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Other active pharmaceutical ingredients

Pralidoxime

Also known as Pralidoximum, Pralidoxime ion, Pralidoxime cation

CAS 6735-59-7Formula C7H9N2O+Molar mass 137.16 g/molEC 229-787-0
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Pralidoxime chemical structure, C7H9N2O+, CAS 6735-59-7
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
6735-59-7
Formula
C7H9N2O+
Molar mass
137.16 g/mol
EC number
229-787-0
HS code
293339
Category
Other active pharmaceutical ingredients

What is Pralidoxime?

Plain description, key identifiers and synonyms

Pralidoxime is a pyridinium ion that is 1-methylpyridinium substituted by a (hydroxyimino)methyl group at position 2. It has a role as an antidote to sarin poisoning, a cholinergic drug, a cholinesterase reactivator and an antidote to organophosphate poisoning.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(NE)-N-[(1-methylpyridin-1-ium-2-yl)methylidene]hydroxylamine
CAS number
6735-59-7 CAS number cross-checkedOther or deprecated CAS: 25615-00-3, 45765-69-3
EC number
229-787-0
Molecular formula
C7H9N2O+
UNII
P7MU9UTP52
InChIKey
JBKPUQTUERUYQE-UHFFFAOYSA-O
InChI
InChI=1S/C7H8N2O/c1-9-5-3-2-4-7(9)6-8-10/h2-6H,1H3/p+1
Canonical SMILES
C[n+]1ccccc1C=NO
Isomeric SMILES
C[N+]1=CC=CC=C1/C=N/O

Synonyms

  • Pralidoximum
  • Pralidoxime ion
  • Pralidoxime cation
  • (1-methylpyridin-2-ylidene)methyl-oxoazanium
  • 1-methylpyridinium-2-aldoxime ion
  • 2-Pam bromide
  • pyridine-2-aldoxime methachloride
  • 2-hydroxyiminomethyl-1-methylpyridinium
  • 2-hydroxyiminomethylpyridinium methylmethanesulfonate
  • Duodote
  • (NE)-N-[(1-methylpyridin-1-ium-2-yl)methylidene]hydroxylamine
  • 2-[(E)-(hydroxyimino)methyl]-1-methylpyridinium
  • Atnaa
  • Pyridinium, 2-((hydroxyimino)methyl)-1-methyl-, iodide
  • Pralidoxime (3)
  • 1-Methyl-2-pyridinium aldoxime
  • 2-((Hydroxyimino)methyl)-1-methylpyridinium
  • 2-((hydroxyimino)methyl)-1-methylpyridin-1-ium
  • (2E)-1-methylpyridin-1-ium-2-carbaldehyde oxime
  • 2-[(E)-(Hydroxyimino)methyl]-1-methylpyridin-1-ium

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
137.16 g/molcalc.
Exact mass
137.0709 Dacalc.
LogP (octanol/water)
0.32calc.
Topological polar surface area
36.47 Ųcalc.
Hydrogen bond donors
1calc.
Hydrogen bond acceptors
2calc.
Rotatable bonds
1calc.
Heavy atoms
10calc.
Rings
1calc.
Aromatic rings
1calc.
Fraction sp3 carbons
0.14calc.
Formal charge
1calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccncc1

c1ccncc1

1 ring, 6 atoms, the Pyridine ring system.

118,162 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Pralidoxime suppliers

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All 2 suppliers

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Where suppliers are based

2 suppliers in 2 countries

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Pralidoxime price

Indicative price range per kg from live supplier offers

No published prices right now

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Uses and applications

What the substance is used for, by industry and function

Antidotes, Cholinesterase Reactivators.

Veterinary medication:.

Pharmacological actions

  • Antidotes
  • Cholinesterase Reactivators

Roles

  • antidote
  • antidote to organophosphate poisoning
  • antidote to sarin poisoning
  • cholinergic drug
  • cholinesterase reactivator
  • enzyme reactivator
  • neurotransmitter agent
  • pharmaceutical
  • protective agent

Pharmacology

Pralidoxime is a Cholinesterase Reactivator. The mechanism of action of pralidoxime is as a Cholinesterase Reactivator.

How it is made

Picolinal is converted to its oxime, which is then quaternized with dimethyl sulfate. Metathesis of the resulting pralidoxime methosulfate with HCl yields the official chloride. (Pralidoxime chloride)

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • Active ingredient in FDA approved drug labels

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Pralidoxime is traded under.

HS 2933.39Indicative HS code

Heterocyclic compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure…

World exports in 2024
$9.16B
−17.9% vs 2023, imports $10.6B
2019 to 2024
Top exporters
  1. China21.5%
  2. India * partner reported12.3%
  3. Ireland11.6%
Top importers
  1. Germany14.2%
  2. United States12.8%
  3. Brazil10.1%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Pralidoxime is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Pralidoxime, based on the data on this page

What is Pralidoxime?

Pralidoxime is a pyridinium ion that is 1-methylpyridinium substituted by a (hydroxyimino)methyl group at position 2. It has a role as an antidote to sarin poisoning, a cholinergic drug, a cholinesterase reactivator and an antidote to organophosphate poisoning.

What is the CAS number of Pralidoxime?

The CAS registry number of Pralidoxime is 6735-59-7. Other or deprecated CAS numbers: 25615-00-3, 45765-69-3.

What is the molecular formula and weight of Pralidoxime?

The molecular formula of Pralidoxime is C7H9N2O+ and its molar mass is 137.16 g/mol.

What is Pralidoxime used for?

Antidotes, Cholinesterase Reactivators. Veterinary medication:.

Is Pralidoxime hazardous?

No GHS hazard classification for Pralidoxime is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Pralidoxime?

Pralidoxime is usually classified under HS code 293339 (Compounds containing an unfused pyridine ring (whether or not hydrogenated) in the…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Pralidoxime?

CompoundList lists 2 suppliers of Pralidoxime in China and Hong Kong. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Pralidoxime?

Suppliers quote Pralidoxime on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Pralidoxime

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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