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Heterocyclic building blocks

Acifran

Also known as Reductol, Acifranum, AY-25,712

CAS 72420-38-3Formula C12H10O4Molar mass 218.21 g/mol
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Acifran chemical structure, C12H10O4, CAS 72420-38-3
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
72420-38-3
Formula
C12H10O4
Molar mass
218.21 g/mol
HS code
293219
Category
Heterocyclic building blocks

What is Acifran?

Plain description, key identifiers and synonyms

Acifran is an agonist of niacin receptors capable of mimicking niacin's ability to increase high-density lipoprotein (HDL). Acifran produces these effects at lower doses and without the skin flushing side-effects associated with niacin treatment.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
5-methyl-4-oxo-5-phenylfuran-2-carboxylic acid
CAS number
72420-38-3 CAS number cross-checkedOther or deprecated CAS: 77103-91-4, 77103-92-5
Molecular formula
C12H10O4
UNII
61IZ92GN57, B1X701S0MV, FP3LLW01BL
MDL number
MFCD00865746
InChIKey
DFDGRKNOFOJBAJ-UHFFFAOYSA-N
InChI
InChI=1S/C12H10O4/c1-12(8-5-3-2-4-6-8)10(13)7-9(16-12)11(14)15/h2-7H,1H3,(H,14,15)
SMILES (canonical and isomeric)
CC1(C(=O)C=C(O1)C(=O)O)C2=CC=CC=C2

Synonyms

  • Reductol
  • Acifranum
  • AY-25,712
  • 5-methyl-4-oxo-5-phenylfuran-2-carboxylic acid
  • 2-Furancarboxylic acid, 4,5-dihydro-5-methyl-4-oxo-5-phenyl-
  • 2-methyl-2-phenyl-3(2H)furanone-5-carboxylic acid
  • 4,5-dihydro-5-methy1-4-oxo-5-pheny1-2-furancarboxylic acid
  • Acifran, (+)-
  • Acifran, (-)-
  • 4,5-Dihydro-5-methyl-4-oxo-5-phenyl-2-furancarboxylic acid
  • Acifran (+)-form
  • Acifran (-)-form
  • 5-methyl-4-oxo-5-phenyl-4,5-dihydrofuran-2-carboxylic acid
  • AY 25712, Acifran
  • 2-Furancarboxylic acid, 4,5-dihydro-5-methyl-4-oxo-5-phenyl-, (+)-
  • 2-Furancarboxylic acid, 4,5-dihydro-5-methyl-4-oxo-5-phenyl-, (-)-
  • AY 25712
  • 5-Methyl-4-oxo-5-phenyl-4,5-dihydro-furan-2-carboxylic acid
  • Reductol (TN)
  • (+)-acifran
  • (-)-acifran
  • (+-)-4,5-Dihydro-5-methyl-4-oxo-5-phenyl-2-furoic acid
  • Acifran (USAN/INN)
  • (R,S)-4,5-Dihydro-5-methyl-4-oxo-5-phenyl-2-furancarbonsaeure
  • 5-methyl-4-oxo-5-phenyl-furan-2-carboxylic acid
Show all 30 synonyms
  • 4,5-Dihydro-5-methyl-4-oxo-5-phenylfuran-2-carboxylic acid
  • 2-Furancarboxylic acid, 4,5-dihydro-5-methyl-4-oxo-5-phenyl-, (+-)-
  • 5-methyl-4-oxo-5-phenyl-4,5-dihydro-2-furancarboxylic acid
  • (+/-)-4,5-Dihydro-5-methyl-4-oxo-5-phenyl-2-furoic acid
  • 2-Furancarboxylic acid, 4,5-dihydro-5-methyl-4-oxo-5-phenyl-, (+/-)-

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
218.21 g/molcalc.
Exact mass
218.0579 Dacalc.
LogP (octanol/water)
1.47calc.
Topological polar surface area
63.6 Ųcalc.
Hydrogen bond donors
1calc.
Hydrogen bond acceptors
3calc.
Rotatable bonds
2calc.
Heavy atoms
16calc.
Rings
2calc.
Aromatic rings
1calc.
Fraction sp3 carbons
0.17calc.
Formal charge
0calc.
Stereocentres
1calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C1C=COC1c1ccccc1

O=C1C=COC1c1ccccc1

2 rings, 12 atoms.

12 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Acifran suppliers

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Acifran price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Acifran is traded under.

HS 2932.19Indicative HS code

Compounds containing an unfused furan ring (whether or not hydrogenated) in the…

World exports in 2024
$2.62B
−6.4% vs 2023, imports $2.56B
2019 to 2024
Top exporters
  1. Germany57.9%
  2. Italy11.5%
  3. China10.4%
Top importers
  1. Greece40.4%
  2. Japan16.3%
  3. Germany12.8%
Reported customs values in USD, not prices.Full trade data

The HS code shown for Acifran is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Acifran, based on the data on this page

What is Acifran?

Acifran is an agonist of niacin receptors capable of mimicking niacin's ability to increase high-density lipoprotein (HDL). Acifran produces these effects at lower doses and without the skin flushing side-effects associated with niacin treatment.

What is the CAS number of Acifran?

The CAS registry number of Acifran is 72420-38-3. Other or deprecated CAS numbers: 77103-91-4, 77103-92-5.

What is the molecular formula and weight of Acifran?

The molecular formula of Acifran is C12H10O4 and its molar mass is 218.21 g/mol.

What is Acifran used for?

Known uses and roles of Acifran include building blocks in research and laboratory and screening compounds in research and laboratory.

Is Acifran hazardous?

No GHS hazard classification for Acifran is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Acifran?

Acifran is usually classified under HS code 293219 (Compounds containing an unfused furan ring (whether or not hydrogenated) in the…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Acifran?

Post a free request on CompoundList and suppliers of Acifran will send you quotes. Your contact details stay private until you accept a quote.

What is the price of Acifran?

Suppliers quote Acifran on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Acifran

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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