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Cardiovascular and metabolic drugs

Repaglinide

Also known as Prandin, Repaglinida, AG-EE 623 ZW

CAS 135062-02-1Formula C27H36N2O4Molar mass 452.60 g/molEC 629-921-1
GHS signal word: Warning. Pictograms: Serious health hazard 112 suppliers listed Drug substance
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Repaglinide chemical structure, C27H36N2O4, CAS 135062-02-1
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
135062-02-1
Formula
C27H36N2O4
Molar mass
452.60 g/mol
EC number
629-921-1
HS code
293339
Category
Cardiovascular and metabolic drugs

What is Repaglinide?

Plain description, key identifiers and synonyms

Repaglinide is a member of piperidines.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
2-ethoxy-4-[2-[[(1S)-3-methyl-1-(2-piperidin-1-ylphenyl)butyl]amino]-2-oxoethyl]benzoic acid
CAS number
135062-02-1 CAS number cross-checked
EC number
629-921-1
Molecular formula
C27H36N2O4
UNII
668Z8C33LU
MDL number
MFCD00906179
InChIKey
FAEKWTJYAYMJKF-QHCPKHFHSA-N
InChI
InChI=1S/C27H36N2O4/c1-4-33-25-17-20(12-13-22(25)27(31)32)18-26(30)28-23(16-19(2)3)21-10-6-7-11-24(21)29-14-8-5-9-15-29/h6-7,10-13,17,19,23H,4-5,8-9,14-16,18H2,1-3H3,(H,28,30)(H,31,32)/t23-/m0/s1
Canonical SMILES
CCOc1cc(CC(=O)NC(CC(C)C)c2ccccc2N2CCCCC2)ccc1C(=O)O
Isomeric SMILES
CCOC1=C(C=CC(=C1)CC(=O)N[C@@H](CC(C)C)C2=CC=CC=C2N3CCCCC3)C(=O)O

Synonyms

  • Prandin
  • Repaglinida
  • AG-EE 623 ZW
  • GlucoNorm
  • AG-EE 388 ZW
  • Repaglinidum
  • AGEE-623ZW
  • enyglid
  • 2-ethoxy-4-[2-[[(1S)-3-methyl-1-(2-piperidin-1-ylphenyl)butyl]amino]-2-oxoethyl]benzoic acid
  • (+)-2-Ethoxy-alpha-(((S)-alpha-isobutyl-o-piperidinobenzyl)carbamoyl)-p-toluic acid
  • repaglinide impurity E
  • 2-ethoxy-4-({[(1S)-3-methyl-1-[2-(piperidin-1-yl)phenyl]butyl]carbamoyl}methyl)benzoic acid
  • Benzoic acid, 2-ethoxy-4-(2-((3-methyl-1-(2-(1-piperidinyl)phenyl)butyl)amino)-2-oxoethyl)-, (S)-
  • repa-glinide
  • 2-ethoxy-4-(2-{[(1S)-3-methyl-1-(2-piperidin-1-ylphenyl)butyl]amino}-2-oxoethyl)benzoic acid
  • AG-EE 388
  • 2-ethoxy-4-(2-((3-methyl-1-(2-(1-piperidinyl)phenyl)butyl)amino)-2-oxoethyl)benzoic acid
  • (+)-repaglinide
  • 2-ethoxy-4-((((1S)-3-methyl-1-(2-(piperidin-1-yl)phenyl)butyl)carbamoyl)methyl)benzoic acid
  • 2-ethoxy-4-(2-(((1S)-3-methyl-1-(2-piperidin-1-ylphenyl)butyl)amino)-2-oxoethyl)benzoic acid
  • 2-ethoxy-N-(alpha-(2-methyl-1-propyl)-2-piperidinobenzyl)-4-carbamoylmethylbenzoic acid
  • (S)-2-ethoxy-4-(2-((3-methyl-1-(2-(1-piperidinyl)-phenyl)butyl)amino)-2-oxoethyl)-benzoic acid
  • 2-ethoxy-4-(2-(((1R)-3-methyl-1-(2-(1-piperidinyl)phenyl)butyl)amino)-2-oxoethyl)benzoic acid
  • Benzoic Acid, 2-ethoxy-4-(2-((3-methyl-1-(2-(1-piperidinyl)phenyl)butyl)amino)-2-oxoethyl)-,(S)-
  • NovoNorm
Show all 35 synonyms
  • (S)-2-Ethoxy-4-(2-((3-methyl-1-(2-(piperidin-1-yl)phenyl)butyl)amino)-2-oxoethyl)benzoic acid
  • AG-EE 623ZW
  • (S)-2-Ethoxy-4-[2-[[3-methyl-1-[2-(piperidin-1-yl)phenyl]butyl]amino]-2-oxoethyl]benzoic acid
  • (S)-(+)-2-Ethoxy-4-[N-[1-(2-piperidinophenyl)-3-methyl-1-butyl]aminocarbonylmethyl]benzoic acid
  • (S)-2-ethoxy-4-(2-(3-methyl-1-(2-(piperidin-1-yl)phenyl)butylamino)-2-oxoethyl)benzoic acid
  • 2-ethoxy-4-[2-({(1S)-3-methyl-1-[2-(piperidin-1-yl)phenyl]butyl}amino)-2-oxoethyl]benzoic acid
  • Actulin
  • Surepost
  • (-)-Repaglinide
  • Reglin

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
452.60 g/molcalc.
Exact mass
452.2675 Dacalc.
LogP (octanol/water)
5.22calc.
Topological polar surface area
78.87 Ųcalc.
Hydrogen bond donors
2calc.
Hydrogen bond acceptors
4calc.
Rotatable bonds
10calc.
Heavy atoms
33calc.
Rings
3calc.
Aromatic rings
2calc.
Fraction sp3 carbons
0.48calc.
Formal charge
0calc.
Stereocentres
1calc.
Lipinski rule of five
Passes (1 violation)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C(Cc1ccccc1)NCc1ccccc1N1CCCCC1

O=C(Cc1ccccc1)NCc1ccccc1N1CCCCC1

3 rings, 23 atoms.

22 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS08: Serious health hazard
Serious health hazard

Hazard statements

  • H361Suspected of damaging fertility or the unborn child.
  • H362May cause harm to breast-fed children.
  • H412Harmful to aquatic life with long lasting effects.
Precautionary statements (10)
  • P203Obtain, read and follow all safety instructions before use.
  • P260Do not breathe dust, fume, gas, mist, vapours or spray.
  • P263Avoid contact during pregnancy and while nursing.
  • P264Wash skin thoroughly after handling.
  • P270Do not eat, drink or smoke when using this product.
  • P273Avoid release to the environment.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P318If exposed or concerned, get medical advice.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Repaglinide suppliers

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All 112 suppliers
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Where suppliers are based

112 suppliers in 19 countries

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Repaglinide price

Indicative price range per kg from live supplier offers

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Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

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Uses and applications

What the substance is used for, by industry and function

Industries and functions

Pharmacological actions

  • Hypoglycemic Agents

Roles

  • anti-anaemic agent
  • antiatherosclerotic agent
  • antidyskinesia agent
  • antihypertensive agent
  • antiinfective agent
  • antimalarial
  • antimicrobial agent
  • antimicrobial drug
  • antineoplastic agent
  • antiparasitic agent
  • antiparkinson drug
  • antiplasmodial drug
  • antiprotozoal drug
  • antirheumatic drug
  • cardiovascular drug
  • hypoglycemic agent
  • pharmaceutical

Pharmacology

Repaglinide is a Glinide. The mechanism of action of repaglinide is as a Potassium Channel Antagonist.

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • Active ingredient in FDA approved drug labels

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Repaglinide is traded under.

HS 2933.39Indicative HS code

Heterocyclic compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure…

World exports in 2024
$9.16B
−17.9% vs 2023, imports $10.6B
2019 to 2024
Top exporters
  1. China21.5%
  2. India * partner reported12.3%
  3. Ireland11.6%
Top importers
  1. Germany14.2%
  2. United States12.8%
  3. Brazil10.1%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Repaglinide is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Repaglinide, based on the data on this page

What is Repaglinide?

Repaglinide is a member of piperidines.

What is the CAS number of Repaglinide?

The CAS registry number of Repaglinide is 135062-02-1.

What is the molecular formula and weight of Repaglinide?

The molecular formula of Repaglinide is C27H36N2O4 and its molar mass is 452.60 g/mol.

What is Repaglinide used for?

Known uses and roles of Repaglinide include antidiabetics in pharmaceuticals, anti-anaemic agent, antiatherosclerotic agent, antidyskinesia agent, antihypertensive agent and 14 more.

Is Repaglinide hazardous?

Repaglinide carries the GHS signal word "Warning". Main hazards: suspected of damaging fertility or the unborn child, may cause harm to breast-fed children, harmful to aquatic life with long lasting effects. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Repaglinide?

Repaglinide is usually classified under HS code 293339 (Compounds containing an unfused pyridine ring (whether or not hydrogenated) in the…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Repaglinide?

CompoundList lists 112 suppliers of Repaglinide in United States, China, India, Germany and 15 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Repaglinide in India?

19 suppliers in India list Repaglinide on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Repaglinide?

Suppliers quote Repaglinide on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Repaglinide

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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