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Flavonoids and polyphenols

Naringenin

Also known as (S)-Naringenin, salipurpol, (2S)-Naringenin

CAS 480-41-1Formula C15H12O5Molar mass 272.26 g/molEC 207-550-2
GHS signal word: Warning. Pictograms: Harmful or irritant 68 suppliers listed
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Naringenin chemical structure, C15H12O5, CAS 480-41-1
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
480-41-1
Formula
C15H12O5
Molar mass
272.26 g/mol
EC number
207-550-2
HS code
293299
Category
Flavonoids and polyphenols

What is Naringenin?

Plain description, key identifiers and synonyms

(S)-naringenin is the (S)-enantiomer of naringenin. It has a role as a plant metabolite and an expectorant. It is a (2S)-flavan-4-one and a naringenin. It is a conjugate acid of a (S)-naringenin(1-). It is an enantiomer of a (R)-naringenin.

Naringenin is a main polyphenol in citrus fruit.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(2S)-5,7-dihydroxy-2-(4-hydroxyphenyl)-2,3-dihydrochromen-4-one
CAS number
480-41-1 CAS number cross-checkedOther or deprecated CAS: 13308-00-4
EC number
207-550-2
Molecular formula
C15H12O5
UNII
HN5425SBF2
MDL number
MFCD00870553
INCI name
NARINGENIN
InChIKey
FTVWIRXFELQLPI-ZDUSSCGKSA-N
InChI
InChI=1S/C15H12O5/c16-9-3-1-8(2-4-9)13-7-12(19)15-11(18)5-10(17)6-14(15)20-13/h1-6,13,16-18H,7H2/t13-/m0/s1
Canonical SMILES
O=C1CC(c2ccc(O)cc2)Oc2cc(O)cc(O)c21
Isomeric SMILES
C1[C@H](OC2=CC(=CC(=C2C1=O)O)O)C3=CC=C(C=C3)O

Synonyms

  • (S)-Naringenin
  • salipurpol
  • (2S)-Naringenin
  • Naringenine
  • Salipurol
  • naringetol
  • pelargidanon
  • 5,7,4'-Trihydroxyflavanone
  • (-)-(2S)-Naringenin
  • (S)-2,3-Dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
  • (2S)-5,7-dihydroxy-2-(4-hydroxyphenyl)-2,3-dihydrochromen-4-one
  • (S)-5,7-Dihydroxy-2-(4-hydroxyphenyl)chroman-4-one
  • Asahina
  • Narigenin
  • (-)-Naringenin
  • Flavanone, 4',5,7-trihydroxy-
  • 2,3-Dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
  • (2S)-5,7-dihydroxy-2-(4-hydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-4-one
  • 4H-1-Benzopyran-4-one, 2,3-dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-, (2S)-
  • (2S)-5,7-dihydroxy-2-(4-hydroxyphenyl)-2,3-dihydro-4H-chromen-4-one
  • 4H-1-Benzopyran-4-one,2,3-dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-, (2S)-
  • (2S)-5,7-dihydroxy-2-(4-hydroxyphenyl)chroman-4-one
  • s-naringenin
  • Nari
  • 2uxu
Show all 34 synonyms
  • 4deu
  • pelargidanon 1602
  • 4eh3
  • 4',5,7-triOH-Flavone
  • 4',5,7-Trihydroxyflavanon
  • Naringenin, (-)-
  • DivK1c_000118
  • 5,7,4'-trihydroxy flavanone
  • 4',5, 7-Trihydroxyflavanone

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
272.26 g/molcalc.
Exact mass
272.0685 Dacalc.
LogP (octanol/water)
2.51calc.
Topological polar surface area
86.99 Ųcalc.
Hydrogen bond donors
3calc.
Hydrogen bond acceptors
5calc.
Rotatable bonds
1calc.
Heavy atoms
20calc.
Rings
3calc.
Aromatic rings
2calc.
Fraction sp3 carbons
0.13calc.
Formal charge
0calc.
Stereocentres
1calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C1CC(c2ccccc2)Oc2ccccc21

O=C1CC(c2ccccc2)Oc2ccccc21

3 rings, 17 atoms, the Flavanone ring system.

742 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant

Hazard statements

  • H315Causes skin irritation.
  • H319Causes serious eye irritation.
Precautionary statements (9)
  • P264Wash skin thoroughly after handling.
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P302 + P352If on skin: Wash with plenty of water.
  • P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P332 + P317If skin irritation occurs: Get medical help.
  • P337 + P317If eye irritation persists: Get medical help.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Naringenin suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 68 suppliers
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Where suppliers are based

68 suppliers in 13 countries

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Naringenin price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

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Uses and applications

What the substance is used for, by industry and function

Cosmetic ingredient, INCI name NARINGENIN(skin conditioning)

Pharmacological actions

  • Anti-Ulcer Agents
  • Estrogen Antagonists

Roles

  • eukaryotic metabolite
  • expectorant
  • metabolite
  • pharmaceutical
  • plant metabolite

Functional uses

  • Softener and conditioner

Cosmetic functions

  • Skin conditioning

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • EU cosmetic ingredient inventory

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Naringenin is traded under.

HS 2932.99Indicative HS code

Heterocyclic compounds with oxygen hetero-atom(s) only, other

World exports in 2024
$3.81B
+10.3% vs 2023, imports $7.05B
2019 to 2024
Top exporters
  1. China28.9%
  2. Switzerland * partner reported12.7%
  3. Germany7.8%
Top importers
  1. United States49.7%
  2. China11.9%
  3. India * partner reported3.3%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Naringenin is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Naringenin, based on the data on this page

What is Naringenin?

(S)-naringenin is the (S)-enantiomer of naringenin. It has a role as a plant metabolite and an expectorant. It is a (2S)-flavan-4-one and a naringenin. It is a conjugate acid of a (S)-naringenin(1-). It is an enantiomer of a (R)-naringenin.

What is the CAS number of Naringenin?

The CAS registry number of Naringenin is 480-41-1. Other or deprecated CAS numbers: 13308-00-4.

What is the molecular formula and weight of Naringenin?

The molecular formula of Naringenin is C15H12O5 and its molar mass is 272.26 g/mol.

What is Naringenin used for?

Known uses and roles of Naringenin include skin conditioning agents in cosmetics and personal care, eukaryotic metabolite, expectorant, metabolite, pharmaceutical and 5 more.

Is Naringenin hazardous?

Naringenin carries the GHS signal word "Warning". Main hazards: causes skin irritation, causes serious eye irritation. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Naringenin?

Naringenin is usually classified under HS code 293299 (Heterocyclic compounds with oxygen hetero-atom(s) only, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Naringenin?

CompoundList lists 68 suppliers of Naringenin in United States, China, United Kingdom, Germany and 9 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Naringenin?

Suppliers quote Naringenin on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Naringenin

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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