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Respiratory, allergy and digestive drugs

Pyrilamine

Also known as Mepyramine, Pyranisamine, Dorantamin

CAS 91-84-9Formula C17H23N3OMolar mass 285.39 g/molEC 202-102-2
GHS signal word: Danger. Pictograms: Harmful or irritant, Serious health hazard 43 suppliers listed Drug substance
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Pyrilamine chemical structure, C17H23N3O, CAS 91-84-9
2D chemical structure

Key facts

What buyers check first

All properties
Appearance
Oily liquid
Melting point
143 to 143.5
Boiling point
201 °C
Density
1.074 at 70.5 °F - Denser than water, will sink
Solubility
1 G DISSOLVES IN ABOUT 0.4 ML WATER, SLIGHTLY SOL IN BENZENE, ETHER, 1 G DISSOLVES IN AB…
HS code
293339
Category
Respiratory, allergy and digestive drugs
Illustrative photo, closed amber glass reagent bottles on a laboratory bench
Typical packagingIllustrative packaging image, not the actual product

What is Pyrilamine?

Plain description, key identifiers and synonyms

Mepyramine is an ethylenediamine derivative that is ethylenediamine in which one of the amino nitrogens is substituted by two methyl groups and the remaining amino nitrogen is substituted by a 4-methoxybenzyl and a pyridin-2-yl group. It has a role as a H1-receptor antagonist. It is an ethylenediamine derivative and an aromatic ether.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
N'-[(4-methoxyphenyl)methyl]-N,N-dimethyl-N'-pyridin-2-ylethane-1,2-diamine
CAS number
91-84-9 CAS number cross-checkedOther or deprecated CAS: 102206-59-7
EC number
202-102-2
Molecular formula
C17H23N3O
UNII
HPE317O9TL
MDL number
MFCD00023451
InChIKey
YECBIJXISLIIDS-UHFFFAOYSA-N
InChI
InChI=1S/C17H23N3O/c1-19(2)12-13-20(17-6-4-5-11-18-17)14-15-7-9-16(21-3)10-8-15/h4-11H,12-14H2,1-3H3
SMILES (canonical and isomeric)
CN(C)CCN(CC1=CC=C(C=C1)OC)C2=CC=CC=N2

Synonyms

  • Mepyramine
  • Pyranisamine
  • Dorantamin
  • Mepiramine
  • Neoantergan
  • Anhistabs
  • Anhistol
  • Antalergan
  • Antallergan
  • Antamine
  • Copsamine
  • Harvamine
  • Histacap
  • Histalon
  • Histapyran
  • Histasan
  • Maranhist
  • Paraminyl
  • Statomin
  • Thylogen
  • Coradon
  • Dipane
  • Isamin
  • Kriptin
  • Mepyren
Show all 39 synonyms
  • Nyscaps
  • Parmal
  • Pyramal
  • Stamine
  • Stangen
  • Neo-Bridal
  • Afko-Hist
  • Mepyramin
  • PYRA
  • Mepiramina
  • Mepyraminum
  • Wait's green mountain antihistamine
  • RP 2786
  • N',N'-Dimethyl-N-(p-methoxybenzyl)-N-(2-pyridyl)ethylenediamine

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
Oily liquidexp.
Melting point
143 to 143.5exp.
Boiling point
201 °Cexp.
Density
1.074 at 70.5 °F - Denser than water, will sinkexp.
Solubility
1 G DISSOLVES IN ABOUT 0.4 ML WATER, SLIGHTLY SOL IN BENZENE, ETHER, 1 G DISSOLVES IN ABOUT 15 ML ABS ALCOHOL /MALEATE/exp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
285.39 g/molcalc.
Exact mass
285.1841 Dacalc.
LogP (octanol/water)
2.66calc.
Topological polar surface area
28.6 Ųcalc.
Hydrogen bond donors
0calc.
Hydrogen bond acceptors
4calc.
Rotatable bonds
7calc.
Heavy atoms
21calc.
Rings
2calc.
Aromatic rings
2calc.
Fraction sp3 carbons
0.35calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccc(CNc2ccccn2)cc1

c1ccc(CNc2ccccn2)cc1

2 rings, 14 atoms, the 2-(Benzylamino)pyridine ring system.

753 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS07: Harmful or irritant
Harmful or irritant
GHS08: Serious health hazard
Serious health hazard

Hazard statements

  • H302Harmful if swallowed.
  • H334May cause allergy or asthma symptoms or breathing difficulties if inhaled.
Precautionary statements (12)
  • P233Keep container tightly closed.
  • P260Do not breathe dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P270Do not eat, drink or smoke when using this product.
  • P271Use only outdoors or in a well-ventilated area.
  • P284In case of inadequate ventilation wear respiratory protection.
  • P301 + P317If swallowed: Get medical help.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P330Rinse mouth.
  • P342 + P316If experiencing respiratory symptoms: Get emergency medical help immediately.
  • P403Store in a well-ventilated place.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Pyrilamine suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 43 suppliers
30 of 30 offers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

43 suppliers in 11 countries

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Pyrilamine price

Indicative price range per kg from live supplier offers

No published prices right now

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Uses and applications

What the substance is used for, by industry and function

Veterinary medication:.

Pharmacological actions

  • Anti-Allergic Agents
  • Histamine H1 Antagonists
  • Sleep Aids, Pharmaceutical

Roles

  • H1-receptor antagonist
  • antagonist
  • histamine antagonist
  • histaminergic drug
  • neurotransmitter agent
  • pharmaceutical

How it is made

Prepared by condensing 2-(n-p-methoxybenzyl)-aminopyridine with dimethylaminoethyl chloride, or by condensing n,n-dimethylaminoethyl-alpha-aminopyridine with p-methoxybenzyl chloride in the presence of sodamide or lithamide.

Treatment of the pure base with an equimolar quantity of maleic acid yields the maleate. (Maleate)

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • Active ingredient in FDA approved drug labels

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Pyrilamine is traded under.

HS 2933.39Indicative HS code

Heterocyclic compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure…

World exports in 2024
$9.16B
−17.9% vs 2023, imports $10.6B
2019 to 2024
Top exporters
  1. China21.5%
  2. India * partner reported12.3%
  3. Ireland11.6%
Top importers
  1. Germany14.2%
  2. United States12.8%
  3. Brazil10.1%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Pyrilamine is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Pyrilamine, based on the data on this page

What is Pyrilamine?

Mepyramine is an ethylenediamine derivative that is ethylenediamine in which one of the amino nitrogens is substituted by two methyl groups and the remaining amino nitrogen is substituted by a 4-methoxybenzyl and a pyridin-2-yl group. It has a role as a H1-receptor antagonist.

What is the CAS number of Pyrilamine?

The CAS registry number of Pyrilamine is 91-84-9. Other or deprecated CAS numbers: 102206-59-7.

What is the molecular formula and weight of Pyrilamine?

The molecular formula of Pyrilamine is C17H23N3O and its molar mass is 285.39 g/mol.

What is Pyrilamine used for?

Veterinary medication:.

Is Pyrilamine hazardous?

Pyrilamine carries the GHS signal word "Danger". Main hazards: harmful if swallowed, may cause allergy or asthma symptoms or breathing difficulties if inhaled. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Pyrilamine?

Pyrilamine is usually classified under HS code 293339 (Compounds containing an unfused pyridine ring (whether or not hydrogenated) in the…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Pyrilamine?

CompoundList lists 43 suppliers of Pyrilamine in United States, China, Germany, Spain and 7 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Pyrilamine?

Suppliers quote Pyrilamine on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Pyrilamine

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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