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Pharmaceuticals and APIs

Ospemifene

Also known as Osphena, FC-1271a, senshio

CAS 128607-22-7Formula C24H23ClO2Molar mass 378.90 g/molEC 664-452-6
GHS signal word: Warning. Pictograms: Hazardous to the environment 32 suppliers listed Drug substance
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Ospemifene chemical structure, C24H23ClO2, CAS 128607-22-7
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
128607-22-7
Formula
C24H23ClO2
Appearance
Crystals from ethanol + water
Solubility
Soluble in methanol
HS code
290949
Category
Pharmaceuticals and APIs
Illustrative photo, a shrink wrapped pallet of kraft paper sacks in a chemical plant
Typical packagingIllustrative packaging image, not the actual product

What is Ospemifene?

Plain description, key identifiers and synonyms

Ospemifene is an organochlorine compound that is a selective estrogen receptor modulator, used for treatment of dyspareunia. It has a role as an antineoplastic agent, an estrogen receptor modulator and an anti-inflammatory agent. It is a primary alcohol, an aromatic ether and an organochlorine compound. It derives from a hydride of a stilbene.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
2-[4-[(Z)-4-chloro-1,2-diphenylbut-1-enyl]phenoxy]ethanol
CAS number
128607-22-7 CAS number cross-checked
EC number
664-452-6
Molecular formula
C24H23ClO2
UNII
B0P231ILBK
MDL number
MFCD00871890
InChIKey
LUMKNAVTFCDUIE-VHXPQNKSSA-N
InChI
InChI=1S/C24H23ClO2/c25-16-15-23(19-7-3-1-4-8-19)24(20-9-5-2-6-10-20)21-11-13-22(14-12-21)27-18-17-26/h1-14,26H,15-18H2/b24-23-
Canonical SMILES
OCCOc1ccc(C(=C(CCCl)c2ccccc2)c2ccccc2)cc1
Isomeric SMILES
C1=CC=C(C=C1)/C(=C(/C2=CC=CC=C2)\C3=CC=C(C=C3)OCCO)/CCCl

Synonyms

  • Osphena
  • FC-1271a
  • senshio
  • Deamino-hydroxytoremifene
  • Fc-1271
  • Tore iii
  • 2-(4-(4-chloro-1,2-diphenyl-but-1-enyl)phenoxy)ethanol
  • 2-(p-((Z)-4-Chloro-1,2-diphenyl-1-butenyl)phenoxy)ethanol
  • Ospemifeno
  • (deaminohydroxy) toremifene
  • Z-2-(4-(4-chloro-1,2-diphenyl-but-1-enyl)phenoxy)ethanol
  • 2-{4-[(1Z)-4-chloro-1,2-diphenylbut-1-en-1-yl]phenoxy}ethanol
  • ospemifenum
  • 2-(4-((1Z)-4-chloro-1,2-diphenylbut-1-en-1-yl)phenoxy)ethanol
  • 2-(4-((Z)-4-chloro-1,2-di(phenyl)but-1-enyl)phenoxy)ethanol
  • 2-[4-[(Z)-4-chloro-1,2-di(phenyl)but-1-enyl]phenoxy]ethanol
  • Ethanol, 2-[4-[(1Z)-4-chloro-1,2-diphenyl-1-buten-1-yl]phenoxy]-
  • 2-[4-[(Z)-4-chloro-1,2-diphenylbut-1-enyl]phenoxy]ethanol
  • Ethanol, 2-[4-[(1Z)-4-chloro-1,2-diphenyl-1-butenyl]phenoxy]-
  • C24H23ClO2
  • (deaminohydroxy)toremifene
  • Ophena
  • Ethanol, 2-(4-((1Z)-4-chloro-1,2-diphenyl-1-butenyl)phenoxy)-
  • Osphena (TN)
  • Ospemifene (INN/USAN/BAN)
Show all 28 synonyms
  • 2-[4-[(1Z)-4-Chloro-1,2-diphenyl-1-buten-1-yl]phenoxy]ethanol
  • 2-{4-[(1Z)-4-chloro-1,2-diphenylbut-1-en-1-yl]phenoxy}ethan-1-ol
  • 2-[4-[(Z)-4-chloro-1,2-diphenyl-but-1-enyl]phenoxy]ethanol

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
Crystals from ethanol + waterexp.
Solubility
Soluble in methanolexp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
378.90 g/molcalc.
Exact mass
378.1387 Dacalc.
LogP (octanol/water)
5.65calc.
Topological polar surface area
29.46 Ųcalc.
Hydrogen bond donors
1calc.
Hydrogen bond acceptors
2calc.
Rotatable bonds
8calc.
Heavy atoms
27calc.
Rings
3calc.
Aromatic rings
3calc.
Fraction sp3 carbons
0.17calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (1 violation)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, C(=C(c1ccccc1)c1ccccc1)c1ccccc1

C(=C(c1ccccc1)c1ccccc1)c1ccccc1

3 rings, 20 atoms, the Triphenylethylene ring system.

482 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS09: Hazardous to the environment
Hazardous to the environment

Hazard statements

  • H400Very toxic to aquatic life.
  • H410Very toxic to aquatic life with long lasting effects.
Precautionary statements (3)
  • P273Avoid release to the environment.
  • P391Collect spillage.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Ospemifene suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 32 suppliers
30 of 30 offers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

32 suppliers in 10 countries

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Ospemifene price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Roles

  • anti-inflammatory agent
  • antineoplastic agent
  • estrogen receptor modulator
  • pharmaceutical

Pharmacology

Ospemifene is an Estrogen Agonist/Antagonist. The mechanism of action of ospemifene is as a Selective Estrogen Receptor Modulator.

How it is made

Preparation: R. J. Toivola et al., European Patent Office patent 95875 (1986 to Farmos).

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • Active ingredient in FDA approved drug labels

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Ospemifene is traded under.

HS 2909.49Indicative HS code

Ether-alcohols and their halogenated not elsewhere classified in subheading 2909.4

World exports in 2024
$1.74B
+6.8% vs 2023, imports $1.86B
2019 to 2024
Top exporters
  1. Germany20.6%
  2. China13.9%
  3. Netherlands12.2%
Top importers
  1. China8.8%
  2. Germany8.3%
  3. United States7.5%
Reported customs values in USD, not prices.Full trade data

The HS code shown for Ospemifene is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Ospemifene, based on the data on this page

What is Ospemifene?

Ospemifene is an organochlorine compound that is a selective estrogen receptor modulator, used for treatment of dyspareunia. It has a role as an antineoplastic agent, an estrogen receptor modulator and an anti-inflammatory agent. It is a primary alcohol, an aromatic ether and an organochlorine compound.

What is the CAS number of Ospemifene?

The CAS registry number of Ospemifene is 128607-22-7.

What is the molecular formula and weight of Ospemifene?

The molecular formula of Ospemifene is C24H23ClO2 and its molar mass is 378.90 g/mol.

What is Ospemifene used for?

Known uses and roles of Ospemifene include anti-inflammatory agent, antineoplastic agent, estrogen receptor modulator and pharmaceutical.

Is Ospemifene hazardous?

Ospemifene carries the GHS signal word "Warning". Main hazards: very toxic to aquatic life, very toxic to aquatic life with long lasting effects. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Ospemifene?

Ospemifene is usually classified under HS code 290949 (Ether-alcohols and their halogenated, sulphonated, nitrated or nitrosated derivatives…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Ospemifene?

CompoundList lists 32 suppliers of Ospemifene in China, United States, India, Germany and 6 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Ospemifene in India?

4 suppliers in India list Ospemifene on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Ospemifene?

Suppliers quote Ospemifene on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Ospemifene

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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