Quinoline
Also known as 1-Benzazine, Chinoline, Chinoleine
Key facts
What buyers check first
- Appearance
- Colorless to brown /srp: technical grade/
- Melting point
- -14.8 °C
- Boiling point
- 237.7 °C
- Density
- Relative density (water = 1): 1.09
- Flash point
- 99 °C
- HS code
- 293349
- Category
- Corrosion inhibitors
- UN number
- UN 2656

What is Quinoline?
Plain description, key identifiers and synonyms
Quinoline is the simplest member of the quinoline class of compounds, comprising a benzene ring ortho fused to C-2 and C-3 of a pyridine ring. It is a member of quinolines, a mancude organic heterobicyclic parent, an azaarene and an ortho-fused heteroarene.
Identifiers
Registry numbers, names and line notations, tap to copy
- IUPAC name
- quinoline
- CAS number
- 91-22-5 CAS number cross-checkedOther or deprecated CAS: 15793-82-5, 15793-83-6, 15793-84-7, 15793-85-8, 15793-86-9, 31177-31-8
- EC number
- 202-051-6
- Molecular formula
- C9H7N
- UNII
- E66400VT9R
- MDL number
- MFCD00006736
- InChIKey
- SMWDFEZZVXVKRB-UHFFFAOYSA-N
- InChI
- InChI=1S/C9H7N/c1-2-6-9-8(4-1)5-3-7-10-9/h1-7H
- SMILES (canonical and isomeric)
- C1=CC=C2C(=C1)C=CC=N2
Synonyms
- 1-Benzazine
- Chinoline
- Chinoleine
- Chinolin
- Quinolin
- 1-Azanaphthalene
- Leucol
- Leukol
- Benzopyridine
- 2,3-Benzopyridine
- Benzo[b]pyridine
- Benzo(b)pyridine
- USAF EK-218
- 1-Benzine
- Quinoline-3-D
- Quinoline-4-D
- Quinoline-5-D
- Quinoline-6-D
- Quinoline-7-D
- Quinoline (8CI,9CI)
- Benzopyridine (VAN)
- hydroquinoline
- Quinoline (tech grade)
- Quinoline, >=97%
- Quinoline, >=99%
Show all 31 synonymsShow fewer synonyms
- Quinoline > 90% grade
- Quinoline, analytical standard
- Quinoline, reagent grade, 96%
- Quinoline, reagent grade, 98%
- 1-Benzazine, 2,3-Benzopyridine
- Quinoline, redistilled from glass
Physical and chemical properties
Measured values and descriptors computed from the structure
Physical and chemical properties
Measured values, check the supplier specification for your grade
| Appearance | Colorless to brown /srp: technical grade/exp.Measured value |
|---|---|
| Odour | Penetrating odor, not as offensive as pyridineexp.Measured value |
| Melting point | -14.8 °Cexp.Measured value |
| Boiling point | 237.7 °Cexp.Measured value |
| Density | Relative density (water = 1): 1.09exp.Measured value |
| Flash point | 99 °Cexp.Measured value |
| Autoignition temperature | 480 °Cexp.Measured value |
| Solubility | More sol in hot than cold water, sol in ethanol, ethyl ether, acetone, carbon disulfide and other common organic solvents.exp.Measured value |
| Vapour pressure | 0.06 mm Hg @ 25 °Cexp.Measured value |
Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.
Computed descriptors
Calculated from the structure, useful for screening and formulation
| Molecular weight | 129.16 g/molcalc.Computed value |
|---|---|
| Exact mass | 129.0578 Dacalc.Computed value |
| LogP (octanol/water) | 2.23calc.Computed value |
| Topological polar surface area | 12.89 Ųcalc.Computed value |
| Hydrogen bond donors | 0calc.Computed value |
| Hydrogen bond acceptors | 1calc.Computed value |
| Rotatable bonds | 0calc.Computed value |
| Heavy atoms | 10calc.Computed value |
| Rings | 2calc.Computed value |
| Aromatic rings | 2calc.Computed value |
| Fraction sp3 carbons | 0calc.Computed value |
| Formal charge | 0calc.Computed value |
| Stereocentres | 0calc.Computed value |
| Lipinski rule of five | Passes (0 violations)calc.Computed value |
Calculated for screening. Confirm critical figures with the supplier.
Murcko scaffold
The ring system that remains when every side chain is removed
c1ccc2ncccc2c1
2 rings, 10 atoms. This chemical is the scaffold itself.
21,766 other chemicals share this scaffoldSafety and hazards
GHS classification summary, not a safety data sheet
Hazard statements
- H302Harmful if swallowed.
- H312Harmful in contact with skin.
- H315Causes skin irritation.
- H319Causes serious eye irritation.
- H341Suspected of causing genetic defects.
- H350May cause cancer.
- H411Toxic to aquatic life with long lasting effects.
Precautionary statements (19)
- P203Obtain, read and follow all safety instructions before use.
- P264Wash skin thoroughly after handling.
- P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
- P270Do not eat, drink or smoke when using this product.
- P273Avoid release to the environment.
- P280Wear protective gloves, protective clothing, eye protection and face protection.
- P301 + P317If swallowed: Get medical help.
- P302 + P352If on skin: Wash with plenty of water.
- P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
- P317Get medical help.
- P318If exposed or concerned, get medical advice.
- P321Specific treatment (see supplemental first aid instructions on the label).
- P330Rinse mouth.
- P332 + P317If skin irritation occurs: Get medical help.
- P337 + P317If eye irritation persists: Get medical help.
- P362 + P364Take off contaminated clothing. And wash it before reuse.
- P391Collect spillage.
- P405Store locked up.
- P501Dispose of contents and container in accordance with local regulations.
- UN number
- UN 2656
- Transport hazard class
- 6.1
- Packing group
- III
GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.
Full safety data and first aidQuinoline suppliers
Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings
- India, Navi Mumbai ManufacturerUnclaimed profileQuinolineGrade, purity and minimum order on requestPrice on request
- China, ShanghaiUnclaimed profileQuinolineGrade, purity and minimum order on requestPrice on request
- France, CourbevoieUnclaimed profileQuinolineGrade, purity and minimum order on requestPrice on request
- China, AnshanUnclaimed profileQuinolineGrade, purity and minimum order on requestPrice on request
- Price on request
- ChinaUnclaimed profileQuinolineGrade, purity and minimum order on requestPrice on request
- China, Cn ManufacturerUnclaimed profileQuinolineGrade, purity and minimum order on requestPrice on request
- Price on request
- China, WuhanUnclaimed profileQuinolineGrade, purity and minimum order on requestPrice on request
Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.
Where suppliers are based
105 suppliers in 20 countries
- China36
- United States30
- India6
- United Kingdom5
- Germany4
- Canada2
- and 14 more countries
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Quinoline price
Indicative price range per kg from live supplier offers
Suppliers quote this chemical on request. Send one free request and compare quotes side by side.
Uses and applications
What the substance is used for, by industry and function
Manuf dyes, prepn hydroxyquinoline sulfate, q.v., niacin. As preservative for anatomical specimens. Solvent for resins abd terpenes.
Chem int for 8-hydroxyquinoline, a fungistat, chem int for pharmaceuticals-e.g., antiinfectives, corrosion inhibitor.
Used as ... a decarboxylation reagent.
Used in the manufacture of ... paints.
Quinoline is used mainly as an intermediate in the manufacture of other products.
Industrial uses: Corrosion inhibitor, Absorbent.
Functional uses
- Dye
- Flavouring and nutrient
- Fragrance
- Pigment
- Surface modifier
How it is made
Prepd by the Skaup synthesis of heating aniline with glycerol and nitrobenzene in presence of sulfuric acid: Clarke, Davis, Org. Syn. coll. vol. I, 478 (2nd ed., 1941) 478: alternate syntheses: Manske, Chem Rev. 20, 113 (1942), Bergstrom, ibis, 35, 150 (1944). Process based on interaction of aniline with acetaldehyde and a formaldehyde hemiacetal: Cislak, Wheeler, US 3020281 (1962 to Reilly Tar & Chem.).
Quinoline may be extracted from bone oil...
Isolation from the chemical oil fraction of coal tar distillates.
Regulatory status
Inventories, regulations and trade controls that list this substance
Europe
- EU harmonised classification (CLP Annex VI)Index no: 613-281-00-5
Health and food
- EU Cosmetics Regulation Annex II, prohibited in cosmeticsName: Quinoline, Ref no: 1527, Annex ref: II/1527
United States
- TSCA inventory (USA)Status: Active in US commerce
HS code and trade data
Customs classification and reported world trade statistics
Global trade
World import and export statistics for the HS code Quinoline is traded under.
Compounds containing in the structure a quinoline or isoquinoline ring-system (whether…
- China30.1%
- India * partner reported16.7%
- Switzerland * partner reported14.1%
- United Kingdom19.2%
- Germany16.0%
- Romania8.3%
* Partner reported figures, a lower bound.
The HS code shown for Quinoline is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.
Frequently asked questions
Quick answers about Quinoline, based on the data on this page
What is Quinoline?
What is the CAS number of Quinoline?
What is the molecular formula and weight of Quinoline?
What is Quinoline used for?
Is Quinoline hazardous?
What is the HS code of Quinoline?
Where can I buy Quinoline?
Where can I buy Quinoline in India?
What is the price of Quinoline?
Guides for buyers
Practical guides that help when you source, ship or handle Quinoline
- Guide, SafetyHow to read a safety data sheet in 10 minutesA section by section method to pull the essentials out of any 16 section SDS: identity, hazards, composition, storage, PPE, properties, transport and emergency measures.Read
- Guide, Trade and logisticsShipping dangerous goods: UN numbers, classes and packing groupsHow the UN dangerous goods system works for chemicals, from the nine classes and UN numbers to packing groups, UN packaging marks, labels, documents and segregation.Read
- Guide, SafetyGHS pictograms, signal words and hazard statements explainedA practical guide to the nine GHS pictograms, the signal words Danger and Warning, H and P statements, and how to read a chemical label in seconds.Read
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