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Amines and amides

Phosphoethanolamine

Also known as O-Phosphorylethanolamine, 2-Aminoethyl dihydrogen phosphate, O-Phosphoethanolamine

CAS 1071-23-4Formula C2H8NO4PMolar mass 141.06 g/molEC 213-988-5
GHS signal word: Danger. Pictograms: Corrosive 46 suppliers listed
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Phosphoethanolamine chemical structure, C2H8NO4P, CAS 1071-23-4
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
1071-23-4
Formula
C2H8NO4P
Molar mass
141.06 g/mol
EC number
213-988-5
HS code
292119
Category
Amines and amides

What is Phosphoethanolamine?

Plain description, key identifiers and synonyms

O-phosphoethanolamine is the ethanolamine mono-ester of phosphoric acid, and a metabolite of phospholipid metabolism. This phosphomonoester shows strong structural similarity to the inhibitory neurotransmitter GABA, and is decreased in post-mortem Alzheimer's disease brain. It has a role as a mouse metabolite, a human metabolite and an algal metabolite. It is a phosphoethanolamine and a primary amino compound. It is a conjugate acid of an O-phosphonatoethanaminium(1-).

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
2-aminoethyl dihydrogen phosphate
CAS number
1071-23-4 CAS number cross-checked
EC number
213-988-5
Molecular formula
C2H8NO4P
UNII
78A2BX7AEU
MDL number
MFCD00008178
InChIKey
SUHOOTKUPISOBE-UHFFFAOYSA-N
InChI
InChI=1S/C2H8NO4P/c3-1-2-7-8(4,5)6/h1-3H2,(H2,4,5,6)
SMILES (canonical and isomeric)
C(COP(=O)(O)O)N

Synonyms

  • O-Phosphorylethanolamine
  • 2-Aminoethyl dihydrogen phosphate
  • O-Phosphoethanolamine
  • Phosphorylethanolamine
  • Colamine phosphate
  • ethanolamine phosphate
  • Ethanolamine O-phosphate
  • Phosphonoethanolamine
  • Phosphorylcolamine
  • Mono(2-aminoethyl) phosphate
  • Colamine phosphoric acid
  • Colaminphosphoric acid
  • (2-aminoethoxy)phosphonic acid
  • monoaminoethyl phosphate
  • 2-amino-ethanol phosphate
  • Ethanolamine acid phosphate
  • Ethanol, 2-amino-, dihydrogen phosphate (ester)
  • phosphoryl-ethanolamine
  • 2-amino-ethanol dihydrogen phosphate
  • phosphoric acid 2-aminoethyl phenyl ester
  • O-phosphonatoethanaminium
  • 2-azaniumylethyl hydrogen phosphate
  • 2-ammonioethyl phosphate
  • 2-azaniumylethyl phosphate
  • O-Phosphocolamine
Show all 38 synonyms
  • Phosphoryethanolamine
  • Ethanol, 2-amino-, phosphate
  • Colaminephosphoric acid
  • 2-Aminoethyl phosphate
  • OPE
  • Phosphoric acid, 2-aminoethyl phenyl ester
  • 2-Aminoethanol O-phosphate
  • Phosphoric acid mono-(2-amino-ethyl) ester
  • Colamine acid phosphate
  • EAP
  • Ethanol, 2-amino-, 1-(dihydrogen phosphate)
  • Ethamp
  • Ethanol, phosphate

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
141.06 g/molcalc.
Exact mass
141.0191 Dacalc.
LogP (octanol/water)
-0.95calc.
Topological polar surface area
92.78 Ųcalc.
Hydrogen bond donors
3calc.
Hydrogen bond acceptors
3calc.
Rotatable bonds
3calc.
Heavy atoms
8calc.
Rings
0calc.
Aromatic rings
0calc.
Fraction sp3 carbons
1calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS05: Corrosive
Corrosive

Hazard statements

  • H314Causes severe skin burns and eye damage.
  • H318Causes serious eye damage.
Precautionary statements (14)
  • P260Do not breathe dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P301 + P330 + P331If swallowed: Rinse mouth. Do not induce vomiting.
  • P302 + P361 + P354If on skin: Take off immediately all contaminated clothing. Immediately rinse with water for several minutes.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P305 + P354 + P338If in eyes: Immediately rinse with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P316Get emergency medical help immediately.
  • P317Get medical help.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P363Wash contaminated clothing before reuse.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Phosphoethanolamine suppliers

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All 46 suppliers
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Where suppliers are based

46 suppliers in 10 countries

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Phosphoethanolamine price

Indicative price range per kg from live supplier offers

No published prices right now

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Uses and applications

What the substance is used for, by industry and function

Roles

  • algal metabolite
  • animal metabolite
  • antineoplastic agent
  • eukaryotic metabolite
  • human metabolite
  • mammalian metabolite
  • metabolite
  • mouse metabolite
  • pharmaceutical

Pharmacology

Phosphorylethanolamine is a monophosphate ethanolamine ester that is an intermediate in the biosynthesis of sphingomyelins.

Regulatory status

Inventories, regulations and trade controls that list this substance

United States

  • TSCA inventory (USA)
    Status: Active in US commerce

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Phosphoethanolamine is traded under.

HS 2921.19Indicative HS code

Acyclic monoamines and their derivatives, salts thereof, other

World exports in 2024
$1.21B
+4.0% vs 2023, imports $1.16B
2019 to 2024
Top exporters
  1. China35.5%
  2. United States17.9%
  3. Germany16.4%
Top importers
  1. United States14.1%
  2. South Korea9.7%
  3. Japan8.4%
Reported customs values in USD, not prices.Full trade data

The HS code shown for Phosphoethanolamine is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Phosphoethanolamine, based on the data on this page

What is Phosphoethanolamine?

O-phosphoethanolamine is the ethanolamine mono-ester of phosphoric acid, and a metabolite of phospholipid metabolism. This phosphomonoester shows strong structural similarity to the inhibitory neurotransmitter GABA, and is decreased in post-mortem Alzheimer's disease brain.

What is the CAS number of Phosphoethanolamine?

The CAS registry number of Phosphoethanolamine is 1071-23-4.

What is the molecular formula and weight of Phosphoethanolamine?

The molecular formula of Phosphoethanolamine is C2H8NO4P and its molar mass is 141.06 g/mol.

What is Phosphoethanolamine used for?

Known uses and roles of Phosphoethanolamine include building blocks in research and laboratory, algal metabolite, animal metabolite, antineoplastic agent, eukaryotic metabolite and 5 more.

Is Phosphoethanolamine hazardous?

Phosphoethanolamine carries the GHS signal word "Danger". Main hazards: causes severe skin burns and eye damage, causes serious eye damage. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Phosphoethanolamine?

Phosphoethanolamine is usually classified under HS code 292119 (Acyclic monoamines and their derivatives, salts thereof, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Phosphoethanolamine?

CompoundList lists 46 suppliers of Phosphoethanolamine in China, United States, Japan, United Kingdom and 6 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Phosphoethanolamine?

Suppliers quote Phosphoethanolamine on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Phosphoethanolamine

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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