Prasugrel
Also known as 5-(2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl acetate, prasugrelum, 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl acetate
Key facts
What buyers check first
- CAS number
- 150322-43-3
- Formula
- C20H20FNO3S
- Molar mass
- 373.45 g/mol
- EC number
- 801-962-1
- HS code
- 293499
- Category
- Pharmaceuticals and APIs
What is Prasugrel?
Plain description, key identifiers and synonyms
5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl acetate is a member of the class of thienopyridines that is 2-acetoxy-4,5,6,7-tetrahydrothieno[3,2-c]pyridine in which the amino hydrogen is replaced by a 2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl group. It is a ketone, a thienopyridine, an acetate ester, a tertiary amino compound, a member of cyclopropanes and a member of monofluorobenzenes.
Prasugrel is a drug that acts as a platelet inhibitor and is used to prevent formation of blood clots.
Identifiers
Registry numbers, names and line notations, tap to copy
- IUPAC name
- [5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-6,7-dihydro-4H-thieno[3,2-c]pyridin-2-yl] acetate
- CAS number
- 150322-43-3 CAS number cross-checked
- EC number
- 801-962-1
- Molecular formula
- C20H20FNO3S
- UNII
- 34K66TBT99
- MDL number
- MFCD09954140
- InChIKey
- DTGLZDAWLRGWQN-UHFFFAOYSA-N
- InChI
- InChI=1S/C20H20FNO3S/c1-12(23)25-18-10-14-11-22(9-8-17(14)26-18)19(20(24)13-6-7-13)15-4-2-3-5-16(15)21/h2-5,10,13,19H,6-9,11H2,1H3
- SMILES (canonical and isomeric)
- CC(=O)OC1=CC2=C(S1)CCN(C2)C(C3=CC=CC=C3F)C(=O)C4CC4
Synonyms
- 5-(2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl acetate
- prasugrelum
- 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl acetate
- Ethanone, 2-[2-(acetyloxy)-6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl]-1-cyclopropyl-2-(2-fluorophenyl)-
- 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4H,5H,6H,7H-thieno[3,2-c]pyridin-2-yl acetate
- Ethanone, 2-(2-(acetyloxy)-6,7-dihydrothieno(3,2-c)pyridin-5(4H)-yl)-1-cyclopropyl-2-(2-fluorophenyl)-
- 5-(2-Cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl)-4,5,6,7-tetrahydrothieno(3,2-c)pyridin-2-yl acetate
- (5-(2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl)-6,7-dihydro-4H-thieno(4,5-c)pyridin-2-yl) acetate
- [5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-6,7-dihydro-4H-thieno[4,5-c]pyridin-2-yl] acetate
- 5-(2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl)-4H,5H,6H,7H-thieno(3,2-c)pyridin-2-yl acetate
- 2-[2-(Acetyloxy)-6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl]-1-cyclopropyl-2-(2-fluorophenyl)ethanone
- [5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-6,7-dihydro-4H-thieno[3,2-c]pyridin-2-yl] acetate
- Pcr 4099
- Prasugrel (Effient)
- Prasugrel?
- Prasugrel-[d5]
- 2-(2-(Acetyloxy)-6,7-dihydrothieno(3,2-c)pyridin-5(4H)-yl)-1-cyclopropyl-2-(2-fluorophenyl)ethanone
- Prasugrel (Standard)
- Prasugrel - Bio-X trade mark
- Prasugrel, >=98% (HPLC)
- [5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxo-ethyl]-6,7-dihydro-4H-thieno[3,2-c]pyridin-2-yl] acetate
- 2-acetoxy-5-(alpha-cyclopropylcarbonyl-2-fluorobenzyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridine
- Ethanone, 2-(2-(acetyloxy)-6,7-dihydr
- 2-Acetoxy-5-(alpha-cyclopropylcarbonyl-2-fluorobenzyl)-4,5,6,7-tetrahydrothieno-(3,2-c)pyridine
- 2-Acetoxy-5-(alpha-cyclopropylcarbonyl-2-fluorobenzyl)-4,5,6,7-tetrahydrothieno[3,2-c] pyridine
Show all 28 synonymsShow fewer synonyms
- 2-Acetoxy-5-(alpha-cyclopropylcarbonyl-2-fluorobenzyl)4,5,6,7-tetrahydrothieno[3,2-c]pyridine
- 2-acetyloxy-5-(alpha-cyclopropylcarbonyl-2-fluorobenzyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridine
- 2-acetyloxy-5-(alpha-cycloproylcarbonyl-2-fluorobenzyl)-4,5,6,7-tetrahydrothieno[3,2-C]pyridine
Physical and chemical properties
Measured values and descriptors computed from the structure
Physical and chemical properties
Measured values, check the supplier specification for your grade
No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.
Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.
Computed descriptors
Calculated from the structure, useful for screening and formulation
| Molecular weight | 373.45 g/molcalc.Computed value |
|---|---|
| Exact mass | 373.1148 Dacalc.Computed value |
| LogP (octanol/water) | 3.89calc.Computed value |
| Topological polar surface area | 46.61 ร
ยฒcalc.Computed value |
| Hydrogen bond donors | 0calc.Computed value |
| Hydrogen bond acceptors | 5calc.Computed value |
| Rotatable bonds | 5calc.Computed value |
| Heavy atoms | 26calc.Computed value |
| Rings | 4calc.Computed value |
| Aromatic rings | 2calc.Computed value |
| Fraction sp3 carbons | 0.4calc.Computed value |
| Formal charge | 0calc.Computed value |
| Stereocentres | 1calc.Computed value |
| Lipinski rule of five | Passes (0 violations)calc.Computed value |
Calculated for screening. Confirm critical figures with the supplier.
Murcko scaffold
The ring system that remains when every side chain is removed
Safety and hazards
GHS classification summary, not a safety data sheet
Hazard statements
- H302Harmful if swallowed.
- H370Causes damage to organs.
- H373May cause damage to organs through prolonged or repeated exposure.
- H411Toxic to aquatic life with long lasting effects.
Precautionary statements (12)
- P260Do not breathe dust, fume, gas, mist, vapours or spray.
- P264Wash skin thoroughly after handling.
- P270Do not eat, drink or smoke when using this product.
- P273Avoid release to the environment.
- P301 + P317If swallowed: Get medical help.
- P308 + P316If exposed or concerned: Get emergency medical help immediately.
- P319Get medical help if you feel unwell.
- P321Specific treatment (see supplemental first aid instructions on the label).
- P330Rinse mouth.
- P391Collect spillage.
- P405Store locked up.
- P501Dispose of contents and container in accordance with local regulations.
GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.
Full safety data and first aidPrasugrel suppliers
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- ChinaUnclaimed profilePrasugrelGrade, purity and minimum order on requestPrice on request
- China, Hangzhou ManufacturerUnclaimed profilePrasugrelGrade, purity and minimum order on requestPrice on request
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Where suppliers are based
102 suppliers in 14 countries
- China39
- United States36
- Germany5
- United Kingdom4
- Spain3
- Canada2
- and 8 more countries
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Prasugrel price
Indicative price range per kg from live supplier offers
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Uses and applications
What the substance is used for, by industry and function
Pharmacology
Prasugrel is a P2Y12 Platelet Inhibitor. The mechanism of action of prasugrel is as a P2Y12 Receptor Antagonist. The physiologic effect of prasugrel is by means of Decreased Platelet Aggregation.
Regulatory status
Inventories, regulations and trade controls that list this substance
Health and food
- Active ingredient in FDA approved drug labels
HS code and trade data
Customs classification and reported world trade statistics
Global trade
World import and export statistics for the HS code Prasugrel is traded under.
Nucleic acids and their salts, other heterocyclic compounds, not elsewhere classified in heading 2934
- United States24.5%
- Germany23.1%
- Japan4.5%
The HS code shown for Prasugrel is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.
Frequently asked questions
Quick answers about Prasugrel, based on the data on this page
What is Prasugrel?
What is the CAS number of Prasugrel?
What is the molecular formula and weight of Prasugrel?
Is Prasugrel hazardous?
What is the HS code of Prasugrel?
Where can I buy Prasugrel?
What is the price of Prasugrel?
Guides for buyers
Practical guides that help when you source, ship or handle Prasugrel
- Article, QualityPharma grades explained: IP vs BP vs USP vs EPWhat the Indian, British, US and European pharmacopoeias are, how their monographs differ, what multi grade claims mean and why a grade alone does not make a product fit for medicines.Read
- Guide, SafetyHow to read a safety data sheet in 10 minutesA section by section method to pull the essentials out of any 16 section SDS: identity, hazards, composition, storage, PPE, properties, transport and emergency measures.Read
- Guide, SafetyGHS pictograms, signal words and hazard statements explainedA practical guide to the nine GHS pictograms, the signal words Danger and Warning, H and P statements, and how to read a chemical label in seconds.Read
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