Naproxen sodium
Also known as Naprelan, Naproxen sodium salt, Miranax
Key facts
What buyers check first
- CAS number
- 26159-34-2
- Formula
- C14H13NaO3
- Molar mass
- 252.25 g/mol
- EC number
- 247-486-2
- HS code
- 291899
- Category
- Analgesics and anti-inflammatories
What is Naproxen sodium?
Plain description, key identifiers and synonyms
Naproxen sodium is an organic sodium salt consisting of equimolar amounts of naproxen(1) anions and sodium anions. It has a role as a non-steroidal anti-inflammatory drug, a non-narcotic analgesic, an antipyretic, a cyclooxygenase 2 inhibitor and a cyclooxygenase 1 inhibitor. It contains a naproxen(1-).
Identifiers
Registry numbers, names and line notations, tap to copy
- IUPAC name
- sodium (2S)-2-(6-methoxynaphthalen-2-yl)propanoate
- CAS number
- 26159-34-2 CAS number cross-checked
- EC number
- 247-486-2
- Molecular formula
- C14H13NaO3
- UNII
- 9TN87S3A3C
- MDL number
- MFCD00058507
- InChIKey
- CDBRNDSHEYLDJV-FVGYRXGTSA-M
- InChI
- InChI=1S/C14H14O3.Na/c1-9(14(15)16)10-3-4-12-8-13(17-2)6-5-11(12)7-10;/h3-9H,1-2H3,(H,15,16);/q;+1/p-1/t9-;/m0./s1
- Canonical SMILES
- COc1ccc2cc(C(C)C(=O)[O-])ccc2c1.[Na+]
- Isomeric SMILES
- C[C@@H](C1=CC2=C(C=C1)C=C(C=C2)OC)C(=O)[O-].[Na+]
Synonyms
- Naprelan
- Naproxen sodium salt
- Miranax
- Primeral
- Naprium
- Naprux
- Diocodal
- Prexan
- Flanax
- Anaprox ds
- BAYH6689
- Naproxen sodium anhydrous
- Topcare all day pain relief
- RS 3650
- AnaDent
- Belmora Flanax
- Aleve Caplets
- Aleve Gelcaps
- Bayer Aleve
- Careall Naproxen
- Naproxen Caplets
- Rapidol Naproxen
- All Day Relief
- Sodium, Naproxen
- Medique Mediproxen
Show all 39 synonymsShow fewer synonyms
- Sodium Naproxenate
- Aleve Liquid Gels
- Naproxen Sodium DS
- Naproxenate, Sodium
- Aleve Headache Pain
- Naproxen Pain Relief
- All Day Pain Relief
- Back and Muscle Pain
- Naproxen sodium tablet
- Rugby All Day Relief
- Calmadol Pain Reliever
- Equate Naproxen Sodium
- Naproxen Headache Pain
- Careone Naproxen Sodium
Physical and chemical properties
Measured values and descriptors computed from the structure
Physical and chemical properties
Measured values, check the supplier specification for your grade
No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.
Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.
Computed descriptors
Calculated from the structure, useful for screening and formulation
| Molecular weight | 252.25 g/molcalc.Computed value |
|---|---|
| Exact mass | 252.0762 Dacalc.Computed value |
| LogP (octanol/water) | -1.29calc.Computed value |
| Topological polar surface area | 49.36 ร
ยฒcalc.Computed value |
| Hydrogen bond donors | 0calc.Computed value |
| Hydrogen bond acceptors | 3calc.Computed value |
| Rotatable bonds | 3calc.Computed value |
| Heavy atoms | 18calc.Computed value |
| Rings | 2calc.Computed value |
| Aromatic rings | 2calc.Computed value |
| Fraction sp3 carbons | 0.21calc.Computed value |
| Formal charge | 0calc.Computed value |
| Stereocentres | 1calc.Computed value |
| Components | 2calc.Computed value |
| Lipinski rule of five | Passes (0 violations)calc.Computed value |
Calculated for screening. Confirm critical figures with the supplier.
Murcko scaffold
The ring system that remains when every side chain is removed
c1ccc2ccccc2c1
2 rings, 10 atoms, the Naphthalene ring system.
17,920 other chemicals share this scaffoldSafety and hazards
GHS classification summary, not a safety data sheet
Hazard statements
- H302Harmful if swallowed.
- H315Causes skin irritation.
- H319Causes serious eye irritation.
- H335May cause respiratory irritation.
- H360May damage fertility or the unborn child.
Precautionary statements (21)
- P203Obtain, read and follow all safety instructions before use.
- P261Avoid breathing dust, fume, gas, mist, vapours or spray.
- P264Wash skin thoroughly after handling.
- P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
- P270Do not eat, drink or smoke when using this product.
- P271Use only outdoors or in a well-ventilated area.
- P280Wear protective gloves, protective clothing, eye protection and face protection.
- P301 + P317If swallowed: Get medical help.
- P302 + P352If on skin: Wash with plenty of water.
- P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
- P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
- P318If exposed or concerned, get medical advice.
- P319Get medical help if you feel unwell.
- P321Specific treatment (see supplemental first aid instructions on the label).
- P330Rinse mouth.
- P332 + P317If skin irritation occurs: Get medical help.
- P337 + P317If eye irritation persists: Get medical help.
- P362 + P364Take off contaminated clothing. And wash it before reuse.
- P403 + P233Store in a well-ventilated place. Keep container tightly closed.
- P405Store locked up.
- P501Dispose of contents and container in accordance with local regulations.
GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.
Full safety data and first aidNaproxen sodium suppliers
Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings
- China, Changsha ManufacturerUnclaimed profileNaproxen SodiumGrade, purity and minimum order on requestPrice on request
- ChinaUnclaimed profileNaproxen SodiumGrade, purity and minimum order on requestPrice on request
- ChinaUnclaimed profileNaproxen SodiumGrade, purity and minimum order on requestPrice on request
- ChinaUnclaimed profileNaproxen SodiumGrade, purity and minimum order on requestPrice on request
- Pakistan ManufacturerUnclaimed profileNaproxen SodiumGrade, purity and minimum order on requestPrice on request
- China ManufacturerUnclaimed profileNaproxen SodiumGrade, purity and minimum order on requestPrice on request
- India, Chennai ManufacturerUnclaimed profileNaproxen sodiumGrade Pharma (USP)Price on request
- India, Sangareddy ManufacturerUnclaimed profileNaproxen sodiumGrade Pharma (USP)Price on request
- India, Sangareddy ManufacturerUnclaimed profileNaproxen sodiumGrade, purity and minimum order on requestPrice on request
- China, Taizhou ManufacturerUnclaimed profileNaproxen sodiumGrade Pharma (USP)Price on request
Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.
Where suppliers are based
96 suppliers in 20 countries
- United States32
- China22
- India10
- Germany4
- United Kingdom4
- Bangladesh3
- and 14 more countries
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Naproxen sodium price
Indicative price range per kg from live supplier offers
Suppliers quote this chemical on request. Send one free request and compare quotes side by side.
Uses and applications
What the substance is used for, by industry and function
Industries and functions
Roles
- analgesic
- anti-inflammatory agent
- anti-inflammatory drug
- anti-ulcer drug
- antipyretic
- antirheumatic drug
- cyclooxygenase 1 inhibitor
- cyclooxygenase 2 inhibitor
- enzyme inhibitor
- gout suppressant
- non-narcotic analgesic
- non-steroidal anti-inflammatory drug
- pharmaceutical
Pharmacology
Naproxen Sodium is the sodium salt form of naproxen, a member of the arylacetic acid group of non-steroidal anti-inflammatory drugs (NSAIDs) with anti-inflammatory analgesic and antipyretic properties. Naproxen sodium reversibly and competitively inhibits cyclooxygenases (COX), thereby blocking the conversion of arachidonic acid to pro-inflammatory prostaglandins. This inhibits the formation of prostaglandins that are involved in pain, inflammation and fever.
Regulatory status
Inventories, regulations and trade controls that list this substance
Health and food
- Active ingredient in FDA approved drug labels
HS code and trade data
Customs classification and reported world trade statistics
Global trade
World import and export statistics for the HS code Naproxen sodium is traded under.
Carboxylic acids, with additional oxygen function (not alcohol, phenol, aldehyde or ketone)โฆ
- United States25.6%
- Brazil6.7%
- Argentina5.9%
* Partner reported figures, a lower bound.
The HS code shown for Naproxen sodium is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.
Frequently asked questions
Quick answers about Naproxen sodium, based on the data on this page
What is Naproxen sodium?
What is the CAS number of Naproxen sodium?
What is the molecular formula and weight of Naproxen sodium?
What is Naproxen sodium used for?
Is Naproxen sodium hazardous?
What is the HS code of Naproxen sodium?
Where can I buy Naproxen sodium?
Where can I buy Naproxen sodium in India?
What is the price of Naproxen sodium?
Guides for buyers
Practical guides that help when you source, ship or handle Naproxen sodium
- Article, QualityPharma grades explained: IP vs BP vs USP vs EPWhat the Indian, British, US and European pharmacopoeias are, how their monographs differ, what multi grade claims mean and why a grade alone does not make a product fit for medicines.Read
- Guide, SafetyHow to read a safety data sheet in 10 minutesA section by section method to pull the essentials out of any 16 section SDS: identity, hazards, composition, storage, PPE, properties, transport and emergency measures.Read
- Guide, SafetyGHS pictograms, signal words and hazard statements explainedA practical guide to the nine GHS pictograms, the signal words Danger and Warning, H and P statements, and how to read a chemical label in seconds.Read
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