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Screening compounds

Propiomazine hydrochloride

Also known as Largon, Propiomazine HCl, 1-(10-(2-(Dimethylamino)propyl)phenothiazin-2-yl)-1-propanone monohydrochloride

CAS 1240-15-9Formula C20H25ClN2OSMolar mass 376.95 g/mol
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Propiomazine hydrochloride chemical structure, C20H25ClN2OS, CAS 1240-15-9
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
1240-15-9
Formula
C20H25ClN2OS
Molar mass
376.95 g/mol
HS code
293430
Category
Screening compounds

What is Propiomazine hydrochloride?

Plain description, key identifiers and synonyms

Propiomazine Hydrochloride is the hydrochloride salt form of propiomazine, a phenothiazine derivative and atypical antipsychotic agent with sedative, antiemetic and antipsychotic activities. Propiomazine binds to a variety of receptors, including alpha1, dopamine, histamine H1, muscarinic, and serotonin type 2 (5-HT2) receptors. Propiomazine exerts its antiemetic and sedative effects through antagonism at histamine H1 receptors, Its antipsychotic effect is attributed to antagonistic activities at dopamine and 5-HT2 receptors.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
1-[10-[2-(dimethylamino)propyl]phenothiazin-2-yl]propan-1-one, hydrochloride
CAS number
1240-15-9 CAS number cross-checked
Molecular formula
C20H25ClN2OS
UNII
70BO17YR03
InChIKey
UGVNGSMLNPWNNA-UHFFFAOYSA-N
InChI
InChI=1S/C20H24N2OS.ClH/c1-5-18(23)15-10-11-20-17(12-15)22(13-14(2)21(3)4)16-8-6-7-9-19(16)24-20;/h6-12,14H,5,13H2,1-4H3;1H
SMILES (canonical and isomeric)
CCC(=O)C1=CC2=C(C=C1)SC3=CC=CC=C3N2CC(C)N(C)C.Cl

Synonyms

  • Largon
  • Propiomazine HCl
  • 1-(10-(2-(Dimethylamino)propyl)phenothiazin-2-yl)-1-propanone monohydrochloride
  • 1-[10-[2-(dimethylamino)propyl]phenothiazin-2-yl]propan-1-one, hydrochloride
  • 1-(10-(2-(dimethylamino)propyl)phenothiazin-2-yl)propan-1-one, hydrochloride
  • 1-[10-[2-(Dimethylamino)propyl]phenothiazin-2-yl]-1-propanone monohydrochloride
  • Propionylpromazine hydrochloride vetran&
  • 1-Propanone, 1-(10-(2-(dimethylamino)propyl)-10H-phenothiazin-2-yl)-, monohydrochloride
  • Propiomazinhydrochlorid
  • Propiomazine hydrochloride, >98%
  • (+/-)-Propiomazine hydrochloride
  • Propiomazine hydrochloride, (+/-)-
  • 1-{10-[2-(Dimethylamino)propyl]-10H-phenothiazin-2-yl}propan-1-one--hydrogen chloride (1/1)
  • 1-Propanone, 1-(10-(2-(dimethylamino)propyl)-10H-phenothiazin-2-yl)-, hydrochloride (1:1)

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
376.95 g/molcalc.
Exact mass
376.1376 Dacalc.
LogP (octanol/water)
5.25calc.
Topological polar surface area
23.55 Ųcalc.
Hydrogen bond donors
0calc.
Hydrogen bond acceptors
4calc.
Rotatable bonds
5calc.
Heavy atoms
25calc.
Rings
3calc.
Aromatic rings
2calc.
Fraction sp3 carbons
0.35calc.
Formal charge
0calc.
Stereocentres
1calc.
Components
2calc.
Lipinski rule of five
Passes (1 violation)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccc2c(c1)Nc1ccccc1S2

c1ccc2c(c1)Nc1ccccc1S2

3 rings, 14 atoms, the Phenothiazine ring system.

1,001 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Propiomazine hydrochloride suppliers

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Propiomazine hydrochloride price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Propiomazine hydrochloride is traded under.

HS 2934.30Indicative HS code

Compounds containing in the structure a phenothiazine ring-system (whether or not…

World exports in 2024
$89.3M
−7.1% vs 2023, imports $97M
2019 to 2024
Top exporters
  1. Germany21.6%
  2. France * partner reported14.6%
  3. China13.0%
Top importers
  1. United States14.2%
  2. Brazil12.7%
  3. India * partner reported10.6%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Propiomazine hydrochloride is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Propiomazine hydrochloride, based on the data on this page

What is Propiomazine hydrochloride?

Propiomazine Hydrochloride is the hydrochloride salt form of propiomazine, a phenothiazine derivative and atypical antipsychotic agent with sedative, antiemetic and antipsychotic activities.

What is the CAS number of Propiomazine hydrochloride?

The CAS registry number of Propiomazine hydrochloride is 1240-15-9.

What is the molecular formula and weight of Propiomazine hydrochloride?

The molecular formula of Propiomazine hydrochloride is C20H25ClN2OS and its molar mass is 376.95 g/mol.

What is Propiomazine hydrochloride used for?

Known uses and roles of Propiomazine hydrochloride include building blocks in research and laboratory and screening compounds in research and laboratory.

Is Propiomazine hydrochloride hazardous?

No GHS hazard classification for Propiomazine hydrochloride is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Propiomazine hydrochloride?

Propiomazine hydrochloride is usually classified under HS code 293430 (Compounds containing in the structure a phenothiazine ring-system (whether or not…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Propiomazine hydrochloride?

Post a free request on CompoundList and suppliers of Propiomazine hydrochloride will send you quotes. Your contact details stay private until you accept a quote.

What is the price of Propiomazine hydrochloride?

Suppliers quote Propiomazine hydrochloride on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Propiomazine hydrochloride

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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