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Amines and amides

Putrescine

Also known as 1,4-diaminobutane, 1,4-butanediamine, butane-1,4-diamine

CAS 110-60-1Formula C4H12N2Molar mass 88.15 g/molEC 203-782-3
GHS signal word: Danger. Pictograms: Flammable, Corrosive, Acute toxicity (severe), Harmful or irritant 66 suppliers listed
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Putrescine chemical structure, C4H12N2, CAS 110-60-1
2D chemical structure

Key facts

What buyers check first

All properties
Appearance
Colorless oil
Melting point
27.5 °C
Boiling point
158.5 °C
Density
0.877 g/cm³ at 25 °C
Solubility
Soluble in water with strongly basic reaction
HS code
292129
Category
Amines and amides
Illustrative photo, an amber glass solvent bottle with clear liquid on a laboratory bench
Typical packagingIllustrative packaging image, not the actual product

What is Putrescine?

Plain description, key identifiers and synonyms

Putrescine is a four-carbon alkane-alpha,-diamine. It is obtained by the breakdown of amino acids and is responsible for the foul odour of putrefying flesh. It has a role as an antioxidant and a fundamental metabolite. It is a conjugate base of a 1,4-butanediammonium.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
butane-1,4-diamine
CAS number
110-60-1 CAS number cross-checked
EC number
203-782-3
Molecular formula
C4H12N2
UNII
V10TVZ52E4
MDL number
MFCD00008235
InChIKey
KIDHWZJUCRJVML-UHFFFAOYSA-N
InChI
InChI=1S/C4H12N2/c5-3-1-2-4-6/h1-6H2
SMILES (canonical and isomeric)
C(CCN)CN

Synonyms

  • 1,4-diaminobutane
  • 1,4-butanediamine
  • butane-1,4-diamine
  • tetramethylenediamine
  • Butylenediamine
  • Putrescin
  • 1,4-Butylenediamine
  • Tetramethyldiamine
  • 1,4-Tetramethylenediamine
  • 1,4 Butanediamine
  • 1,4 Diaminobutane
  • but-2-ynedinitrile
  • putrescina
  • Putreszin
  • Tetramethylendiamin
  • H2N(CH2)4NH2
  • Putrescine, free base
  • 1,4-Diamino-n-butane
  • Putrescine, NSC 60545, Putramine
  • Butane, 1,4-diamino-
  • Diaminobutane dihydrochloride
  • PUT
  • butylene amine
  • tetramethylendiamine
  • 4-amino-butyl-amine
Show all 34 synonyms
  • tetramethylene diamine
  • 1,4 diamino butane
  • 1,4-butane diamine
  • 1,4-diamino butane
  • 1i7c
  • 1i7m
  • 1,4-Diaminobutane, 99%
  • Butane,1,4-diamino
  • DivK1c_000716

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
Colorless oilexp.
Odour
Strong piperidine-like odorexp.
Melting point
27.5 °Cexp.
Boiling point
158.5 °Cexp.
Density
0.877 g/cm³ at 25 °Cexp.
Solubility
Soluble in water with strongly basic reactionexp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
88.15 g/molcalc.
Exact mass
88.10 Dacalc.
LogP (octanol/water)
-0.32calc.
Topological polar surface area
52.04 Ųcalc.
Hydrogen bond donors
2calc.
Hydrogen bond acceptors
2calc.
Rotatable bonds
3calc.
Heavy atoms
6calc.
Rings
0calc.
Aromatic rings
0calc.
Fraction sp3 carbons
1calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS02: Flammable
Flammable
GHS05: Corrosive
Corrosive
GHS06: Acute toxicity (severe)
Acute toxicity (severe)
GHS07: Harmful or irritant
Harmful or irritant
020NFPA 704 rating

Hazard statements

  • H226Flammable liquid and vapour.
  • H290May be corrosive to metals.
  • H302 + H312Harmful if swallowed. Harmful in contact with skin.
  • H302Harmful if swallowed.
  • H311Toxic in contact with skin.
  • H312Harmful in contact with skin.
  • H314Causes severe skin burns and eye damage.
  • H318Causes serious eye damage.
  • H330Fatal if inhaled.
  • H412Harmful to aquatic life with long lasting effects.
Precautionary statements (38)
  • P210Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
  • P233Keep container tightly closed.
  • P234Keep only in original packaging.
  • P240Ground and bond container and receiving equipment.
  • P241Use explosion-proof electrical, ventilating and lighting equipment.
  • P242Use non-sparking tools.
  • P243Take action to prevent static discharges.
  • P260Do not breathe dust, fume, gas, mist, vapours or spray.
  • P262Do not get in eyes, on skin, or on clothing.
  • P264Wash skin thoroughly after handling.
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P270Do not eat, drink or smoke when using this product.
  • P271Use only outdoors or in a well-ventilated area.
  • P273Avoid release to the environment.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P284In case of inadequate ventilation wear respiratory protection.
  • P301 + P317If swallowed: Get medical help.
  • P301 + P330 + P331If swallowed: Rinse mouth. Do not induce vomiting.
  • P302 + P352If on skin: Wash with plenty of water.
  • P302 + P361 + P354If on skin: Take off immediately all contaminated clothing. Immediately rinse with water for several minutes.
  • P303 + P361 + P353If on skin (or hair): Take off immediately all contaminated clothing. Rinse skin with water or shower.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P305 + P354 + P338If in eyes: Immediately rinse with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P316Get emergency medical help immediately.
  • P317Get medical help.
  • P320Specific treatment is urgent (see supplemental first aid instructions on the label).
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P330Rinse mouth.
  • P361 + P364Take off immediately all contaminated clothing. And wash it before reuse.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P363Wash contaminated clothing before reuse.
  • P370 + P378In case of fire: Use appropriate media to extinguish.
  • P390Absorb spillage to prevent material damage.
  • P403 + P233Store in a well-ventilated place. Keep container tightly closed.
  • P403 + P235Store in a well-ventilated place. Keep cool.
  • P405Store locked up.
  • P406Store in a corrosion resistant container with a resistant inner liner.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Putrescine suppliers

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All 66 suppliers
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Where suppliers are based

66 suppliers in 15 countries

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Putrescine price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

As a tool in biochemical research.

Chemical intermediate, complexing agent, catalyst in resin technology, synthesis of quaternary ammonium compounds.

Industrial uses: Corrosion inhibitor, Sealant (barrier), Intermediate, Other.

Roles

  • antioxidant
  • fundamental metabolite
  • metabolite

Pharmacology

Putrescine is a four carbon diamine produced during tissue decomposition by the decarboxylation of amino acids. Polyamines, including putrescine, may act as growth factors that promote cell division, however, putrescine is toxic at high doses.

How it is made

1,4-Diaminobutane can be produced from 1,4-dichloro-2-butene or 1,4-dihalobutane (obtainable from the reaction of butadiene or tetrahydrofuran with a halogen), preferably via the phthalimido compounds. Alternatively, 1,4-diaminobutane can be prepared by hydrogenating succinodinitrile. (Putrescine)

Putrescine is produced on industrial scale by hydrogenation of succinonitrile, which is produced by addition of hydrogen cyanide to acrylonitrile.

Regulatory status

Inventories, regulations and trade controls that list this substance

United States

  • TSCA inventory (USA)
    Status: Active in US commerce

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Putrescine is traded under.

HS 2921.29Indicative HS code

Acyclic polyamines and their derivatives, salts thereof, other

World exports in 2024
$1.16B
+1.0% vs 2023, imports $1.12B
2019 to 2024
Top exporters
  1. Japan16.6%
  2. China14.4%
  3. Netherlands13.6%
Top importers
  1. China15.2%
  2. United States11.2%
  3. Germany8.0%
Reported customs values in USD, not prices.Full trade data

The HS code shown for Putrescine is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Putrescine, based on the data on this page

What is Putrescine?

Putrescine is a four-carbon alkane-alpha,-diamine. It is obtained by the breakdown of amino acids and is responsible for the foul odour of putrefying flesh. It has a role as an antioxidant and a fundamental metabolite. It is a conjugate base of a 1,4-butanediammonium.

What is the CAS number of Putrescine?

The CAS registry number of Putrescine is 110-60-1.

What is the molecular formula and weight of Putrescine?

The molecular formula of Putrescine is C4H12N2 and its molar mass is 88.15 g/mol.

What is Putrescine used for?

As a tool in biochemical research. Chemical intermediate, complexing agent, catalyst in resin technology, synthesis of quaternary ammonium compounds. Industrial uses: Corrosion inhibitor, Sealant (barrier), Intermediate, Other.

Is Putrescine hazardous?

Putrescine carries the GHS signal word "Danger". Main hazards: flammable liquid and vapour, may be corrosive to metals, harmful if swallowed. harmful in contact with skin. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Putrescine?

Putrescine is usually classified under HS code 292129 (Acyclic polyamines and their derivatives, salts thereof, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Putrescine?

CompoundList lists 66 suppliers of Putrescine in United States, China, Germany, United Kingdom and 11 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Putrescine?

Suppliers quote Putrescine on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Putrescine

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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