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Analgesics and anti-inflammatories

Oxycodone safety data

GHS hazards, precautions, first aid, handling and transport for Oxycodone. A classification summary, not a safety data sheet.
CAS 76-42-6Formula C18H21NO4
Narcotic drug

Oxycodone is prohibited on CompoundList. Listings, quotes and messages are disabled. This page is kept for information only.

Listing and enquiries are not allowed for this substance.

Reference: UN Single Convention on Narcotic Drugs 1961, HS 2022 subheading 2939.11 (opium alkaloids and their derivatives)

Our policy on controlled substances

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

GHS classification

Pictograms, signal word and hazard classes of the GHS classification

GHS07: Harmful or irritant
Harmful or irritant
GHS08: Serious health hazard
Serious health hazard
Signal word
Warning

Hazard classes and categories

  • Acute Tox. 4 (oral)
  • STOT SE 3 (narcotic effects)
  • Repr. 2
  • Lact.

Hazard statements

H codes grouped by type. Percentages show the share of classification notifications that report the statement

Health hazards

  • H302Harmful if swallowed.
  • H336May cause drowsiness or dizziness.
  • H361dSuspected of damaging the unborn child.
  • H361fdSuspected of damaging fertility. Suspected of damaging the unborn child.
  • H362May cause harm to breast-fed children.

Precautionary statements

P codes for prevention, response, storage and disposal

Prevention

  • P203Obtain, read and follow all safety instructions before use.
  • P260Do not breathe dust, fume, gas, mist, vapours or spray.
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P263Avoid contact during pregnancy and while nursing.
  • P264Wash skin thoroughly after handling.
  • P270Do not eat, drink or smoke when using this product.
  • P271Use only outdoors or in a well-ventilated area.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.

Response

  • P301 + P317If swallowed: Get medical help.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P318If exposed or concerned, get medical advice.
  • P319Get medical help if you feel unwell.
  • P330Rinse mouth.

Storage

  • P403 + P233Store in a well-ventilated place. Keep container tightly closed.
  • P405Store locked up.

Disposal

  • P501Dispose of contents and container in accordance with local regulations.

Handling, storage and disposal

Summaries only, follow the supplier SDS for your grade

Safe handling

Eye/face protection: Safety glasses with side-shields conforming to EN166. Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). /Oxycodone hydrochloride/ Skin protection: Handle with gloves. /Oxycodone hydrochloride/

Storage

Keep container tightly closed in a dry and well-ventilated place. /Oxycodone hydrochloride/ Oxycodone hydrochloride preparations should be stored in tight containers and generally should be protected from light and stored at 15-30 °C

Disposal

SRP: Expired or waste pharmaceuticals shall carefully take into consideration applicable DEA, EPA, and FDA regulations. It is not appropriate to dispose by flushing the pharmaceutical down the toilet or discarding to trash. If possible return the pharmaceutical to the manufacturer for proper disposal being careful to properly label and securely package the material. Alternatively, the waste pharmaceutical shall be labeled, securely packaged and transported by a state licensed medical waste contractor to dispose by burial in a licensed hazardous or toxic waste landfill or incinerator. Product: Offer surplus and non-recyclable solutions to a licensed disposal company. Contact a licensed professional waste disposal service to dispose of this material.

Exposure limits and toxicity

Occupational exposure limits and toxicity data

Oxycodone is a full opioid agonist and is relatively selective for the mu-opioid receptor, although it can bind to other opioid receptors at higher doses. The principal therapeutic action of oxycodone is analgesia. Acute overdose can be manifested by respiratory depression, somnolence progressing to stupor or coma, skeletal muscle flaccidity, cold and clammy skin, constricted pupils, and, in some cases, pulmonary edema, bradycardia, hypotension, partial or complete airway obstruction, atypical snoring, and death. Marked mydriasis rather than miosis may be seen with hypoxia in overdose situations. Both tolerance and physical dependence can develop during chronic opioid therapy.

Supplier safety data sheets

SDS documents uploaded by suppliers who list this chemical

No supplier has uploaded an SDS for Oxycodone yet.

Safety questions

Quick answers about handling Oxycodone safely

Is Oxycodone hazardous?

Oxycodone carries the GHS signal word "Warning". Main hazards: harmful if swallowed, may cause drowsiness or dizziness, suspected of damaging the unborn child. This summary is not an SDS, always read the supplier safety data sheet.

Which GHS pictograms apply to Oxycodone?

The GHS classification of Oxycodone shows 2 pictograms: GHS07 (harmful or irritant), GHS08 (serious health hazard).

How should Oxycodone be stored?

Keep container tightly closed in a dry and well-ventilated place. /Oxycodone hydrochloride/ Oxycodone hydrochloride preparations should be stored in tight containers and generally should be protected from light and stored at 15-30 °C

Where can I get the SDS for Oxycodone?

Ask the supplier for the safety data sheet of the exact grade you buy. Suppliers on CompoundList can attach their SDS to listings and send it with a quote. This page is a GHS classification summary, not an SDS.

GHS classification summary, not an SDS. Always check the supplier's SDS. Last updated 7 Oct 2026. Report an error