CompoundList
Sign in
Heterocyclic compounds

Piperic acid

Also known as (E,E)-piperic acid, Piperonic acid, Piperinic Acid

CAS 136-72-1Formula C12H10O4Molar mass 218.21 g/molEC 226-118-4
1 supplier listed
Get quotes See the supplier
Piperic acid chemical structure, C12H10O4, CAS 136-72-1
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
136-72-1
Formula
C12H10O4
Molar mass
218.21 g/mol
EC number
226-118-4
HS code
293299
Category
Heterocyclic compounds

What is Piperic acid?

Plain description, key identifiers and synonyms

(E,E)-piperic acid is a monocarboxylic acid that is (E)-penta-2,4-dienoic acid substituted by a 1,3-benzodioxol-5-yl group at position 5. It has been isolated from black pepper (Piper nigrum). It has a role as a plant metabolite. It is a member of benzodioxoles and an alpha,beta-unsaturated monocarboxylic acid. It is functionally related to an (E)-penta-2,4-dienoic acid. It is a conjugate acid of an (E,E)-piperate.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(2E,4E)-5-(1,3-benzodioxol-5-yl)penta-2,4-dienoic acid
CAS number
136-72-1 CAS number cross-checkedOther or deprecated CAS: 5285-18-7
EC numbers
226-118-4, 883-506-1
Molecular formula
C12H10O4
UNII
GFG3FLA9UR
MDL number
MFCD00047282
InChIKey
RHBGITBPARBDPH-ZPUQHVIOSA-N
InChI
InChI=1S/C12H10O4/c13-12(14)4-2-1-3-9-5-6-10-11(7-9)16-8-15-10/h1-7H,8H2,(H,13,14)/b3-1+,4-2+
Canonical SMILES
O=C(O)C=CC=Cc1ccc2c(c1)OCO2
Isomeric SMILES
C1OC2=C(O1)C=C(C=C2)/C=C/C=C/C(=O)O

Synonyms

  • (E,E)-piperic acid
  • Piperonic acid
  • Piperinic Acid
  • (2E,4E)-5-(1,3-benzodioxol-5-yl)penta-2,4-dienoic acid
  • 2,4-Pentadienoic acid, 5-(1,3-benzodioxol-5-yl)-, (E,E)-
  • 5-(1,3-Benzodioxol-5-yl)-2,4-pentadienoic acid, (2E,4E)-
  • Piperic acid (E,E)-
  • (2E,4Z)-5-(2H-1,3-benzodioxol-5-yl)penta-2,4-dienoic acid
  • Piperic acid (E,E)-form
  • 5-(3,4-Methylenedioxyphenyl)-2,4-pentadienoic acid
  • (E,E)-Piperonic Acid
  • (2E,4E)-5-(benzo[d][1,3]dioxol-5-yl)penta-2,4-dienoic acid
  • (2E,4E)-5-(2H-1,3-benzodioxol-5-yl)penta-2,4-dienoic acid
  • trans,trans-piperinic acid
  • (2E,4E)-5-(1,3-benzodioxol-5-yl)-2,4-pentadienoic acid
  • (2E,4E)-5-(1,3-dioxaindan-5-yl)penta-2,4-dienoic acid
  • Piperinsaure
  • 5-Benzo[1,3]dioxol-5-yl-penta-2,4-dienoic acid
  • Piperic acid, (E,E)-
  • 2, 5-(1,3-benzodioxol-5-yl)-
  • 5-(Benzo[d][1,3]dioxol-5-yl)penta-2,4-dienoicacid
  • (2E4E)-5-(Benzo[d][13]dioxol-5-yl)penta-24-dienoicacid
  • 5-(1,3-Benzodioxol-5-yl)-2,4-pentadienoic acid, 97%
  • (E,E)-5-(3,4-Methylenedioxyphenyl)-2,4-pentadienoic acid
  • (2E,4E)-5-(2H-benzo[3,4-d]1,3-dioxolan-5-yl)penta-2,4-dienoic acid

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
218.21 g/molcalc.
Exact mass
218.0579 Dacalc.
LogP (octanol/water)
2.07calc.
Topological polar surface area
55.76 Ųcalc.
Hydrogen bond donors
1calc.
Hydrogen bond acceptors
3calc.
Rotatable bonds
3calc.
Heavy atoms
16calc.
Rings
2calc.
Aromatic rings
1calc.
Fraction sp3 carbons
0.08calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccc2c(c1)OCO2

c1ccc2c(c1)OCO2

2 rings, 9 atoms, the 1,3-Benzodioxole ring system.

4,560 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Piperic acid suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

See the supplier
  • Specs
    Netherlands, ZoetermeerUnclaimed profile
    Piperic acidGrade, purity and minimum order on request
    Price on request
    View

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

1 supplier in 1 country

Send one request to many suppliers

Choose up to 10 suppliers or let us match your request. Compare quotes side by side, free.

Choose suppliersPost a request

Piperic acid price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

Get latest price

Uses and applications

What the substance is used for, by industry and function

Roles

  • eukaryotic metabolite
  • metabolite
  • plant metabolite

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Piperic acid is traded under.

HS 2932.99Indicative HS code

Heterocyclic compounds with oxygen hetero-atom(s) only, other

World exports in 2024
$3.81B
+10.3% vs 2023, imports $7.05B
2019 to 2024
Top exporters
  1. China28.9%
  2. Switzerland * partner reported12.7%
  3. Germany7.8%
Top importers
  1. United States49.7%
  2. China11.9%
  3. India * partner reported3.3%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Piperic acid is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Piperic acid, based on the data on this page

What is Piperic acid?

(E,E)-piperic acid is a monocarboxylic acid that is (E)-penta-2,4-dienoic acid substituted by a 1,3-benzodioxol-5-yl group at position 5. It has been isolated from black pepper (Piper nigrum). It has a role as a plant metabolite. It is a member of benzodioxoles and an alpha,beta-unsaturated monocarboxylic acid.

What is the CAS number of Piperic acid?

The CAS registry number of Piperic acid is 136-72-1. Other or deprecated CAS numbers: 5285-18-7.

What is the molecular formula and weight of Piperic acid?

The molecular formula of Piperic acid is C12H10O4 and its molar mass is 218.21 g/mol.

What is Piperic acid used for?

Known uses and roles of Piperic acid include eukaryotic metabolite, metabolite and plant metabolite.

Is Piperic acid hazardous?

No GHS hazard classification for Piperic acid is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Piperic acid?

Piperic acid is usually classified under HS code 293299 (Heterocyclic compounds with oxygen hetero-atom(s) only, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Piperic acid?

CompoundList lists 1 supplier of Piperic acid in Netherlands. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Piperic acid?

Suppliers quote Piperic acid on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Piperic acid

Get quotes for Piperic acid

Post one free request with your grade, quantity and destination. Matching suppliers send quotes you can compare side by side.
Post a request Sell Piperic acid
Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
Embed this structure on your websiteShow code

Paste this code into your page to show the 2D structure of Piperic acid with a 3D view, its CAS number where known and a link back to this page. Free to use with the link kept.

<iframe src="https://www.compoundlist.com/embed/structure/piperic-acid-136-72-1" title="Piperic acid structure on CompoundList" width="360" height="420" style="border:1px solid #E7E2DA;border-radius:12px;max-width:100%" loading="lazy" referrerpolicy="strict-origin-when-cross-origin"></iframe>
Preview the embed

Explore more in Heterocyclic compounds or HS code 293299

1 supplier
Free quotes, contact stays private
Get quotes