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Naproxen sodium chemical structure, C14H13NaO3, CAS 26159-34-2
2D chemical structure

Key facts

What buyers check first

CAS number
26159-34-2
Formula
C14H13NaO3
Molar mass
252.25 g/mol
EC number
247-486-2
HS code
291899
Category
Analgesics and anti-inflammatories

What is Naproxen sodium?

Plain description, key identifiers and synonyms

Naproxen sodium is an organic sodium salt consisting of equimolar amounts of naproxen(1) anions and sodium anions. It has a role as a non-steroidal anti-inflammatory drug, a non-narcotic analgesic, an antipyretic, a cyclooxygenase 2 inhibitor and a cyclooxygenase 1 inhibitor. It contains a naproxen(1-).

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
sodium (2S)-2-(6-methoxynaphthalen-2-yl)propanoate
CAS number
26159-34-2 CAS number cross-checked
EC number
247-486-2
Molecular formula
C14H13NaO3
UNII
9TN87S3A3C
MDL number
MFCD00058507
InChIKey
CDBRNDSHEYLDJV-FVGYRXGTSA-M
InChI
InChI=1S/C14H14O3.Na/c1-9(14(15)16)10-3-4-12-8-13(17-2)6-5-11(12)7-10;/h3-9H,1-2H3,(H,15,16);/q;+1/p-1/t9-;/m0./s1
Canonical SMILES
COc1ccc2cc(C(C)C(=O)[O-])ccc2c1.[Na+]
Isomeric SMILES
C[C@@H](C1=CC2=C(C=C1)C=C(C=C2)OC)C(=O)[O-].[Na+]

Synonyms

  • Naprelan
  • Naproxen sodium salt
  • Miranax
  • Primeral
  • Naprium
  • Naprux
  • Diocodal
  • Prexan
  • Flanax
  • Anaprox ds
  • BAYH6689
  • Naproxen sodium anhydrous
  • Topcare all day pain relief
  • RS 3650
  • AnaDent
  • Belmora Flanax
  • Aleve Caplets
  • Aleve Gelcaps
  • Bayer Aleve
  • Careall Naproxen
  • Naproxen Caplets
  • Rapidol Naproxen
  • All Day Relief
  • Sodium, Naproxen
  • Medique Mediproxen
Show all 39 synonyms
  • Sodium Naproxenate
  • Aleve Liquid Gels
  • Naproxen Sodium DS
  • Naproxenate, Sodium
  • Aleve Headache Pain
  • Naproxen Pain Relief
  • All Day Pain Relief
  • Back and Muscle Pain
  • Naproxen sodium tablet
  • Rugby All Day Relief
  • Calmadol Pain Reliever
  • Equate Naproxen Sodium
  • Naproxen Headache Pain
  • Careone Naproxen Sodium

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
252.25 g/molcalc.
Exact mass
252.0762 Dacalc.
LogP (octanol/water)
-1.29calc.
Topological polar surface area
49.36 ร…ยฒcalc.
Hydrogen bond donors
0calc.
Hydrogen bond acceptors
3calc.
Rotatable bonds
3calc.
Heavy atoms
18calc.
Rings
2calc.
Aromatic rings
2calc.
Fraction sp3 carbons
0.21calc.
Formal charge
0calc.
Stereocentres
1calc.
Components
2calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccc2ccccc2c1

c1ccc2ccccc2c1

2 rings, 10 atoms, the Naphthalene ring system.

17,920 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS07: Harmful or irritant
Harmful or irritant
GHS08: Serious health hazard
Serious health hazard

Hazard statements

  • H302Harmful if swallowed.
  • H315Causes skin irritation.
  • H319Causes serious eye irritation.
  • H335May cause respiratory irritation.
  • H360May damage fertility or the unborn child.
Precautionary statements (21)
  • P203Obtain, read and follow all safety instructions before use.
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P270Do not eat, drink or smoke when using this product.
  • P271Use only outdoors or in a well-ventilated area.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P301 + P317If swallowed: Get medical help.
  • P302 + P352If on skin: Wash with plenty of water.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P318If exposed or concerned, get medical advice.
  • P319Get medical help if you feel unwell.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P330Rinse mouth.
  • P332 + P317If skin irritation occurs: Get medical help.
  • P337 + P317If eye irritation persists: Get medical help.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P403 + P233Store in a well-ventilated place. Keep container tightly closed.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Naproxen sodium suppliers

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Naproxen sodium price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Roles

  • analgesic
  • anti-inflammatory agent
  • anti-inflammatory drug
  • anti-ulcer drug
  • antipyretic
  • antirheumatic drug
  • cyclooxygenase 1 inhibitor
  • cyclooxygenase 2 inhibitor
  • enzyme inhibitor
  • gout suppressant
  • non-narcotic analgesic
  • non-steroidal anti-inflammatory drug
  • pharmaceutical

Pharmacology

Naproxen Sodium is the sodium salt form of naproxen, a member of the arylacetic acid group of non-steroidal anti-inflammatory drugs (NSAIDs) with anti-inflammatory analgesic and antipyretic properties. Naproxen sodium reversibly and competitively inhibits cyclooxygenases (COX), thereby blocking the conversion of arachidonic acid to pro-inflammatory prostaglandins. This inhibits the formation of prostaglandins that are involved in pain, inflammation and fever.

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • Active ingredient in FDA approved drug labels

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Naproxen sodium is traded under.

HS 2918.99Indicative HS code

Carboxylic acids, with additional oxygen function (not alcohol, phenol, aldehyde or ketone)โ€ฆ

World exports in 2024
$1.46B
โˆ’1.1% vs 2023, imports $1.54B
2019 to 2024
Top exporters
  1. China40.0%
  2. India * partner reported26.6%
  3. Germany8.0%
Top importers
  1. United States25.6%
  2. Brazil6.7%
  3. Argentina5.9%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Naproxen sodium is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Naproxen sodium, based on the data on this page

What is Naproxen sodium?

Naproxen sodium is an organic sodium salt consisting of equimolar amounts of naproxen(1) anions and sodium anions. It has a role as a non-steroidal anti-inflammatory drug, a non-narcotic analgesic, an antipyretic, a cyclooxygenase 2 inhibitor and a cyclooxygenase 1 inhibitor. It contains a naproxen(1-).

What is the CAS number of Naproxen sodium?

The CAS registry number of Naproxen sodium is 26159-34-2.

What is the molecular formula and weight of Naproxen sodium?

The molecular formula of Naproxen sodium is C14H13NaO3 and its molar mass is 252.25 g/mol.

What is Naproxen sodium used for?

Known uses and roles of Naproxen sodium include analgesics and antipyretics in pharmaceuticals, anti-inflammatories in pharmaceuticals, analgesic, anti-inflammatory agent, anti-inflammatory drug and 10 more.

Is Naproxen sodium hazardous?

Naproxen sodium carries the GHS signal word "Danger". Main hazards: harmful if swallowed, causes skin irritation, causes serious eye irritation. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Naproxen sodium?

Naproxen sodium is usually classified under HS code 291899 (Carboxylic acids with additional oxygen function and their anhydrides, halidesโ€ฆ). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Naproxen sodium?

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Where can I buy Naproxen sodium in India?

10 suppliers in India list Naproxen sodium on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Naproxen sodium?

Suppliers quote Naproxen sodium on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Naproxen sodium

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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