Ribostamycin
Also known as Vistamycin, Ribostamicina, Ribostamycine
Key facts
What buyers check first
- CAS number
- 25546-65-0
- Formula
- C17H34N4O10
- Molar mass
- 454.48 g/mol
- EC number
- 247-091-5
- HS code
- 293219
- Category
- Antibiotics and anti-infectives
What is Ribostamycin?
Plain description, key identifiers and synonyms
Ribostamycin is an amino cyclitol glycoside that is 4,6-diaminocyclohexane-1,2,3-triol having a 2,6-diamino-2,6-dideoxy-alpha-D-glucosyl residue attached at position 1 and a beta-D-ribosyl residue attached at position 2. It is an antibiotic produced by Streptomyces ribosidificus (formerly S. thermoflavus). It has a role as a metabolite, an antimicrobial agent and an antibacterial drug. It is an amino cyclitol glycoside and an aminoglycoside antibiotic. It is a conjugate base of a ribostamycin(4+).
Ribostamycin is an aminoglycoside antibiotic.
Identifiers
Registry numbers, names and line notations, tap to copy
- IUPAC name
- (2R,3S,4R,5R,6R)-5-amino-2-(aminomethyl)-6-[(1R,2R,3S,4R,6S)-4,6-diamino-2-[(2S,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]oxy-3-hydroxycyclohexyl]oxyoxane-3,4-diol
- CAS number
- 25546-65-0 CAS number cross-checked
- EC number
- 247-091-5
- Molecular formula
- C17H34N4O10
- UNII
- 2Q5JOU7T53
- InChIKey
- NSKGQURZWSPSBC-VVPCINPTSA-N
- InChI
- InChI=1S/C17H34N4O10/c18-2-6-10(24)12(26)8(21)16(28-6)30-14-5(20)1-4(19)9(23)15(14)31-17-13(27)11(25)7(3-22)29-17/h4-17,22-27H,1-3,18-21H2/t4-,5+,6-,7-,8-,9+,10-,11-,12-,13-,14-,15-,16-,17+/m1/s1
- Canonical SMILES
- NCC1OC(OC2C(N)CC(N)C(O)C2OC2OC(CO)C(O)C2O)C(N)C(O)C1O
- Isomeric SMILES
- C1[C@H]([C@@H]([C@H]([C@@H]([C@H]1N)O[C@@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CN)O)O)N)O[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O)O)O)N
Synonyms
- Vistamycin
- Ribostamicina
- Ribostamycine
- Ribostamycinum
- ribostamycin A
- SF 733
- (1R,2R,3R,4R,6S)-4,6-diamino-3-hydroxy-2-(beta-D-ribofuranosyloxy)cyclohexyl 2,6-diamino-2,6-dideoxy-alpha-D-glucopyranoside
- D-Streptamine, O-2,6-diamino-2,6-dideoxy-alpha-D-glucopyranosyl-(1-4)-O-(beta-D-ribofuranosyl-(1-5))-2-deoxy-
- 2-Deoxy-4-O-(2,6-diamino-2,6-dideoxy-alpha-D-glucopyranosyl)-5-O-(beta-D-ribofuranosyl)-streptamine
- Hetangmycin
- Xylostatin
- Antibiotic SF 733
- Ribastamin
- Dekamycin IV
- Bu 1709
- Ribostamycin (INN)
- (1R,2R,3S,4R,6S)-4,6-diamino-3-hydroxy-2-(beta-D-ribofuranosyloxy)cyclohexyl 2,6-diamino-2,6-dideoxy-alpha-D-glucopyranoside
- RIO
- Ribostamycin, Vistamycin
- D-Streptamine, O-2,6-diamino-2,6-dideoxy-alpha-D-glucopyranosyl-(1-4)- O-(beta-D-ribofuranosyl-(1-5))-2-deoxy-
- O-2,6-Diamino-2,6-dideoxy-alpha-D-glucopyranosyl-(1->4)-O-(beta-D-ribofuranosyl-(1->5))-2-deoxystreptamine
- O-2,6-Diamino-2,6-dideoxy-alpha-D-glucopyranosyl-(1-4)-O-(beta-D-ribofuranosyl-(1-5))-2-deoxystreptamine
- D-Streptamine, o-2,6-diamino-2,6-dideoxy-alpha-d-glucopyranosyl-(1->4)-o-(beta-d-ribofuranosyl-(1->5))-2-deoxy-
- O-2,6-Diamino-2,6-dideoxy-alpha-D-glucopyranosyl-(1->4)-O-[beta-D-ribofuranosyl-(1->5)]-2-deoxy-D-streptamine
Physical and chemical properties
Measured values and descriptors computed from the structure
Physical and chemical properties
Measured values, check the supplier specification for your grade
No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.
Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.
Computed descriptors
Calculated from the structure, useful for screening and formulation
| Molecular weight | 454.48 g/molcalc.Computed value |
|---|---|
| Exact mass | 454.2275 Dacalc.Computed value |
| LogP (octanol/water) | -6.65calc.Computed value |
| Topological polar surface area | 262.4 ร
ยฒcalc.Computed value |
| Hydrogen bond donors | 10calc.Computed value |
| Hydrogen bond acceptors | 14calc.Computed value |
| Rotatable bonds | 6calc.Computed value |
| Heavy atoms | 31calc.Computed value |
| Rings | 3calc.Computed value |
| Aromatic rings | 0calc.Computed value |
| Fraction sp3 carbons | 1calc.Computed value |
| Formal charge | 0calc.Computed value |
| Stereocentres | 14calc.Computed value |
| Lipinski rule of five | Fails (2 violations)calc.Computed value |
Calculated for screening. Confirm critical figures with the supplier.
Murcko scaffold
The ring system that remains when every side chain is removed
Safety and hazards
GHS classification summary, not a safety data sheet
No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.
GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.
Ribostamycin suppliers
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Ribostamycin price
Indicative price range per kg from live supplier offers
Suppliers quote this chemical on request. Send one free request and compare quotes side by side.
Uses and applications
What the substance is used for, by industry and function
Industries and functions
Pharmacological actions
- Anti-Bacterial Agents
Roles
- antibacterial agent
- antibacterial drug
- antiinfective agent
- antimicrobial agent
- antimicrobial drug
- metabolite
- pharmaceutical
Pharmacology
Ribostamycin is an aminoglycoside antibiotic isolated from Streptomyces ribosidificus.
Regulatory status
Inventories, regulations and trade controls that list this substance
No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.
HS code and trade data
Customs classification and reported world trade statistics
Global trade
World import and export statistics for the HS code Ribostamycin is traded under.
Compounds containing an unfused furan ring (whether or not hydrogenated) in theโฆ
The HS code shown for Ribostamycin is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.
Frequently asked questions
Quick answers about Ribostamycin, based on the data on this page
What is Ribostamycin?
What is the CAS number of Ribostamycin?
What is the molecular formula and weight of Ribostamycin?
What is Ribostamycin used for?
Is Ribostamycin hazardous?
What is the HS code of Ribostamycin?
Where can I buy Ribostamycin?
What is the price of Ribostamycin?
Guides for buyers
Practical guides that help when you source, ship or handle Ribostamycin
- Article, QualityPharma grades explained: IP vs BP vs USP vs EPWhat the Indian, British, US and European pharmacopoeias are, how their monographs differ, what multi grade claims mean and why a grade alone does not make a product fit for medicines.Read
- Article, SourcingHow to write an RFQ that gets fast and accurate quotesWhat suppliers need to quote quickly and comparably: exact product identity, quantity and packing, delivery terms, documents, samples and payment, with a ready to use template.Read
- Guide, Trade and logisticsHS codes for chemicals and why they matterHow the Harmonized System classifies chemicals, the chapters that matter, the rules for chemically defined compounds and mixtures, and practical steps to find the right code.Read
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