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Key facts

What buyers check first

Appearance
Colorless to brown /srp: technical grade/
Melting point
-14.8 °C
Boiling point
237.7 °C
Density
Relative density (water = 1): 1.09
Flash point
99 °C
HS code
293349
Category
Corrosion inhibitors
UN number
UN 2656
Illustrative photo, a 1000 litre IBC tote of clear liquid in a warehouse
Typical packagingIllustrative packaging image, not the actual product

What is Quinoline?

Plain description, key identifiers and synonyms

Quinoline is the simplest member of the quinoline class of compounds, comprising a benzene ring ortho fused to C-2 and C-3 of a pyridine ring. It is a member of quinolines, a mancude organic heterobicyclic parent, an azaarene and an ortho-fused heteroarene.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
quinoline
CAS number
91-22-5 CAS number cross-checkedOther or deprecated CAS: 15793-82-5, 15793-83-6, 15793-84-7, 15793-85-8, 15793-86-9, 31177-31-8
EC number
202-051-6
Molecular formula
C9H7N
UNII
E66400VT9R
MDL number
MFCD00006736
InChIKey
SMWDFEZZVXVKRB-UHFFFAOYSA-N
InChI
InChI=1S/C9H7N/c1-2-6-9-8(4-1)5-3-7-10-9/h1-7H
SMILES (canonical and isomeric)
C1=CC=C2C(=C1)C=CC=N2

Synonyms

  • 1-Benzazine
  • Chinoline
  • Chinoleine
  • Chinolin
  • Quinolin
  • 1-Azanaphthalene
  • Leucol
  • Leukol
  • Benzopyridine
  • 2,3-Benzopyridine
  • Benzo[b]pyridine
  • Benzo(b)pyridine
  • USAF EK-218
  • 1-Benzine
  • Quinoline-3-D
  • Quinoline-4-D
  • Quinoline-5-D
  • Quinoline-6-D
  • Quinoline-7-D
  • Quinoline (8CI,9CI)
  • Benzopyridine (VAN)
  • hydroquinoline
  • Quinoline (tech grade)
  • Quinoline, >=97%
  • Quinoline, >=99%
Show all 31 synonyms
  • Quinoline > 90% grade
  • Quinoline, analytical standard
  • Quinoline, reagent grade, 96%
  • Quinoline, reagent grade, 98%
  • 1-Benzazine, 2,3-Benzopyridine
  • Quinoline, redistilled from glass

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
Colorless to brown /srp: technical grade/exp.
Odour
Penetrating odor, not as offensive as pyridineexp.
Melting point
-14.8 °Cexp.
Boiling point
237.7 °Cexp.
Density
Relative density (water = 1): 1.09exp.
Flash point
99 °Cexp.
Autoignition temperature
480 °Cexp.
Solubility
More sol in hot than cold water, sol in ethanol, ethyl ether, acetone, carbon disulfide and other common organic solvents.exp.
Vapour pressure
0.06 mm Hg @ 25 °Cexp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
129.16 g/molcalc.
Exact mass
129.0578 Dacalc.
LogP (octanol/water)
2.23calc.
Topological polar surface area
12.89 Ųcalc.
Hydrogen bond donors
0calc.
Hydrogen bond acceptors
1calc.
Rotatable bonds
0calc.
Heavy atoms
10calc.
Rings
2calc.
Aromatic rings
2calc.
Fraction sp3 carbons
0calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccc2ncccc2c1

c1ccc2ncccc2c1

2 rings, 10 atoms. This chemical is the scaffold itself.

21,766 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS07: Harmful or irritant
Harmful or irritant
GHS08: Serious health hazard
Serious health hazard
GHS09: Hazardous to the environment
Hazardous to the environment
120NFPA 704 rating

Hazard statements

  • H302Harmful if swallowed.
  • H312Harmful in contact with skin.
  • H315Causes skin irritation.
  • H319Causes serious eye irritation.
  • H341Suspected of causing genetic defects.
  • H350May cause cancer.
  • H411Toxic to aquatic life with long lasting effects.
Precautionary statements (19)
  • P203Obtain, read and follow all safety instructions before use.
  • P264Wash skin thoroughly after handling.
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P270Do not eat, drink or smoke when using this product.
  • P273Avoid release to the environment.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P301 + P317If swallowed: Get medical help.
  • P302 + P352If on skin: Wash with plenty of water.
  • P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P317Get medical help.
  • P318If exposed or concerned, get medical advice.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P330Rinse mouth.
  • P332 + P317If skin irritation occurs: Get medical help.
  • P337 + P317If eye irritation persists: Get medical help.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P391Collect spillage.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.
UN number
UN 2656
Transport hazard class
6.1
Packing group
III

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Quinoline suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 105 suppliers
30 of 30 offers

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Quinoline price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Manuf dyes, prepn hydroxyquinoline sulfate, q.v., niacin. As preservative for anatomical specimens. Solvent for resins abd terpenes.

Chem int for 8-hydroxyquinoline, a fungistat, chem int for pharmaceuticals-e.g., antiinfectives, corrosion inhibitor.

Used as ... a decarboxylation reagent.

Used in the manufacture of ... paints.

Quinoline is used mainly as an intermediate in the manufacture of other products.

Industrial uses: Corrosion inhibitor, Absorbent.

Functional uses

  • Dye
  • Flavouring and nutrient
  • Fragrance
  • Pigment
  • Surface modifier

How it is made

Prepd by the Skaup synthesis of heating aniline with glycerol and nitrobenzene in presence of sulfuric acid: Clarke, Davis, Org. Syn. coll. vol. I, 478 (2nd ed., 1941) 478: alternate syntheses: Manske, Chem Rev. 20, 113 (1942), Bergstrom, ibis, 35, 150 (1944). Process based on interaction of aniline with acetaldehyde and a formaldehyde hemiacetal: Cislak, Wheeler, US 3020281 (1962 to Reilly Tar & Chem.).

Quinoline may be extracted from bone oil...

Isolation from the chemical oil fraction of coal tar distillates.

Regulatory status

Inventories, regulations and trade controls that list this substance

Europe

  • EU harmonised classification (CLP Annex VI)
    Index no: 613-281-00-5

Health and food

  • EU Cosmetics Regulation Annex II, prohibited in cosmetics
    Name: Quinoline, Ref no: 1527, Annex ref: II/1527

United States

  • TSCA inventory (USA)
    Status: Active in US commerce

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Quinoline is traded under.

HS 2933.49Indicative HS code

Compounds containing in the structure a quinoline or isoquinoline ring-system (whether…

World exports in 2024
$939M
−14.6% vs 2023, imports $1.48B
2019 to 2024
Top exporters
  1. China30.1%
  2. India * partner reported16.7%
  3. Switzerland * partner reported14.1%
Top importers
  1. United Kingdom19.2%
  2. Germany16.0%
  3. Romania8.3%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Quinoline is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Quinoline, based on the data on this page

What is Quinoline?

Quinoline is the simplest member of the quinoline class of compounds, comprising a benzene ring ortho fused to C-2 and C-3 of a pyridine ring. It is a member of quinolines, a mancude organic heterobicyclic parent, an azaarene and an ortho-fused heteroarene.

What is the CAS number of Quinoline?

The CAS registry number of Quinoline is 91-22-5. Other or deprecated CAS numbers: 15793-82-5, 15793-83-6, 15793-84-7.

What is the molecular formula and weight of Quinoline?

The molecular formula of Quinoline is C9H7N and its molar mass is 129.16 g/mol.

What is Quinoline used for?

Manuf dyes, prepn hydroxyquinoline sulfate, q.v., niacin. As preservative for anatomical specimens. Solvent for resins abd terpenes. Chem int for 8-hydroxyquinoline, a fungistat, chem int for pharmaceuticals-e.g., antiinfectives, corrosion inhibitor. Used as ... a decarboxylation reagent. Used in the manufacture of ...

Is Quinoline hazardous?

Quinoline carries the GHS signal word "Danger". Main hazards: harmful if swallowed, harmful in contact with skin, causes skin irritation. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Quinoline?

Quinoline is usually classified under HS code 293349 (Compounds containing in the structure a quinoline or isoquinoline ring-system (whether…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Quinoline?

CompoundList lists 105 suppliers of Quinoline in China, United States, India, United Kingdom and 16 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Quinoline in India?

6 suppliers in India list Quinoline on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Quinoline?

Suppliers quote Quinoline on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Quinoline

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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