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Central nervous system drugs

Proparacaine

Also known as Proxymetacaine, 2-(Diethylamino)ethyl 3-amino-4-propoxybenzoate, Proximetacainum

CAS 499-67-2Formula C16H26N2O3Molar mass 294.40 g/molEC 207-884-9
9 suppliers listed Drug substance
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Proparacaine chemical structure, C16H26N2O3, CAS 499-67-2
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
499-67-2
Formula
C16H26N2O3
Molar mass
294.40 g/mol
EC number
207-884-9
HS code
292250
Category
Central nervous system drugs

What is Proparacaine?

Plain description, key identifiers and synonyms

Proparacaine is a benzoate ester.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
2-(diethylamino)ethyl 3-amino-4-propoxybenzoate
CAS number
499-67-2 CAS number cross-checked
EC number
207-884-9
Molecular formula
C16H26N2O3
UNII
B4OB0JHI1X
MDL number
MFCD00864455
InChIKey
KCLANYCVBBTKTO-UHFFFAOYSA-N
InChI
InChI=1S/C16H26N2O3/c1-4-10-20-15-8-7-13(12-14(15)17)16(19)21-11-9-18(5-2)6-3/h7-8,12H,4-6,9-11,17H2,1-3H3
SMILES (canonical and isomeric)
CCCOC1=C(C=C(C=C1)C(=O)OCCN(CC)CC)N

Synonyms

  • Proxymetacaine
  • 2-(Diethylamino)ethyl 3-amino-4-propoxybenzoate
  • Proximetacainum
  • Proximetacaina
  • Prossimetacaina
  • Proxymetacainum
  • 3-Amino-4-propoxybenzoic acid 2-(diethylamino)ethyl ester
  • Benzoic acid, 3-amino-4-propoxy-, 2-(diethylamino)ethyl ester
  • proxymethacaine
  • Proxymetacaine (INN)
  • 2-(Diethylamino)ethyl 3-amino-4-propoxy-benzoate
  • beta-(Diethylamino)ethyl 4-n-propoxybenzoate
  • 3-amino-4-propoxy-,2-(diethylamino)ethyl ester Benzoic acid
  • 3-Amino-4-propoxy-benzoic acid 2-diethylamino-ethyl ester, hydrochloride

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
294.40 g/molcalc.
Exact mass
294.1943 Dacalc.
LogP (octanol/water)
2.56calc.
Topological polar surface area
64.79 Ųcalc.
Hydrogen bond donors
1calc.
Hydrogen bond acceptors
5calc.
Rotatable bonds
9calc.
Heavy atoms
21calc.
Rings
1calc.
Aromatic rings
1calc.
Fraction sp3 carbons
0.56calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccccc1

c1ccccc1

1 ring, 6 atoms, the Benzene ring system.

485,677 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Proparacaine suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 9 suppliers
9 of 9 offers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

9 suppliers in 5 countries

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Proparacaine price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

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Uses and applications

What the substance is used for, by industry and function

Use classes: Pharmaceuticals.

Industries and functions

Pharmacological actions

  • Anesthetics, Local

Roles

  • analgesic
  • pharmaceutical

Pharmacology

Proparacaine is a Local Anesthetic. The physiologic effect of proparacaine is by means of Local Anesthesia.

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • Active ingredient in FDA approved drug labels

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Proparacaine is traded under.

HS 2922.50Indicative HS code

Amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function

World exports in 2024
$3.29B
−5.9% vs 2023, imports $3.19B
2019 to 2024
Top exporters
  1. China39.2%
  2. United Kingdom27.1%
  3. India * partner reported4.8%
Top importers
  1. United States20.7%
  2. Germany7.6%
  3. Italy6.6%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Proparacaine is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Proparacaine, based on the data on this page

What is Proparacaine?

Proparacaine is a benzoate ester.

What is the CAS number of Proparacaine?

The CAS registry number of Proparacaine is 499-67-2.

What is the molecular formula and weight of Proparacaine?

The molecular formula of Proparacaine is C16H26N2O3 and its molar mass is 294.40 g/mol.

What is Proparacaine used for?

Use classes: Pharmaceuticals.

Is Proparacaine hazardous?

No GHS hazard classification for Proparacaine is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Proparacaine?

Proparacaine is usually classified under HS code 292250 (Amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Proparacaine?

CompoundList lists 9 suppliers of Proparacaine in China, Hong Kong, India, Singapore and 1 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Proparacaine in India?

1 supplier in India list Proparacaine on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Proparacaine?

Suppliers quote Proparacaine on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Proparacaine

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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