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Antibiotics and anti-infectives

Neomycin

Also known as Fradiomycin, Neomas, Nivemycin

CAS 1404-04-2Formula C23H46N6O13Molar mass 614.65 g/molEC 204-292-2
GHS signal word: Danger. Pictograms: Harmful or irritant, Serious health hazard 60 suppliers listed Drug substance
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Neomycin chemical structure, C23H46N6O13, CAS 1404-04-2
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
1404-04-2
Formula
C23H46N6O13
Molar mass
614.65 g/mol
Solubility
Soluble in water solutions up to 250 mg/mL may be prepared
HS code
294190
Category
Antibiotics and anti-infectives

What is Neomycin?

Plain description, key identifiers and synonyms

Framycetin is a tetracyclic antibacterial agent derived from neomycin, being a glycoside ester of neamine and neobiosamine B. It has a role as an antibacterial drug, an allergen and an Escherichia coli metabolite. It is a conjugate base of a framycetin(6+).

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(2R,3S,4R,5R,6R)-5-amino-2-(aminomethyl)-6-[(1R,2R,3S,4R,6S)-4,6-diamino-2-[(2S,3R,4S,5R)-4-[(2R,3R,4R,5S,6S)-3-amino-6-(aminomethyl)-4,5-dihydroxyoxan-2-yl]oxy-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]oxy-3-hydroxycyclohexyl]oxyoxane-3,4-diol
CAS number
1404-04-2 CAS number cross-checkedOther or deprecated CAS: 11004-65-2, 119-04-0
EC numbers
204-292-2, 215-766-3
Molecular formula
C23H46N6O13
UNII
4BOC774388, I16QD7X297
MDL number
MFCD09788228
InChIKey
PGBHMTALBVVCIT-VCIWKGPPSA-N
InChI
InChI=1S/C23H46N6O13/c24-2-7-13(32)15(34)10(28)21(37-7)40-18-6(27)1-5(26)12(31)20(18)42-23-17(36)19(9(4-30)39-23)41-22-11(29)16(35)14(33)8(3-25)38-22/h5-23,30-36H,1-4,24-29H2/t5-,6+,7-,8+,9-,10-,11-,12+,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23+/m1/s1
Canonical SMILES
NCC1OC(OC2C(CO)OC(OC3C(O)C(N)CC(N)C3OC3OC(CN)C(O)C(O)C3N)C2O)C(N)C(O)C1O
Isomeric SMILES
C1[C@H]([C@@H]([C@H]([C@@H]([C@H]1N)O[C@@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CN)O)O)N)O[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O[C@@H]4[C@@H]([C@H]([C@@H]([C@@H](O4)CN)O)O)N)O)O)N

Synonyms

  • Fradiomycin
  • Neomas
  • Nivemycin
  • Myacyne
  • Neolate
  • Vonamycin powder V
  • Neomin
  • Neomicina
  • Neomycine
  • Neomycinum
  • Pimavecort
  • Vonamycin
  • Kaomycine
  • Neomycin Complex
  • Framycetin
  • Neomycin b
  • Soframycin
  • Actilin
  • Framygen
  • Fradiomycin B
  • Enterfram
  • Framicetina
  • Framycetine
  • Fradiomycinum
  • Framycetinum
Show all 38 synonyms
  • Antibiotic 10676
  • Neomycin B Hexaacetate
  • Neobrettin
  • Actiline
  • Framidal
  • Framycin
  • Francetin
  • Dekamycin iii
  • Soframycine
  • Framycetin (INN)
  • Neomycin Trisulfate Hydrate Deuterated
  • Antibiotique ef 185
  • Neomcin

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Solubility
Soluble in water solutions up to 250 mg/mL may be preparedexp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
614.65 g/molcalc.
Exact mass
614.3123 Dacalc.
LogP (octanol/water)
-8.9calc.
Topological polar surface area
353.1 Ųcalc.
Hydrogen bond donors
13calc.
Hydrogen bond acceptors
19calc.
Rotatable bonds
9calc.
Heavy atoms
42calc.
Rings
4calc.
Aromatic rings
0calc.
Fraction sp3 carbons
1calc.
Formal charge
0calc.
Stereocentres
19calc.
Lipinski rule of five
Fails (3 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, C1CCC(OC2COC(OC3CCCCC3OC3CCCCO3)C2)OC1

C1CCC(OC2COC(OC3CCCCC3OC3CCCCO3)C2)OC1

4 rings, 26 atoms.

49 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS07: Harmful or irritant
Harmful or irritant
GHS08: Serious health hazard
Serious health hazard

Hazard statements

  • H302Harmful if swallowed.
  • H317May cause an allergic skin reaction.
  • H334May cause allergy or asthma symptoms or breathing difficulties if inhaled.
Precautionary statements (19)
  • P233Keep container tightly closed.
  • P260Do not breathe dust, fume, gas, mist, vapours or spray.
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P270Do not eat, drink or smoke when using this product.
  • P271Use only outdoors or in a well-ventilated area.
  • P272Contaminated work clothing should not be allowed out of the workplace.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P284In case of inadequate ventilation wear respiratory protection.
  • P301 + P317If swallowed: Get medical help.
  • P302 + P352If on skin: Wash with plenty of water.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P330Rinse mouth.
  • P333 + P317If skin irritation or rash occurs: Get medical help.
  • P342 + P316If experiencing respiratory symptoms: Get emergency medical help immediately.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P403Store in a well-ventilated place.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Neomycin suppliers

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All 60 suppliers
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Where suppliers are based

60 suppliers in 15 countries

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Neomycin price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Broad-spectrum antibiotic.

Used for bladder irrigation ... to prevent bacteriuria and bacteremia associated with the use of indwelling catheters.

Veterinary bactericidal drug.

Pharmacological actions

  • Anti-Bacterial Agents
  • Protein Synthesis Inhibitors

Roles

  • Escherichia coli metabolite
  • aetiopathogenetic role
  • allergen
  • antibacterial agent
  • antibacterial drug
  • antiinfective agent
  • antimicrobial agent
  • antimicrobial drug
  • antineoplastic agent
  • bacterial metabolite
  • metabolite
  • nasal decongestant
  • ophthalmology drug
  • pharmaceutical
  • prokaryotic metabolite

Pharmacology

Neomycin is an Aminoglycoside Antibacterial.

How it is made

Produced by Streptomyces fradiae.

Antibiotics can broadly be classified into the following categories: aminoglycosides, beta-lactams, macrolides, and tetracyclines, of which only the tetracylines do not use ion-exchange resins in their recovery from fermentation broths. (Ion-exchange resins)

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • Active ingredient in FDA approved drug labels

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Neomycin is traded under.

HS 2941.90Indicative HS code

Antibiotics, other

World exports in 2024
$6.39B
+2.3% vs 2023, imports $6.97B
2019 to 2024
Top exporters
  1. China39.7%
  2. United States11.3%
  3. Switzerland * partner reported10.9%
Top importers
  1. Italy15.0%
  2. India * partner reported12.0%
  3. China8.7%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Neomycin is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Neomycin, based on the data on this page

What is Neomycin?

Framycetin is a tetracyclic antibacterial agent derived from neomycin, being a glycoside ester of neamine and neobiosamine B. It has a role as an antibacterial drug, an allergen and an Escherichia coli metabolite. It is a conjugate base of a framycetin(6+).

What is the CAS number of Neomycin?

The CAS registry number of Neomycin is 1404-04-2. Other or deprecated CAS numbers: 11004-65-2, 119-04-0.

What is the molecular formula and weight of Neomycin?

The molecular formula of Neomycin is C23H46N6O13 and its molar mass is 614.65 g/mol.

What is Neomycin used for?

Broad-spectrum antibiotic. Used for bladder irrigation ... to prevent bacteriuria and bacteremia associated with the use of indwelling catheters. Veterinary bactericidal drug.

Is Neomycin hazardous?

Neomycin carries the GHS signal word "Danger". Main hazards: harmful if swallowed, may cause an allergic skin reaction, may cause allergy or asthma symptoms or breathing difficulties if inhaled. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Neomycin?

Neomycin is usually classified under HS code 294190 (Antibiotics, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Neomycin?

CompoundList lists 60 suppliers of Neomycin in United States, China, India, Germany and 11 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Neomycin in India?

6 suppliers in India list Neomycin on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Neomycin?

Suppliers quote Neomycin on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Neomycin

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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