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Hormones and steroids

Toremifene

Also known as Acapodene, Farestone, Toremifeno

CAS 89778-26-7Formula C26H28ClNOMolar mass 405.97 g/molEC 618-298-1
8 suppliers listed Drug substance
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Toremifene chemical structure, C26H28ClNO, CAS 89778-26-7
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
89778-26-7
Formula
C26H28ClNO
Molar mass
405.97 g/mol
EC number
618-298-1
HS code
292229
Category
Hormones and steroids

What is Toremifene?

Plain description, key identifiers and synonyms

Toremifene is a tertiary amine, an aromatic ether and an organochlorine compound. It has a role as an antineoplastic agent, a bone density conservation agent, an estrogen receptor modulator and an estrogen antagonist. It derives from a hydride of a stilbene.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
2-[4-[(Z)-4-chloro-1,2-diphenylbut-1-enyl]phenoxy]-N,N-dimethylethanamine
CAS number
89778-26-7 CAS number cross-checkedOther or deprecated CAS: 275360-73-1
EC number
618-298-1
Molecular formula
C26H28ClNO
UNII
7NFE54O27T
MDL number
MFCD00801070
InChIKey
XFCLJVABOIYOMF-QPLCGJKRSA-N
InChI
InChI=1S/C26H28ClNO/c1-28(2)19-20-29-24-15-13-23(14-16-24)26(22-11-7-4-8-12-22)25(17-18-27)21-9-5-3-6-10-21/h3-16H,17-20H2,1-2H3/b26-25-
Canonical SMILES
CN(C)CCOc1ccc(C(=C(CCCl)c2ccccc2)c2ccccc2)cc1
Isomeric SMILES
CN(C)CCOC1=CC=C(C=C1)/C(=C(/CCCl)\C2=CC=CC=C2)/C3=CC=CC=C3

Synonyms

  • Acapodene
  • Farestone
  • Toremifeno
  • Toremifenum
  • Chlortamoxifen
  • Toremiphene
  • GTx-006
  • (Z)-2-(4-(4-Chloro-1,2-diphenyl-1-butenyl)phenoxy)-N,N-dimethylethanamine
  • (2-{4-[(1Z)-4-chloro-1,2-diphenylbut-1-en-1-yl]phenoxy}ethyl)dimethylamine
  • Ethanamine, 2-(4-(4-chloro-1,2-diphenyl-1-butenyl)phenoxy)-N,N-dimethyl-, (Z)-
  • Ethanamine, 2-(4-((1Z)-4-chloro-1,2-diphenyl-1-buten-1-yl)phenoxy)-N,N-dimethyl-
  • (2-(4-((1Z)-4-chloro-1,2-diphenylbut-1-en-1-yl)phenoxy)ethyl)dimethylamine
  • 2-(4-((Z)-4-chloro-1,2-di(phenyl)but-1-enyl)phenoxy)-N,N-dimethylethanamine
  • 2-[4-[(Z)-4-chloro-1,2-di(phenyl)but-1-enyl]phenoxy]-N,N-dimethylethanamine
  • (Z)-4-Chloro-1,2-diphenyl-1(4-(2-(N,N-dimethylamino)ethoxy)phenyl)-1-butene
  • Toremifene Base
  • Toremifene (INN)
  • 2-[4-[(Z)-4-chloro-1,2-diphenylbut-1-enyl]phenoxy]-N,N-dimethylethanamine
  • Z-Toremifene
  • Ethanamine, 2-(4-((1Z)-4-chloro-1,2-diphenyl-1-butenyl)phenoxy)-N,N-dimethyl-
  • 2-{4-[(1Z)-4-chloro-1,2-diphenylbut-1-en-1-yl]phenoxy}-N,N-dimethylethanamine
  • GTx 006
  • Estrimex
  • 2-{4-[(1Z)-4-chloro-1,2-diphenylbut-1-en-1-yl]phenoxy}-N,N-dimethylethan-1-amine
  • 89778-26-7 (free base)
Show all 28 synonyms
  • 2-(para-((Z)-4-Chloro-1,2-diphenyl-1-butenyl)phenoxy)-N,N-dimethylethylamine (IUPAC)
  • Toremifene impurity 01
  • Toremifene(GTx 006)

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
405.97 g/molcalc.
Exact mass
405.1859 Dacalc.
LogP (octanol/water)
6.22calc.
Topological polar surface area
12.47 Ųcalc.
Hydrogen bond donors
0calc.
Hydrogen bond acceptors
2calc.
Rotatable bonds
9calc.
Heavy atoms
29calc.
Rings
3calc.
Aromatic rings
3calc.
Fraction sp3 carbons
0.23calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (1 violation)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, C(=C(c1ccccc1)c1ccccc1)c1ccccc1

C(=C(c1ccccc1)c1ccccc1)c1ccccc1

3 rings, 20 atoms, the Triphenylethylene ring system.

482 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Toremifene suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 8 suppliers
8 of 8 offers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

8 suppliers in 3 countries

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Toremifene price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

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Uses and applications

What the substance is used for, by industry and function

Use classes: Pharmaceuticals.

Pharmacological actions

  • Antineoplastic Agents, Hormonal
  • Bone Density Conservation Agents
  • Selective Estrogen Receptor Modulators

Roles

  • antagonist
  • antimicrobial agent
  • antineoplastic agent
  • antiviral agent
  • bone density conservation agent
  • estrogen antagonist
  • estrogen receptor modulator
  • hormone antagonist
  • hormone receptor modulator
  • pharmaceutical
  • receptor modulator

Functional uses

  • Pharmaceutical

Pharmacology

Toremifene is an Estrogen Agonist/Antagonist. The mechanism of action of toremifene is as a Selective Estrogen Receptor Modulator.

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • Active ingredient in FDA approved drug labels

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Toremifene is traded under.

HS 2922.29Indicative HS code

Amino-naphthols and other amino-phenols, other than those containing more than one kind…

World exports in 2024
$467M
−15.3% vs 2023, imports $454M
2019 to 2024
Top exporters
  1. China63.1%
  2. India * partner reported15.5%
  3. Japan4.0%
Top importers
  1. India * partner reported25.8%
  2. United States14.4%
  3. South Korea7.6%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Toremifene is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Toremifene, based on the data on this page

What is Toremifene?

Toremifene is a tertiary amine, an aromatic ether and an organochlorine compound. It has a role as an antineoplastic agent, a bone density conservation agent, an estrogen receptor modulator and an estrogen antagonist. It derives from a hydride of a stilbene.

What is the CAS number of Toremifene?

The CAS registry number of Toremifene is 89778-26-7. Other or deprecated CAS numbers: 275360-73-1.

What is the molecular formula and weight of Toremifene?

The molecular formula of Toremifene is C26H28ClNO and its molar mass is 405.97 g/mol.

What is Toremifene used for?

Use classes: Pharmaceuticals.

Is Toremifene hazardous?

No GHS hazard classification for Toremifene is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Toremifene?

Toremifene is usually classified under HS code 292229 (Amino-naphthols and other amino-phenols, other than those containing more than one kind…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Toremifene?

CompoundList lists 8 suppliers of Toremifene in United States, China and Hong Kong. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Toremifene?

Suppliers quote Toremifene on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Toremifene

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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