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Screening compounds

Oxsi-2

Also known as Syk Inhibitor, 1H-Indole-5-sulfonamide, 2,3-dihydro-3-((1-methyl-1H-indol-3-yl)methylene)-2-oxo-, 1H-Indole-5-sulfonamide, 2,3-dihydro-3-((1-methyl-1H-indol-3-yl)methylene)-2-oxo-, (3Z)-

CAS 1956296-96-0Formula C18H15N3O3SMolar mass 353.40 g/mol
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Oxsi-2 chemical structure, C18H15N3O3S, CAS 1956296-96-0
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
1956296-96-0
Formula
C18H15N3O3S
Molar mass
353.40 g/mol
HS code
293590
Category
Screening compounds

What is Oxsi-2?

Plain description, key identifiers and synonyms

3-[(1-methyl-3-indolyl)methylidene]-2-oxo-1H-indole-5-sulfonamide is a member of indoles.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(3Z)-3-[(1-methylindol-3-yl)methylidene]-2-oxo-1H-indole-5-sulfonamide
CAS number
1956296-96-0Other or deprecated CAS: 622387-85-3
Molecular formula
C18H15N3O3S
UNII
5YZ3QBQ97C
MDL number
MFCD07776820
InChIKey
MLKHXLFEYOOYEY-NVNXTCNLSA-N
InChI
InChI=1S/C18H15N3O3S/c1-21-10-11(13-4-2-3-5-17(13)21)8-15-14-9-12(25(19,23)24)6-7-16(14)20-18(15)22/h2-10H,1H3,(H,20,22)(H2,19,23,24)/b15-8-
Canonical SMILES
Cn1cc(C=C2C(=O)Nc3ccc(S(N)(=O)=O)cc32)c2ccccc21
Isomeric SMILES
CN1C=C(C2=CC=CC=C21)/C=C\3/C4=C(C=CC(=C4)S(=O)(=O)N)NC3=O

Synonyms

  • Syk Inhibitor
  • 1H-Indole-5-sulfonamide, 2,3-dihydro-3-((1-methyl-1H-indol-3-yl)methylene)-2-oxo-
  • 1H-Indole-5-sulfonamide, 2,3-dihydro-3-((1-methyl-1H-indol-3-yl)methylene)-2-oxo-, (3Z)-
  • 2,3-Dihydro-3-((1-methyl-1H-indol-3-yl)methylene)-2-oxo-1H-indole-5-sulfonamide
  • (3Z)-3-[(1-methyl-1H-indol-3-yl)methylidene]-2-oxo-2,3-dihydro-1H-indole-5-sulfonamide
  • (3Z)-3-((1-methyl-1H-indol-3-yl)methylidene)-2-oxo-2,3-dihydro-1H-indole-5-sulfonamide
  • 2,3-Dihydro-3-[(1-methyl-1H-indol-3-yl)methylene]-2-oxo-1H-indole-5-sulfonamide
  • Spleen Tyrosine Kinase Inhibitor
  • (3Z)-3-[(1-methylindol-3-yl)methylidene]-2-oxo-1H-indole-5-sulfonamide
  • Syk Inhibitor OXSI-2
  • HSCI1_000356
  • Sdccgsbi-0086712.p003
  • 3-((1-methyl-1H-indol-3-yl)methylene)-2-oxoindoline-5-sulfonamide
  • (3Z)-3-[(1-methylindol-3-yl)methylene]-2-oxo-indoline-5-sulfonamide
  • 3-(1-Methylindol-3-ylmethylene)-2-oxo-2,3-dihydroindole-5-sulfonic acid amide
  • 3-[1-(1-Methyl-1H-indol-3-yl)-meth-(Z)-ylidene]-2-oxo-2,3-dihydro-1H-indole-5-sulfonic acid amide

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
353.40 g/molcalc.
Exact mass
353.0834 Dacalc.
LogP (octanol/water)
2.32calc.
Topological polar surface area
94.19 Ųcalc.
Hydrogen bond donors
2calc.
Hydrogen bond acceptors
3calc.
Rotatable bonds
2calc.
Heavy atoms
25calc.
Rings
4calc.
Aromatic rings
3calc.
Fraction sp3 carbons
0.06calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C1Nc2ccccc2C1=Cc1c[nH]c2ccccc12

O=C1Nc2ccccc2C1=Cc1c[nH]c2ccccc12

4 rings, 20 atoms, the 3-((1H-Indol-3-yl)methylene)indolin-2-one ring system.

29 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Oxsi-2 suppliers

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Oxsi-2 price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Pharmacology

SYK Inhibitor is any agent that inhibits the enzyme spleen tyrosine kinase (SYK).

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Oxsi-2 is traded under.

HS 2935.90Indicative HS code

Sulphonamides, other

World exports in 2024
$5.64B
−11.0% vs 2023, imports $8.56B
2019 to 2024
Top exporters
  1. Ireland43.1%
  2. China12.0%
  3. India * partner reported9.5%
Top importers
  1. United States23.6%
  2. Slovenia19.1%
  3. Spain11.7%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Oxsi-2 is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Oxsi-2, based on the data on this page

What is Oxsi-2?

3-[(1-methyl-3-indolyl)methylidene]-2-oxo-1H-indole-5-sulfonamide is a member of indoles.

What is the CAS number of Oxsi-2?

The CAS registry number of Oxsi-2 is 1956296-96-0. Other or deprecated CAS numbers: 622387-85-3.

What is the molecular formula and weight of Oxsi-2?

The molecular formula of Oxsi-2 is C18H15N3O3S and its molar mass is 353.40 g/mol.

What is Oxsi-2 used for?

Known uses and roles of Oxsi-2 include building blocks in research and laboratory and screening compounds in research and laboratory.

Is Oxsi-2 hazardous?

No GHS hazard classification for Oxsi-2 is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Oxsi-2?

Oxsi-2 is usually classified under HS code 293590 (Sulphonamides, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Oxsi-2?

Post a free request on CompoundList and suppliers of Oxsi-2 will send you quotes. Your contact details stay private until you accept a quote.

What is the price of Oxsi-2?

Suppliers quote Oxsi-2 on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Oxsi-2

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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