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Steroids and sterols

Promegestone

Also known as Surgestone, Promegestona, Promegestonum

CAS 34184-77-5Formula C22H30O2Molar mass 326.48 g/molEC 682-405-8
GHS signal word: Danger. Pictograms: Serious health hazard 3 suppliers listed
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Promegestone chemical structure, C22H30O2, CAS 34184-77-5
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
34184-77-5
Formula
C22H30O2
Molar mass
326.48 g/mol
EC number
682-405-8
HS code
293723
Category
Steroids and sterols

What is Promegestone?

Plain description, key identifiers and synonyms

Promegestone is a progestin consisting of 17beta-propionylestra-4,9-dien-3-one substituted at position 17 by a methyl group. It has a role as an antineoplastic agent, a progestin and a progesterone receptor agonist. It is a 20-oxo steroid and a 3-oxo-Delta(4) steroid. It derives from a hydride of an estrane.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(8S,13S,14S,17S)-13,17-dimethyl-17-propanoyl-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-3-one
CAS number
34184-77-5 CAS number cross-checked
EC number
682-405-8
Molecular formula
C22H30O2
UNII
9XE0V2SQYX
InChIKey
QFFCYTLOTYIJMR-XMGTWHOFSA-N
InChI
InChI=1S/C22H30O2/c1-4-20(24)22(3)12-10-19-18-7-5-14-13-15(23)6-8-16(14)17(18)9-11-21(19,22)2/h13,18-19H,4-12H2,1-3H3/t18-,19+,21+,22-/m1/s1
Canonical SMILES
CCC(=O)C1(C)CCC2C3CCC4=CC(=O)CCC4=C3CCC21C
Isomeric SMILES
CCC(=O)[C@]1(CC[C@@H]2[C@@]1(CCC3=C4CCC(=O)C=C4CC[C@@H]23)C)C

Synonyms

  • Surgestone
  • Promegestona
  • Promegestonum
  • (8S,13S,14S,17S)-13,17-dimethyl-17-propanoyl-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-3-one
  • (17beta)-17-methyl-17-propionylestra-4,9-dien-3-one
  • Promestone
  • Estra-4,9-dien-3-one, 17-methyl-17-(1-oxopropyl)-, (17beta)-
  • (8S,13S,14S,17S)-13,17-dimethyl-17-propanoyl-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta(a)phenanthren-3-one
  • 17,21-Dimethyl-19-nor-4,9-pregnadiene-3,20-dione
  • RU 5020
  • Promegestone (INN)
  • [3H]R5020
  • (8S,13S,14S,17S)-13,17-dimethyl-17-propionyl-1,2,6,7,8,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one
  • 17alpha-methyl-17-propionylestra-4,9-dien-3-one
  • 17,21-dimethyl-19-norpregna-4,9(10)-diene-3,20-dione
  • Surgestone (TN)
  • 17alpha-Methyl-1,7-propionylestra-4,9-dien-3-one
  • Estra-4,9-dien-3-one, 17-alpha-methyl-17-propionyl-
  • Estra-4,9-dien-3-one, 17-methyl-17-(1-oxopropyl)-, (17-beta)-
  • Estra-4,9-dien-3-one, 17-methyl-17-(1-oxopropyl)-, (17|A)-
  • (10S,11S,14S,15S)-14,15-dimethyl-14-propanoyltetracyclo[8.7.0.0, {2,7}.0, {11,15}]heptadeca-1,6-dien-5-one
  • (1S,3aS,3bS,11aS)-1,11a-Dimethyl-1-propanoyl-1,2,3,3a,3b,4,5,8,9,10,11,11a-dodecahydro-7H-cyclopenta[a]phenanthren-7-one

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
326.48 g/molcalc.
Exact mass
326.2246 Dacalc.
LogP (octanol/water)
5.18calc.
Topological polar surface area
34.14 Ųcalc.
Hydrogen bond donors
0calc.
Hydrogen bond acceptors
2calc.
Rotatable bonds
2calc.
Heavy atoms
24calc.
Rings
4calc.
Aromatic rings
0calc.
Fraction sp3 carbons
0.73calc.
Formal charge
0calc.
Stereocentres
4calc.
Lipinski rule of five
Passes (1 violation)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C1C=C2CCC3C(=C2CC1)CCC1CCCC13

O=C1C=C2CCC3C(=C2CC1)CCC1CCCC13

4 rings, 18 atoms.

30 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS08: Serious health hazard
Serious health hazard

Hazard statements

  • H340May cause genetic defects.
Precautionary statements (5)
  • P203Obtain, read and follow all safety instructions before use.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P318If exposed or concerned, get medical advice.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Promegestone suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 3 suppliers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

3 suppliers in 2 countries

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Promegestone price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

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Uses and applications

What the substance is used for, by industry and function

Roles

  • agonist
  • antineoplastic agent
  • hormone
  • hormone agonist
  • hormone receptor modulator
  • molecular messenger
  • pharmaceutical
  • progesterone receptor agonist
  • progestin
  • progestogen
  • receptor modulator
  • sex hormone

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Promegestone is traded under.

HS 2937.23Indicative HS code

Oestrogens and progestogens

World exports in 2024
$762M
−2.3% vs 2023, imports $693M
2019 to 2024
Top exporters
  1. China42.9%
  2. Italy18.4%
  3. Netherlands8.9%
Top importers
  1. India * partner reported12.1%
  2. United States11.0%
  3. Belgium8.3%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Promegestone is indicative (it is known at chapter level only). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Promegestone, based on the data on this page

What is Promegestone?

Promegestone is a progestin consisting of 17beta-propionylestra-4,9-dien-3-one substituted at position 17 by a methyl group. It has a role as an antineoplastic agent, a progestin and a progesterone receptor agonist. It is a 20-oxo steroid and a 3-oxo-Delta(4) steroid. It derives from a hydride of an estrane.

What is the CAS number of Promegestone?

The CAS registry number of Promegestone is 34184-77-5.

What is the molecular formula and weight of Promegestone?

The molecular formula of Promegestone is C22H30O2 and its molar mass is 326.48 g/mol.

What is Promegestone used for?

Known uses and roles of Promegestone include agonist, antineoplastic agent, hormone, hormone agonist, hormone receptor modulator and 7 more.

Is Promegestone hazardous?

Promegestone carries the GHS signal word "Danger". Main hazards: may cause genetic defects. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Promegestone?

Promegestone is usually classified under HS code 293723 (Oestrogens and progestogens). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Promegestone?

CompoundList lists 3 suppliers of Promegestone in China and Hong Kong. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Promegestone?

Suppliers quote Promegestone on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Promegestone

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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