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Vitamins and nutraceutical actives

Retinal

Also known as all-trans-Retinal, trans-Retinal, retinaldehyde

CAS 116-31-4Formula C20H28OMolar mass 284.44 g/molEC 204-135-8
GHS signal word: Danger. Pictograms: Harmful or irritant, Serious health hazard 77 suppliers listed
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Retinal chemical structure, C20H28O, CAS 116-31-4
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
116-31-4
Formula
C20H28O
Molar mass
284.44 g/mol
EC number
204-135-8
HS code
293621
Category
Vitamins and nutraceutical actives

What is Retinal?

Plain description, key identifiers and synonyms

All-trans-retinal is a retinal in which all four exocyclic double bonds have E- (trans-) geometry. It has a role as a gap junctional intercellular communication inhibitor, a mouse metabolite and a human metabolite. It is a vitamin A and a retinal.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraenal
CAS number
116-31-4 CAS number cross-checkedOther or deprecated CAS: 472-86-6
EC number
204-135-8
Molecular formula
C20H28O
UNII
RR725D715M
MDL number
MFCD00001550
INCI name
RETINAL
InChIKey
NCYCYZXNIZJOKI-OVSJKPMPSA-N
InChI
InChI=1S/C20H28O/c1-16(8-6-9-17(2)13-15-21)11-12-19-18(3)10-7-14-20(19,4)5/h6,8-9,11-13,15H,7,10,14H2,1-5H3/b9-6+,12-11+,16-8+,17-13+
Canonical SMILES
CC(C=CC=C(C)C=CC1=C(C)CCCC1(C)C)=CC=O
Isomeric SMILES
CC1=C(C(CCC1)(C)C)/C=C/C(=C/C=C/C(=C/C=O)/C)/C

Synonyms

  • all-trans-Retinal
  • trans-Retinal
  • retinaldehyde
  • vitamin A aldehyde
  • retinene
  • axerophthal
  • all-E-Retinal
  • E-Retinal
  • Retinene 1
  • all-trans-Retinaldehyde
  • Vitamin A1 aldehyde
  • all-trans-Vitamin A aldehyde
  • all-trans-Retinene
  • Retinyl aldehyde
  • Retinal, all-trans
  • (2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenal
  • (2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraenal
  • 3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-Nonatetraenal
  • 3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexenyl)nona-2,4,6,8-tetraenal
  • Retinyl Aldehydde
  • All trans retinal
  • Aldehydde, Retinyl
  • 11 cis Retinal
  • 11 trans Retinal
  • Aldehyde, Vitamin A
Show all 38 synonyms
  • all trans-Retinal
  • all-trans retinal
  • Retinal, all-trans-
  • trans-Vitamin A aldehyde
  • Retinaldehyde (VAN)
  • 13-Cis retinal
  • Tocopherol, alpha
  • retinaldehyd
  • retinylaldehyde
  • Retinin
  • epsilon-Retinal
  • Retinene1
  • tocopherol alpha-

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
284.44 g/molcalc.
Exact mass
284.214 Dacalc.
LogP (octanol/water)
5.72calc.
Topological polar surface area
17.07 Ųcalc.
Hydrogen bond donors
0calc.
Hydrogen bond acceptors
1calc.
Rotatable bonds
5calc.
Heavy atoms
21calc.
Rings
1calc.
Aromatic rings
0calc.
Fraction sp3 carbons
0.45calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (1 violation)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, C1=CCCCC1

C1=CCCCC1

1 ring, 6 atoms, the Cyclohexene ring system.

5,167 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS07: Harmful or irritant
Harmful or irritant
GHS08: Serious health hazard
Serious health hazard

Hazard statements

  • H302Harmful if swallowed.
  • H315Causes skin irritation.
  • H360May damage fertility or the unborn child.
  • H413May cause long lasting harmful effects to aquatic life.
Precautionary statements (14)
  • P203Obtain, read and follow all safety instructions before use.
  • P264Wash skin thoroughly after handling.
  • P270Do not eat, drink or smoke when using this product.
  • P273Avoid release to the environment.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P301 + P317If swallowed: Get medical help.
  • P302 + P352If on skin: Wash with plenty of water.
  • P318If exposed or concerned, get medical advice.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P330Rinse mouth.
  • P332 + P317If skin irritation occurs: Get medical help.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Retinal suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 77 suppliers
30 of 30 offers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

77 suppliers in 12 countries

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Retinal price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

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Uses and applications

What the substance is used for, by industry and function

Cosmetic ingredient, INCI name RETINAL(skin conditioning)

Roles

  • animal metabolite
  • eukaryotic metabolite
  • gap junctional intercellular communication inhibitor
  • human metabolite
  • mammalian metabolite
  • metabolite
  • mouse metabolite

Functional uses

  • Softener and conditioner

Cosmetic functions

  • Skin conditioning

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • EU cosmetic ingredient inventory

United States

  • TSCA inventory (USA)
    Status: Active in US commerce

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Retinal is traded under.

HS 2936.21Indicative HS code

Vitamins A and their derivatives

World exports in 2024
$621M
+16.4% vs 2023, imports $528M
2019 to 2024
Top exporters
  1. China26.7%
  2. United States25.5%
  3. Switzerland * partner reported21.4%
Top importers
  1. United States16.7%
  2. Germany8.7%
  3. Netherlands5.0%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Retinal is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Retinal, based on the data on this page

What is Retinal?

All-trans-retinal is a retinal in which all four exocyclic double bonds have E- (trans-) geometry. It has a role as a gap junctional intercellular communication inhibitor, a mouse metabolite and a human metabolite. It is a vitamin A and a retinal.

What is the CAS number of Retinal?

The CAS registry number of Retinal is 116-31-4. Other or deprecated CAS numbers: 472-86-6.

What is the molecular formula and weight of Retinal?

The molecular formula of Retinal is C20H28O and its molar mass is 284.44 g/mol.

What is Retinal used for?

Known uses and roles of Retinal include vitamins and supplements in pharmaceuticals, skin conditioning agents in cosmetics and personal care, vitamins, minerals and nutrients in food and beverage, feed vitamins in animal feed and nutrition, animal metabolite and 8 more.

Is Retinal hazardous?

Retinal carries the GHS signal word "Danger". Main hazards: harmful if swallowed, causes skin irritation, may damage fertility or the unborn child. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Retinal?

Retinal is usually classified under HS code 293621 (Vitamins A and their derivatives). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Retinal?

CompoundList lists 77 suppliers of Retinal in United States, China, Germany, United Kingdom and 8 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Retinal?

Suppliers quote Retinal on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Retinal

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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