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Antibiotics and anti-infectives

Paromomycin

Also known as Aminosidin, catenulin, Monomycin A

CAS 7542-37-2Formula C23H45N5O14Molar mass 615.63 g/molEC 231-423-0
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Paromomycin chemical structure, C23H45N5O14, CAS 7542-37-2
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
7542-37-2
Formula
C23H45N5O14
Molar mass
615.63 g/mol
EC number
231-423-0
HS code
294190
Category
Antibiotics and anti-infectives

What is Paromomycin?

Plain description, key identifiers and synonyms

Paromomycin is an amino cyclitol glycoside that is the 1-O-(2-amino-2-deoxy-alpha-D-glucopyranoside) and the 3-O-(2,6-diamino-2,6-dideoxy-beta-L-idopyranosyl)-beta-D-ribofuranoside of 4,6-diamino-2,3-dihydroxycyclohexane (the 1R,2R,3S,4R,6S diastereoisomer). It is obtained from various Streptomyces species. A broad-spectrum antibiotic, it is used (generally as the sulfate salt) for the treatment of acute and chronic intestinal protozoal infections, but is not effective for extraintestinal protozoal infections. It is also used as a therapeutic against visceral leishmaniasis. It has a role as an antiparasitic agent, an anthelminthic drug, an antiprotozoal drug and an antibacterial drug. It is an amino cyclitol glycoside and an aminoglycoside antibiotic. It is functionally related to a streptamine. It is a conjugate base of a paromomycin(5+).

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(2S,3S,4R,5R,6R)-5-amino-2-(aminomethyl)-6-[(2R,3S,4R,5S)-5-[(1R,2R,3S,5R,6S)-3,5-diamino-2-[(2S,3R,4R,5S,6R)-3-amino-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-6-hydroxycyclohexyl]oxy-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl]oxyoxane-3,4-diol
CAS number
7542-37-2 CAS number cross-checkedOther or deprecated CAS: 1263-89-4, 134235-09-9
EC number
231-423-0
Molecular formula
C23H45N5O14
UNII
61JJC8N5ZK
InChIKey
UOZODPSAJZTQNH-LSWIJEOBSA-N
InChI
InChI=1S/C23H45N5O14/c24-2-7-13(32)15(34)10(27)21(37-7)41-19-9(4-30)39-23(17(19)36)42-20-12(31)5(25)1-6(26)18(20)40-22-11(28)16(35)14(33)8(3-29)38-22/h5-23,29-36H,1-4,24-28H2/t5-,6+,7+,8-,9-,10-,11-,12+,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23+/m1/s1
Canonical SMILES
NCC1OC(OC2C(CO)OC(OC3C(O)C(N)CC(N)C3OC3OC(CO)C(O)C(O)C3N)C2O)C(N)C(O)C1O
Isomeric SMILES
C1[C@H]([C@@H]([C@H]([C@@H]([C@H]1N)O[C@@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)O)N)O[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O[C@@H]4[C@@H]([C@H]([C@@H]([C@@H](O4)CN)O)O)N)O)O)N

Synonyms

  • Aminosidin
  • catenulin
  • Monomycin A
  • Neomycin E
  • Hydroxymycin
  • Crestomycin
  • Paucimycin
  • Aminosidine
  • Paromomycine
  • Estomycin
  • Quintomycin C
  • Paromomycin I
  • Zygomycin A1
  • Gabromycin
  • Paromomicina
  • Antibiotic 503-3
  • Paromomycinum
  • Paucimycinum
  • Antibiotic SF 767B
  • Antibiotic sf-767b
  • Paramomycin
  • D-Streptamine, O-2-amino-2-deoxy-alpha-D-glucopyranosyl-(1-4)-O-(O-2,6-diamino-2,6-dideoxy-beta-L-idopyranosyl-(1-3)-beta-D-ribofuranosyl-(1-5))-2-deoxy-
  • Streptamine, O-2,6-diamino-2,6-dideoxy-beta-L-idopyranosyl-(1-3)-O-beta-D-ribofuranosyl-(1-5)-O-(2-amino-2-deoxy-alpha-D-glucopyranosyl-(1-4))-2-deoxy-
  • aminosidina
  • Paromomycin, beta D Glucopyranosyl
Show all 37 synonyms
  • beta-D-Glucopyranosyl-Isomer Paromomycin
  • o-2,6-Diamino-2,6-dideoxy-beta-l-idopyranosyl-(1->3)-o-beta-d-ribofuranosyl-(1->5)-o-(2-amino-2-deoxy-alpha-d-glucopyranosyl-(1->4))-2-deoxystreptamine
  • o-2-Amino-2-deoxy-alpha-d-glucopyranosyl-(1->4)-o-(O-2,6-diamino-2,6-dideoxy-beta-l-idopyranosyl-(1->3)-beta-d-ribofuranosyl-(1->5))-2-deoxy-d-streptamine
  • Paramomycin Sulfate
  • Humatin
  • Humycin
  • Paromomycin (INN)
  • Aminosidine I
  • Hydroxymycin sulfate
  • Antibiotic 2230D
  • Amminosidin
  • Paromomycin Deuterated Acetic Acid Salt

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
615.63 g/molcalc.
Exact mass
615.2963 Dacalc.
LogP (octanol/water)
-8.86calc.
Topological polar surface area
347.3 Ųcalc.
Hydrogen bond donors
13calc.
Hydrogen bond acceptors
19calc.
Rotatable bonds
9calc.
Heavy atoms
42calc.
Rings
4calc.
Aromatic rings
0calc.
Fraction sp3 carbons
1calc.
Formal charge
0calc.
Stereocentres
19calc.
Lipinski rule of five
Fails (3 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, C1CCC(OC2COC(OC3CCCCC3OC3CCCCO3)C2)OC1

C1CCC(OC2COC(OC3CCCCC3OC3CCCCO3)C2)OC1

4 rings, 26 atoms.

49 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Paromomycin suppliers

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All 13 suppliers
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Where suppliers are based

13 suppliers in 7 countries

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Paromomycin price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Use classes: Pharmaceuticals.

Pharmacological actions

  • Anti-Bacterial Agents
  • Antiprotozoal Agents

Roles

  • anthelminthic drug
  • antibacterial agent
  • antibacterial drug
  • antiinfective agent
  • antileishmanial agent
  • antimicrobial agent
  • antimicrobial drug
  • antiparasitic agent
  • antiprotozoal drug
  • pharmaceutical

Pharmacology

Paromomycin is an Antiprotozoal.

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • Active ingredient in FDA approved drug labels

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Paromomycin is traded under.

HS 2941.90Indicative HS code

Antibiotics, other

World exports in 2024
$6.39B
+2.3% vs 2023, imports $6.97B
2019 to 2024
Top exporters
  1. China39.7%
  2. United States11.3%
  3. Switzerland * partner reported10.9%
Top importers
  1. Italy15.0%
  2. India * partner reported12.0%
  3. China8.7%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Paromomycin is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Paromomycin, based on the data on this page

What is Paromomycin?

Paromomycin is an amino cyclitol glycoside that is the 1-O-(2-amino-2-deoxy-alpha-D-glucopyranoside) and the 3-O-(2,6-diamino-2,6-dideoxy-beta-L-idopyranosyl)-beta-D-ribofuranoside of 4,6-diamino-2,3-dihydroxycyclohexane (the 1R,2R,3S,4R,6S diastereoisomer). It is obtained from various Streptomyces species.

What is the CAS number of Paromomycin?

The CAS registry number of Paromomycin is 7542-37-2. Other or deprecated CAS numbers: 1263-89-4, 134235-09-9.

What is the molecular formula and weight of Paromomycin?

The molecular formula of Paromomycin is C23H45N5O14 and its molar mass is 615.63 g/mol.

What is Paromomycin used for?

Use classes: Pharmaceuticals.

Is Paromomycin hazardous?

No GHS hazard classification for Paromomycin is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Paromomycin?

Paromomycin is usually classified under HS code 294190 (Antibiotics, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Paromomycin?

CompoundList lists 13 suppliers of Paromomycin in China, Netherlands, Australia, Canada and 3 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Paromomycin?

Suppliers quote Paromomycin on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Paromomycin

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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