
    Spain, BarcelonaUnclaimed profile
    NADPHGrade, purity and minimum order on request
    Price on request
    View
  • Accela ChemBio Inc.
    United States, San DiegoUnclaimed profile
    NADPHGrade, purity and minimum order on request
    Price on request
    View
  • ACTIVATE SCIENTIFIC GmbH
    GermanyUnclaimed profile
    NADPHGrade, purity and minimum order on request
    Price on request
    View

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

37 suppliers in 9 countries

Send one request to many suppliers

Choose up to 10 suppliers or let us match your request. Compare quotes side by side, free.

Choose suppliersPost a request

NADPH price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

Get latest price

Uses and applications

What the substance is used for, by industry and function

Roles

  • cofactor
  • fundamental metabolite
  • metabolite

Regulatory status

Inventories, regulations and trade controls that list this substance

United States

  • TSCA inventory (USA)
    Status: Inactive in US commerce

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code NADPH is traded under.

HS 2934.99Indicative HS code

Nucleic acids and their salts, other heterocyclic compounds, not elsewhere classified in heading 2934

World exports in 2024
$26.7B
+15.0% vs 2023, imports $26.3B
2019 to 2024
Top exporters
  1. Ireland26.3%
  2. China15.7%
  3. Singapore10.3%
Top importers
  1. United States24.5%
  2. Germany23.1%
  3. Japan4.5%
Reported customs values in USD, not prices.Full trade data

The HS code shown for NADPH is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about NADPH, based on the data on this page

What is NADPH?

NADPH is the reduced form of NADP+, used in anabolic reactions, such as lipid and nucleic acid synthesis, which require NADPH as a reducing agent. It has a role as a cofactor and a fundamental metabolite. It is a NAD(P)H and a NADP. It is a conjugate acid of a NADPH(4-).

What is the CAS number of NADPH?

The CAS registry number of NADPH is 53-57-6. Other or deprecated CAS numbers: 2646-71-1.

What is the molecular formula and weight of NADPH?

The molecular formula of NADPH is C21H30N7O17P3 and its molar mass is 745.43 g/mol.

What is NADPH used for?

Known uses and roles of NADPH include cofactor, fundamental metabolite and metabolite.

Is NADPH hazardous?

No GHS hazard classification for NADPH is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of NADPH?

NADPH is usually classified under HS code 293499 (Nucleic acids and their salts, whether or not chemically defined, other heterocyclicโ€ฆ). This is indicative, confirm it with your customs broker before shipping.

Where can I buy NADPH?

CompoundList lists 37 suppliers of NADPH in United States, China, Spain, Germany and 5 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of NADPH?

Suppliers quote NADPH on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle NADPH

Get quotes for NADPH

Post one free request with your grade, quantity and destination. Matching suppliers send quotes you can compare side by side.
Post a request Sell NADPH
Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
Embed this structure on your websiteShow code

Paste this code into your page to show the 2D structure of NADPH with a 3D view, its CAS number and a link back to this page. Free to use with the link kept.

<iframe src="https://www.compoundlist.com/embed/structure/nadph-53-57-6" title="NADPH structure on CompoundList" width="360" height="420" style="border:1px solid #E7E2DA;border-radius:12px;max-width:100%" loading="lazy" referrerpolicy="strict-origin-when-cross-origin"></iframe>
Preview the embed

Explore more in Nucleosides and nucleotides or HS code 293499

37 suppliers
Free quotes, contact stays private
Get quotes