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(+)-Pulegone chemical structure, C10H16O, CAS 89-82-7
2D chemical structure

Key facts

What buyers check first

Appearance
Oil
Boiling point
224 °C
Density
0.9323 at 20 °C
Solubility
Practically insoluble in water
HS code
291429
Category
Synthetic aroma chemicals
Illustrative photo, 25 litre white jerry cans of liquid in a warehouse
Typical packagingIllustrative packaging image, not the actual product

What is (+)-Pulegone?

Plain description, key identifiers and synonyms

(+)-pulegone is the (5R)-enantiomer of p-menth-4(8)-en-3-one.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(5R)-5-methyl-2-propan-2-ylidenecyclohexan-1-one
CAS number
89-82-7
EC number
201-943-2
Molecular formula
C10H16O
UNII
4LF2673R3G
MDL number
MFCD00063000
INCI name
D-PULEGONE
InChIKey
NZGWDASTMWDZIW-MRVPVSSYSA-N
InChI
InChI=1S/C10H16O/c1-7(2)9-5-4-8(3)6-10(9)11/h8H,4-6H2,1-3H3/t8-/m1/s1
Canonical SMILES
CC(C)=C1CCC(C)CC1=O
Isomeric SMILES
C[C@@H]1CCC(=C(C)C)C(=O)C1

Synonyms

  • Pulegone
  • d-Pulegone
  • Pulegon
  • (+)-(R)-Pulegone
  • (1R)-(+)-p-Menth-4(8)-en-3-one
  • Pulegone, d-
  • 3-Methyl-6-isopropylidenecyclohexanone
  • p-MENTH-4(8)-EN-3-ONE, (R)-(+)-
  • 4(8)-p-Menthen-3-one, delta-
  • 5-Methyl-2-(1-methylethylidene)cyclohexanone, (R)-
  • (5R)-5-methyl-2-propan-2-ylidenecyclohexan-1-one
  • (R)-Pulegone
  • (R)-(+)-Pulegone
  • R-(+)-Pulegone
  • Cyclohexanone, 5-methyl-2-(1-methylethylidene)-, (5R)-
  • (5R)-5-methyl-2-(propan-2-ylidene)cyclohexan-1-one
  • Cyclohexanone, 5-methyl-2-(1-methylethylidene)-, (R)-
  • (R)-5-methyl-2-(propan-2-ylidene)cyclohexanone
  • (5R)-5-Methyl-2-(1-methylethylidene)cyclohexanone
  • (R)-2-Isopropylidene-5-methylcyclohexanone
  • (R)-p-Menth-4(8)-en-3-one
  • (5R)-2-isopropylidene-5-methylcyclohexanone
  • (R)-(+)-P-MENTH-4(8)-EN-3-ONE
  • 1beta-p-menth-4(8)-en-3-one
  • (+)-4(8)-Para-menthen-3-one
Show all 35 synonyms
  • (5R)-2-isopropylidene-5-methyl-cyclohexanone
  • (+)-1-Methyl-4-isopropylidene-3-cyclohexanone
  • Pulegone (natural)
  • Pulegone, (d)
  • (R)-(+)-Pulegone 1000 microg/mL in Hexane
  • (5R)-5-methyl-2-(propan-2-ylidene)cyclohexanone
  • Pulegone (Standard)
  • Pulegone, >/=90%
  • (1R)-Pulegone
  • (R)-Pulegone - 90%

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
Oilexp.
Odour
Pleasant odor, midway between peppermint and camphorexp.
Boiling point
224 °Cexp.
Density
0.9323 at 20 °Cexp.
Solubility
Practically insoluble in waterexp.
Vapour pressure
0.123 mm Hg at 25 °C (extrapolated)exp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
152.24 g/molcalc.
Exact mass
152.1201 Dacalc.
LogP (octanol/water)
2.71calc.
Topological polar surface area
17.07 Ųcalc.
Hydrogen bond donors
0calc.
Hydrogen bond acceptors
1calc.
Rotatable bonds
0calc.
Heavy atoms
11calc.
Rings
1calc.
Aromatic rings
0calc.
Fraction sp3 carbons
0.7calc.
Formal charge
0calc.
Stereocentres
1calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, C=C1CCCCC1=O

C=C1CCCCC1=O

1 ring, 8 atoms, the Cyclohexanone, methylene- ring system.

158 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant

Hazard statements

  • H302Harmful if swallowed.
Precautionary statements (5)
  • P264Wash skin thoroughly after handling.
  • P270Do not eat, drink or smoke when using this product.
  • P301 + P317If swallowed: Get medical help.
  • P330Rinse mouth.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

(+)-Pulegone suppliers

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(+)-Pulegone price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Chemical intermediate, flavoring.

Several essential oils containing pulegone [e.g., mint oil (<2% pulegone), peppermint oil (<4% pulegone), pennyroyal oil (60%-90% pulegone)] are used for flavoring foods, drinks, and dental products.

Pennyroyal oil (60-90% pulegone) has also been used as a fragrance agent and as an herbal medicine proposed to induce menstruation and abortion.

Traditional medicine.

Cosmetic ingredient, INCI name D-PULEGONE(perfuming)

Functional uses

  • Flavouring and nutrient
  • Fragrance

Cosmetic functions

  • Perfuming

How it is made

Pulegone can be produced synthetically.

Essential oils containing pulegone are derived from many plant species, including Hedeoma pulegioides (American pennyroyal), species of the genus Bystropogon (evergreen shrubs), and species of the genus Mentha [e.g., European pennyroyal (M. pulegium), cornmint, Biblical mint]. Essential (i.e., volatile) plant oils are produced in the plant tissues by the reaction of certain constituents when tissues contact water, most oils are obtained from plants by steam distillation.

Pulegone can also be produced by shoot cultures of Mentha piperita grown in fermenters.

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • EU cosmetic ingredient inventory

United States

  • TSCA inventory (USA)
    Status: Active in US commerce

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code (+)-Pulegone is traded under.

HS 2914.29Indicative HS code

Cyclanic, cyclenic or cycloterpenic ketones without other oxygen function, other

World exports in 2024
$1B
+6.6% vs 2023, imports $980M
2019 to 2024
Top exporters
  1. China32.5%
  2. India * partner reported12.9%
  3. Germany12.3%
Top importers
  1. United States15.7%
  2. Japan8.7%
  3. Germany8.7%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for (+)-Pulegone is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about (+)-Pulegone, based on the data on this page

What is (+)-Pulegone?

(+)-pulegone is the (5R)-enantiomer of p-menth-4(8)-en-3-one.

What is the CAS number of (+)-Pulegone?

The CAS registry number of (+)-Pulegone is 89-82-7.

What is the molecular formula and weight of (+)-Pulegone?

The molecular formula of (+)-Pulegone is C10H16O and its molar mass is 152.24 g/mol.

What is (+)-Pulegone used for?

Chemical intermediate, flavoring. Several essential oils containing pulegone [e.g., mint oil (<2% pulegone), peppermint oil (<4% pulegone), pennyroyal oil (60%-90% pulegone)] are used for flavoring foods, drinks, and dental products.

Is (+)-Pulegone hazardous?

(+)-Pulegone carries the GHS signal word "Warning". Main hazards: harmful if swallowed. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of (+)-Pulegone?

(+)-Pulegone is usually classified under HS code 291429 (Cyclanic, cyclenic or cycloterpenic ketones without other oxygen function, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy (+)-Pulegone?

CompoundList lists 19 suppliers of (+)-Pulegone in China, United States, India, Germany and 1 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy (+)-Pulegone in India?

4 suppliers in India list (+)-Pulegone on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of (+)-Pulegone?

Suppliers quote (+)-Pulegone on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle (+)-Pulegone

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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