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Nitric oxide chemical structure, NO, CAS 10102-43-9
2D chemical structure

Key facts

What buyers check first

Appearance
Colorless gas, blue liq
Melting point
-163.6 ยฐC
Boiling point
-151.7 ยฐC
Density
1.27 AT -150.2 ยฐC, LIQ
Solubility
7.38 ml/ 100 ml water at 0 ยฐC, 4.6 ml/ 100 ml water at 20 ยฐC, 2.37 ml/ 100 ml water at 6โ€ฆ
HS code
285390
Category
Industrial gases
UN number
UN 1660
Illustrative photo, a gas cylinder on a trolley on a laboratory bench
Typical packagingIllustrative packaging image, not the actual product

What is Nitric oxide?

Plain description, key identifiers and synonyms

Nitric oxide is a nitrogen oxide which is a free radical, each molecule of which consists of one nitrogen and one oxygen atom. It has a role as a neurotransmitter, a bronchodilator agent, a vasodilator agent, a radical scavenger, a signalling molecule, a mouse metabolite, an Escherichia coli metabolite and a human metabolite. It is a nitrogen oxide, an inorganic radical and a member of reactive nitrogen species.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
nitric oxide
CAS number
10102-43-9 CAS number cross-checked
EC number
233-271-0
Molecular formula
NO
UNII
31C4KY9ESH
InChIKey
MWUXSHHQAYIFBG-UHFFFAOYSA-N
InChI
InChI=1S/NO/c1-2
SMILES (canonical and isomeric)
[N]=O

Synonyms

  • nitrogen monoxide
  • Mononitrogen monoxide
  • INOmax
  • Nitrosyl radical
  • Amidogen, oxo-
  • Nitrogen oxide (NO)
  • nitrogen monooxide
  • Nitric oxide trimer
  • Inovent
  • oxyde nitrique
  • RCRA waste number P076
  • Nitrogen(II) oxide
  • EDRF
  • Genosyl
  • Oxide, Nitric
  • Monoxide, Nitrogen
  • Monoxide, Mononitrogen
  • Endogenous Nitrate Vasodilator
  • Nitrate Vasodilator, Endogenous
  • Vasodilator, Endogenous Nitrate
  • Endothelium-Derived Nitric Oxide
  • Nitric Oxide, Endothelium Derived
  • Nitric Oxide, Endothelium-Derived
  • nitroso
  • Ulspira
Show all 38 synonyms
  • Ntric Oxide
  • NOW st
  • Noxivent 101
  • Noxivent 102
  • Noxivent
  • Nitric Oxide, Glutathione
  • Nitric Oxide, Zinc, Glutathione
  • Nitric Oxide, Vitamin D3, Zinc
  • Nitric Oxide, Zinc, Vitamin D3
  • Nitric Oxide, Sophoricoside, Zinc
  • Nitric Oxide, Vitamin D3, Glutathione
  • Nitric Oxide, Zinc, N-Acetylglucosamine
  • NO DENTAL CARE (Improves gum disease, gum health, breath)

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
Colorless gas, blue liqexp.
Odour
Sharp, sweet odorexp.
Melting point
-163.6 ยฐCexp.
Boiling point
-151.7 ยฐCexp.
Density
1.27 AT -150.2 ยฐC, LIQexp.
Solubility
7.38 ml/ 100 ml water at 0 ยฐC, 4.6 ml/ 100 ml water at 20 ยฐC, 2.37 ml/ 100 ml water at 60 ยฐCexp.
Vapour pressure
45600 MM HG AT -94.8 ยฐCexp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
30.01 g/molcalc.
Exact mass
29.998 Dacalc.
LogP (octanol/water)
-0.45calc.
Topological polar surface area
39.37 ร…ยฒcalc.
Hydrogen bond donors
0calc.
Hydrogen bond acceptors
1calc.
Rotatable bonds
0calc.
Heavy atoms
2calc.
Rings
0calc.
Aromatic rings
0calc.
Fraction sp3 carbons
0calc.
Formal charge
0calc.
Stereocentres
0calc.

Calculated for screening. Confirm critical figures with the supplier.

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS03: Oxidiser
Oxidiser
GHS04: Gas under pressure
Gas under pressure
GHS05: Corrosive
Corrosive
GHS06: Acute toxicity (severe)
Acute toxicity (severe)
GHS08: Serious health hazard
Serious health hazard
000OXNFPA 704 rating

Hazard statements

  • H270May cause or intensify fire, oxidiser.
  • H280Contains gas under pressure, may explode if heated.
  • H314Causes severe skin burns and eye damage.
  • H318Causes serious eye damage.
  • H330Fatal if inhaled.
  • H331Toxic if inhaled.
  • H373May cause damage to organs through prolonged or repeated exposure.
Precautionary statements (25)
  • P220Keep away from clothing and other combustible materials.
  • P244Keep valves and fittings free from oil and grease.
  • P260Do not breathe dust, fume, gas, mist, vapours or spray.
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P271Use only outdoors or in a well-ventilated area.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P284In case of inadequate ventilation wear respiratory protection.
  • P301 + P330 + P331If swallowed: Rinse mouth. Do not induce vomiting.
  • P302 + P361 + P354If on skin: Take off immediately all contaminated clothing. Immediately rinse with water for several minutes.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P305 + P354 + P338If in eyes: Immediately rinse with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P316Get emergency medical help immediately.
  • P317Get medical help.
  • P319Get medical help if you feel unwell.
  • P320Specific treatment is urgent (see supplemental first aid instructions on the label).
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P363Wash contaminated clothing before reuse.
  • P370 + P376In case of fire: Stop leak if safe to do so.
  • P403Store in a well-ventilated place.
  • P403 + P233Store in a well-ventilated place. Keep container tightly closed.
  • P405Store locked up.
  • P410 + P403Protect from sunlight. Store in a well-ventilated place.
  • P501Dispose of contents and container in accordance with local regulations.
UN number
UN 1660
Transport hazard class
2.3

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Nitric oxide suppliers

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Nitric oxide price

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Uses and applications

What the substance is used for, by industry and function

Manufacture of nitric acid, in bleaching of rayon, stabilizer for propylene, methyl ether.

To prepare nitrosyl carbonyls.

Pharmacological actions

  • Bronchodilator Agents
  • Endothelium-Dependent Relaxing Factors
  • Free Radical Scavengers
  • Gasotransmitters
  • Neurotransmitter Agents

Roles

  • Escherichia coli metabolite
  • anti-anaemic agent
  • anti-inflammatory agent
  • anti-ulcer drug
  • antifibrotic agent
  • antifungal agent
  • antifungal drug
  • antihypertensive agent
  • antiinfective agent
  • antileishmanial agent
  • antimalarial
  • antimicrobial agent
  • antineoplastic agent
  • antiviral agent
  • bronchodilator agent
  • cardiovascular drug
  • human metabolite
  • mouse metabolite
  • neuroprotective agent
  • neurotransmitter
  • radical scavenger
  • renoprotective agent
  • signalling molecule
  • vasodilator agent

Pharmacology

Nitric oxide is a Vasodilator. The physiologic effect of nitric oxide is by means of Vasodilation.

How it is made

Prepared industrially by passing air through electric arc (basis of atmospheric nitrogen fixation) or by oxidation of ammonia over platinum gauze.

Oxidation of ammonia above 500 ยฐC, decomposition of nitrous oxide solution

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • Active ingredient in FDA approved drug labels

United States

  • TSCA inventory (USA)
    Status: Active in US commerce

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Nitric oxide is traded under.

HS 2853.90Indicative HS code

Phosphides, whether or not chemically defined, excluding ferrophosphorus, other, other

World exports in 2024
$2.45B
โˆ’33.6% vs 2023, imports $816M
2019 to 2024
Top exporters
  1. China68.4%
  2. Israel8.1%
  3. United States4.9%
Top importers
  1. United States19.3%
  2. Japan17.9%
  3. China13.4%
Reported customs values in USD, not prices.Full trade data

The HS code shown for Nitric oxide is indicative (it is known at chapter level only). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Nitric oxide, based on the data on this page

What is Nitric oxide?

Nitric oxide is a nitrogen oxide which is a free radical, each molecule of which consists of one nitrogen and one oxygen atom.

What is the CAS number of Nitric oxide?

The CAS registry number of Nitric oxide is 10102-43-9.

What is the molecular formula and weight of Nitric oxide?

The molecular formula of Nitric oxide is NO and its molar mass is 30.01 g/mol.

What is Nitric oxide used for?

Manufacture of nitric acid, in bleaching of rayon, stabilizer for propylene, methyl ether. To prepare nitrosyl carbonyls.

Is Nitric oxide hazardous?

Nitric oxide carries the GHS signal word "Danger". Main hazards: may cause or intensify fire, oxidiser, contains gas under pressure, may explode if heated, causes severe skin burns and eye damage. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Nitric oxide?

Nitric oxide is usually classified under HS code 285390 (Phosphides, whether or not chemically defined, excluding ferrophosphorus, otherโ€ฆ). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Nitric oxide?

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What is the price of Nitric oxide?

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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