Nps-2143 (CAS 284035-33-2): price, suppliers and safety

What is Nps-2143?

Plain description, key identifiers and synonyms

Nps-2143 is a chemical substance with the molecular formula C24H25ClN2O2 and a molar mass of 408.93 g/mol. Its CAS registry number is 284035-33-2. The IUPAC name is 2-chloro-6-[(2R)-2-hydroxy-3-[(2-methyl-1-naphthalen-2-ylpropan-2-yl)amino]propoxy]benzonitrile.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name: 2-chloro-6-[(2R)-2-hydroxy-3-[(2-methyl-1-naphthalen-2-ylpropan-2-yl)amino]propoxy]benzonitrile
CAS number: 284035-33-2 CAS number cross-checked
Molecular formula: C₂₄H₂₅ClN₂O₂
UNII: Z25PJ77W7V
MDL number: MFCD04113010
InChIKey: PZUJQWHTIRWCID-HXUWFJFHSA-N
InChI: InChI=1S/C24H25ClN2O2/c1-24(2,13-17-10-11-18-6-3-4-7-19(18)12-17)27-15-20(28)16-29-23-9-5-8-22(25)21(23)14-26/h3-12,20,27-28H,13,15-16H2,1-2H3/t20-/m1/s1
Canonical SMILES: CC(C)(Cc1ccc2ccccc2c1)NCC(O)COc1cccc(Cl)c1C#N
Isomeric SMILES: CC(C)(CC1=CC2=CC=CC=C2C=C1)NC[C@H](COC3=C(C(=CC=C3)Cl)C#N)O

Synonyms

NPS 2143
(+)-NPS-2143
2-chloro-6-[(2R)-2-hydroxy-3-{[2-methyl-1-(naphthalen-2-yl)propan-2-yl]amino}propoxy]benzonitrile
2-chloro-6-[(2R)-2-hydroxy-3-[(2-methyl-1-naphthalen-2-ylpropan-2-yl)amino]propoxy]benzonitrile
Benzonitrile, 2-chloro-6-((2R)-3-((1,1-dimethyl-2-(2-naphthalenyl)ethyl)amino)-2-hydroxypropoxy)-
Benzonitrile, 2-chloro-6-[(2R)-3-[[1,1-dimethyl-2-(2-naphthalenyl)ethyl]amino]-2-hydroxypropoxy]-
2-chloro-6-((2R)-2-hydroxy-3-((2-methyl-1-(naphthalen-2-yl)propan-2-yl)amino)propoxy)benzonitrile
2-chloro-6-((2R)-2-hydroxy-3-((2-methyl-1-naphthalen-2-ylpropan-2-yl)amino)propoxy)benzonitrile
2-Chloro-6-[(2R)-3-[[1,1-dimethyl-2-(2-naphthalenyl)ethyl]amino]-2-hydroxypropoxy]benzonitrile
(R)-2-chloro-6-(2-hydroxy-3-((2-methyl-1-(naphthalen-2-yl)propan-2-yl)amino)propoxy)benzonitrile
NPS-2143(SB 262470A )
(R)-2-chloro-6-(2-hydroxy-3-(2-methyl-1-(naphthalen-2-yl)propan-2-ylamino)propoxy)benzonitrile
2-Chloro-6-[((2R)-3-([1,1-dimethyl-2-(2-naphthalenyl)ethyl]-amino)-2-hydroxypropyl)oxy]benzonitrile hydrochloride
2-Chloro-6-[(R)-3-(1,1-dimethyl-2-naphthalen-2-yl-ethylamino)-2-hydroxy-propoxy]-benzonitrile

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight	408.93 g/molcalc.
Exact mass	408.1605 Dacalc.
LogP (octanol/water)	4.72calc.
Topological polar surface area	65.28 Å²calc.
Hydrogen bond donors	2calc.
Hydrogen bond acceptors	4calc.
Rotatable bonds	8calc.
Heavy atoms	29calc.
Rings	3calc.
Aromatic rings	3calc.
Fraction sp3 carbons	0.29calc.
Formal charge	0calc.
Stereocentres	1calc.
Lipinski rule of five	Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

c1ccc(OCCCNCCc2ccc3ccccc3c2)cc1

3 rings, 23 atoms.

3 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Nps-2143 suppliers

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Nps-2143 price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Industries and functions

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Nps-2143 is traded under.

HS 2926.90Indicative HS code

Nitrile-function compounds, other

World exports in 2024

$2.15B

−13.5% vs 2023, imports $2.17B

2019 to 2024

Top exporters

China35.6%
France * partner reported12.7%
India * partner reported11.2%

Top importers

United States13.6%
China12.4%
Brazil11.9%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Nps-2143 is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Parent and salt forms, stereoisomers, similar structures and isomers

Salt and hydrate forms

Records that share this compound as their parent

NPS-2143 hydrochloride chemical structure, C24H26Cl2N2O2, CAS 324523-20-8

NPS-2143 hydrochloride324523-20-8C₂₄H₂₆Cl₂N₂O₂

Similar structures

Nearest neighbours by Morgan fingerprint Tanimoto similarity

Benzenepropanoic acid, 3-cyano-4-[(2R)-3-[[1,1-dimethyl-2-(2-naphthalenyl)ethyl]amino]-2-hydroxypropoxy]-, (Hydrochloride) (1:1) chemical structure, C27H31ClN2O4, CAS 1192845-63-8

Same formula isomers

Different compounds that share this molecular formula

All isomers

4-[[4-(3-Chlorophenyl)piperazin-1-yl]methyl]-6,7,8,9-tetrahydrobenzo[g]chromen-2-one chemical structure, C24H25ClN2O2, CAS 850827-64-4

4-[[4-(3-Chlorophenyl)piperazin-1-yl]methyl]-6,7,8,9-tetrahydrobenzo[g]chromen-2-one850827-64-4C₂₄H₂₅ClN₂O₂1 supplier

11-(2-Chlorophenyl)-10-pentanoyl-2,3,4,5,10,11-hexahydro-1H-dibenzo[b,e][1,4]diazepin-1-one chemical structure, C24H25ClN2O2, CAS 362503-73-9

11-(2-Chlorophenyl)-10-pentanoyl-2,3,4,5,10,11-hexahydro-1H-dibenzo[b,e][1,4]diazepin-1-one362503-73-9C₂₄H₂₅ClN₂O₂

N-(8-Chloro-2,3,4,9-tetrahydro-1H-carbazol-1-yl)-4-phenyltetrahydro-2H-pyran-4-carboxamide chemical structure, C24H25ClN2O2, CAS 1574300-09-6

N-(8-Chloro-2,3,4,9-tetrahydro-1H-carbazol-1-yl)-4-phenyltetrahydro-2H-pyran-4-carboxamide1574300-09-6C₂₄H₂₅ClN₂O₂

6-(4-Chlorophenyl)-9,9-dimethyl-5-propanoyl-6,8,10,11-tetrahydrobenzo[b][1,4]benzodiazepin-7-one chemical structure, C24H25ClN2O2, CAS 333746-29-5

6-(4-Chlorophenyl)-9,9-dimethyl-5-propanoyl-6,8,10,11-tetrahydrobenzo[b][1,4]benzodiazepin-7-one333746-29-5C₂₄H₂₅ClN₂O₂

Para-chlorofuranylfentanyl chemical structure, C24H25ClN2O2, CAS 2748496-77-5

Para-chlorofuranylfentanyl2748496-77-5C₂₄H₂₅ClN₂O₂

para-Chloro furanyl fentanyl 3-furancarboxamide chemical structure, C24H25ClN2O2, CAS 2749618-77-5

para-Chloro furanyl fentanyl 3-furancarboxamide2749618-77-5C₂₄H₂₅ClN₂O₂

6-Chloro-7-methyl-4-({4-[(2E)-3-phenylprop-2-en-1-yl]piperazin-1-yl}methyl)-2H-chromen-2-one chemical structure, C24H25ClN2O2, CAS 899405-00-6

6-Chloro-7-methyl-4-({4-[(2E)-3-phenylprop-2-en-1-yl]piperazin-1-yl}methyl)-2H-chromen-2-one899405-00-6C₂₄H₂₅ClN₂O₂

(4-(1H-Pyrrol-1-yl)phenyl)(4-(((4-chlorobenzyl)oxy)methyl)piperidin-1-yl)methanone chemical structure, C24H25ClN2O2, CAS 1396685-10-1

(4-(1H-Pyrrol-1-yl)phenyl)(4-(((4-chlorobenzyl)oxy)methyl)piperidin-1-yl)methanone1396685-10-1C₂₄H₂₅ClN₂O₂

[4-(4-Chlorophenyl)-4-hydroxypiperidino](2-isopropyl-4-quinolyl)methanone chemical structure, C24H25ClN2O2, CAS 1144498-68-9

[4-(4-Chlorophenyl)-4-hydroxypiperidino](2-isopropyl-4-quinolyl)methanone1144498-68-9C₂₄H₂₅ClN₂O₂

Isoquinoline, 1,2,3,4-tetrahydro-3-benzylimino-6,7-dimethoxy-1-phenyl-, hydrochloride, hydrate (2:2:1) chemical structure, C24H25ClN2O2, CAS 78915-27-2

Isoquinoline, 1,2,3,4-tetrahydro-3-benzylimino-6,7-dimethoxy-1-phenyl-, hydrochloride, hydrate (2:2:1)78915-27-2C₂₄H₂₅ClN₂O₂

1-(4-Chlorophenyl)-N-(2-(7-methyl-2-oxo-1,2-dihydroquinolin-3-yl)ethyl)cyclopentanecarboxamide chemical structure, C24H25ClN2O2, CAS 851405-20-4

1-(4-Chlorophenyl)-N-(2-(7-methyl-2-oxo-1,2-dihydroquinolin-3-yl)ethyl)cyclopentanecarboxamide851405-20-4C₂₄H₂₅ClN₂O₂

2(1H)-Quinolinone, 3,4-dihydro-6-(4-(4-(4-chlorophenyl)-3,6-dihydro-1(2H)-pyridinyl)-1-oxobutyl)- chemical structure, C24H25ClN2O2, CAS 80834-72-6

2(1H)-Quinolinone, 3,4-dihydro-6-(4-(4-(4-chlorophenyl)-3,6-dihydro-1(2H)-pyridinyl)-1-oxobutyl)-80834-72-6C₂₄H₂₅ClN₂O₂

Frequently asked questions

Quick answers about Nps-2143, based on the data on this page

What is Nps-2143?

Nps-2143 is a chemical substance with the molecular formula C24H25ClN2O2 and a molar mass of 408.93 g/mol. Its CAS registry number is 284035-33-2. The IUPAC name is 2-chloro-6-[(2R)-2-hydroxy-3-[(2-methyl-1-naphthalen-2-ylpropan-2-yl)amino]propoxy]benzonitrile.

What is the CAS number of Nps-2143?

The CAS registry number of Nps-2143 is 284035-33-2.

What is the molecular formula and weight of Nps-2143?

The molecular formula of Nps-2143 is C24H25ClN2O2 and its molar mass is 408.93 g/mol.

What is Nps-2143 used for?

Known uses and roles of Nps-2143 include building blocks in research and laboratory and screening compounds in research and laboratory.

Is Nps-2143 hazardous?

No GHS hazard classification for Nps-2143 is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Nps-2143?

Nps-2143 is usually classified under HS code 292690 (Nitrile-function compounds, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Nps-2143?

Post a free request on CompoundList and suppliers of Nps-2143 will send you quotes. Your contact details stay private until you accept a quote.

What is the price of Nps-2143?

Suppliers quote Nps-2143 on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Nps-2143

Nps-2143

Key facts

What is Nps-2143?

Identifiers

Synonyms

Physical and chemical properties

Physical and chemical properties

Computed descriptors

Murcko scaffold

Safety and hazards

Nps-2143 suppliers

Nps-2143 price

Uses and applications

Industries and functions

Regulatory status

HS code and trade data

Global trade

Frequently asked questions

What is Nps-2143?

What is the CAS number of Nps-2143?

What is the molecular formula and weight of Nps-2143?

What is Nps-2143 used for?

Is Nps-2143 hazardous?

What is the HS code of Nps-2143?

Where can I buy Nps-2143?

What is the price of Nps-2143?

Guides for buyers

Get quotes for Nps-2143

Key facts

What is Nps-2143?

Identifiers

Synonyms

Physical and chemical properties

Physical and chemical properties

Computed descriptors

Murcko scaffold

Safety and hazards

Nps-2143 suppliers

Nps-2143 price

Uses and applications

Industries and functions

Regulatory status

HS code and trade data

Global trade

Related chemicals

Salt and hydrate forms

Similar structures

Same formula isomers

Frequently asked questions

What is Nps-2143?

What is the CAS number of Nps-2143?

What is the molecular formula and weight of Nps-2143?

What is Nps-2143 used for?

Is Nps-2143 hazardous?

What is the HS code of Nps-2143?

Where can I buy Nps-2143?

What is the price of Nps-2143?

Guides for buyers

Get quotes for Nps-2143