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Heterocyclic building blocks

Profadol

Also known as Profadolum, Dl-profadol, m-(1-Methyl-3-propyl-3-pyrrolidinyl)phenol

CAS 428-37-5Formula C14H21NOMolar mass 219.33 g/mol
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Profadol chemical structure, C14H21NO, CAS 428-37-5
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
428-37-5
Formula
C14H21NO
Molar mass
219.33 g/mol
HS code
293399
Category
Heterocyclic building blocks

What is Profadol?

Plain description, key identifiers and synonyms

Profadol is a chemical substance with the molecular formula C14H21NO and a molar mass of 219.33 g/mol. Its CAS registry number is 428-37-5. The IUPAC name is 3-(1-methyl-3-propylpyrrolidin-3-yl)phenol.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
3-(1-methyl-3-propylpyrrolidin-3-yl)phenol
CAS number
428-37-5 CAS number cross-checkedOther or deprecated CAS: 13104-68-2, 13104-69-3
Molecular formula
C14H21NO
UNII
41GDG43FTT, 89XH4S010S, 9TM4MXU27E
InChIKey
VFUGCQKESINERB-UHFFFAOYSA-N
InChI
InChI=1S/C14H21NO/c1-3-7-14(8-9-15(2)11-14)12-5-4-6-13(16)10-12/h4-6,10,16H,3,7-9,11H2,1-2H3
SMILES (canonical and isomeric)
CCCC1(CCN(C1)C)C2=CC(=CC=C2)O

Synonyms

  • Profadolum
  • Dl-profadol
  • m-(1-Methyl-3-propyl-3-pyrrolidinyl)phenol
  • Phenol, m-(1-methyl-3-propyl-3-pyrrolidinyl)-
  • CI-572 FREE BASE
  • A-2205 FREE BASE
  • Profadol, (+)-
  • Profadol, (-)-
  • 3-(m-Hydroxyphenyl)-1-methyl-3-propylpyrrolidine
  • Pyrrolidine, 3-(m-hydroxyphenyl)-1-methyl-3-propyl-
  • CI 572
  • Phenol, 3-(1-methyl-3-propyl-3-pyrrolidinyl)-, (+)-
  • Phenol, m-(1-methyl-3-propyl-3-pyrrolidinyl)-, (+)-
  • Phenol, 3-(1-methyl-3-propyl-3-pyrrolidinyl)-, (-)-
  • Phenol, m-(1-methyl-3-propyl-3-pyrrolidinyl)-, (-)-
  • dl-Profadol, m-(1-Methyl-3-propyl-3-pyrrolidinyl)phenol
  • 3-(1-methyl-3-propylpyrrolidin-3-yl)phenol
  • 3-(1-Methyl-3-propyl-3-pyrrolidinyl)phenol #
  • m-(1-Methyl-3-propyl-pyrrolidin-3-yl)-phenol
  • Phenol, 3-(1-methyl-3-propyl-3-pyrrolidinyl)-

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
219.33 g/molcalc.
Exact mass
219.1623 Dacalc.
LogP (octanol/water)
2.77calc.
Topological polar surface area
23.47 Ųcalc.
Hydrogen bond donors
1calc.
Hydrogen bond acceptors
2calc.
Rotatable bonds
3calc.
Heavy atoms
16calc.
Rings
2calc.
Aromatic rings
1calc.
Fraction sp3 carbons
0.57calc.
Formal charge
0calc.
Stereocentres
1calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccc(C2CCNC2)cc1

c1ccc(C2CCNC2)cc1

2 rings, 11 atoms, the 3-Phenylpyrrolidine ring system.

4,372 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Profadol suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

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Profadol price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Profadol is traded under.

HS 2933.99Indicative HS code

Heterocyclic compounds with nitrogen hetero-atom(s) only, other

World exports in 2024
$12.1B
−31.0% vs 2023, imports $28.8B
2019 to 2024
Top exporters
  1. China30.5%
  2. India * partner reported16.3%
  3. Ireland9.0%
Top importers
  1. Slovenia31.7%
  2. Italy24.2%
  3. United States5.0%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Profadol is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Profadol, based on the data on this page

What is Profadol?

Profadol is a chemical substance with the molecular formula C14H21NO and a molar mass of 219.33 g/mol. Its CAS registry number is 428-37-5. The IUPAC name is 3-(1-methyl-3-propylpyrrolidin-3-yl)phenol.

What is the CAS number of Profadol?

The CAS registry number of Profadol is 428-37-5. Other or deprecated CAS numbers: 13104-68-2, 13104-69-3.

What is the molecular formula and weight of Profadol?

The molecular formula of Profadol is C14H21NO and its molar mass is 219.33 g/mol.

What is Profadol used for?

Known uses and roles of Profadol include building blocks in research and laboratory and screening compounds in research and laboratory.

Is Profadol hazardous?

No GHS hazard classification for Profadol is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Profadol?

Profadol is usually classified under HS code 293399 (Heterocyclic compounds with nitrogen hetero-atom(s) only, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Profadol?

Post a free request on CompoundList and suppliers of Profadol will send you quotes. Your contact details stay private until you accept a quote.

What is the price of Profadol?

Suppliers quote Profadol on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Profadol

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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