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Nucleosides and nucleotides

Rintatolimod

Also known as (rI(n).r(C(12)U)n), Ampligen, Atvogen

CAS 38640-92-5Formula C28H40N9O25P3Molar mass 995.59 g/mol
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Rintatolimod chemical structure, C28H40N9O25P3, CAS 38640-92-5
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
38640-92-5
Formula
C28H40N9O25P3
Molar mass
995.59 g/mol
HS code
293499
Category
Nucleosides and nucleotides

What is Rintatolimod?

Plain description, key identifiers and synonyms

Rintatolimod is a synthetic derivative of inosinic acid with antiretroviral and immunomodulatory properties. Atvogen acts through a number of pathways to stimulate intracellular antiviral activity of the immune system: it stimulates interferon production, activates the oligoadenylate synthase-RNase L pathway, stimulates natural killer cell activity, and acts as a non-mitogenic stimulator of the immune system. This agent also inhibits replication of human immunodeficiency virus (HIV) in vitro. (NCI04)

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
[(2R,3S,4R,5R)-5-(4-amino-2-oxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate, [(2R,3S,4R,5R)-3,4-dihydroxy-5-(6-oxo-1H-purin-9-yl)oxolan-2-yl]methyl dihydrogen phosphate, [(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate
CAS number
38640-92-5 CAS number cross-checked
Molecular formula
C28H40N9O25P3
InChIKey
KNUXHTWUIVMBBY-JRJYXWDASA-N
InChI
InChI=1S/C10H13N4O8P.C9H14N3O8P.C9H13N2O9P/c15-6-4(1-21-23(18,19)20)22-10(7(6)16)14-3-13-5-8(14)11-2-12-9(5)17;10-5-1-2-12(9(15)11-5)8-7(14)6(13)4(20-8)3-19-21(16,17)18;12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(20-8)3-19-21(16,17)18/h2-4,6-7,10,15-16H,1H2,(H,11,12,17)(H2,18,19,20);1-2,4,6-8,13-14H,3H2,(H2,10,11,15)(H2,16,17,18);1-2,4,6-8,13-14H,3H2,(H,10,12,15)(H2,16,17,18)/t4-,6-,7-,10-;2*4-,6-,7-,8-/m111/s1
Canonical SMILES
Nc1ccn(C2OC(COP(=O)(O)O)C(O)C2O)c(=O)n1.O=c1[nH]cnc2c1ncn2C1OC(COP(=O)(O)O)C(O)C1O.O=c1ccn(C2OC(COP(=O)(O)O)C(O)C2O)c(=O)[nH]1
Isomeric SMILES
C1=CN(C(=O)N=C1N)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)(O)O)O)O.C1=CN(C(=O)NC1=O)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)(O)O)O)O.C1=NC2=C(C(=O)N1)N=CN2[C@H]3[C@@H]([C@@H]([C@H](O3)COP(=O)(O)O)O)O

Synonyms

  • (rI(n).r(C(12)U)n)
  • Ampligen
  • Atvogen
  • Poly I: Poly C12U
  • Poly(5')-inosinyl-(3'->) duplex with poly(dodecakis(3')-cytidylyl-(5'->)3')-uridylyl-(5'->)
  • rintatolimodum

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
995.59 g/molcalc.
Exact mass
995.1348 Dacalc.
LogP (octanol/water)
-7.33calc.
Topological polar surface area
528.7 Ųcalc.
Hydrogen bond donors
15calc.
Hydrogen bond acceptors
23calc.
Rotatable bonds
12calc.
Heavy atoms
65calc.
Rings
7calc.
Aromatic rings
4calc.
Fraction sp3 carbons
0.54calc.
Formal charge
0calc.
Stereocentres
12calc.
Components
3calc.
Lipinski rule of five
Fails (3 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=c1[nH]cnc2c1ncn2C1CCCO1

O=c1[nH]cnc2c1ncn2C1CCCO1

3 rings, 15 atoms, the 9-(Oxolan-2-yl)-3H-purin-6-one ring system.

973 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Rintatolimod suppliers

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Rintatolimod price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Pharmacological actions

  • Antiviral Agents

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Rintatolimod is traded under.

HS 2934.99Indicative HS code

Nucleic acids and their salts, other heterocyclic compounds, not elsewhere classified in heading 2934

World exports in 2024
$26.7B
+15.0% vs 2023, imports $26.3B
2019 to 2024
Top exporters
  1. Ireland26.3%
  2. China15.7%
  3. Singapore10.3%
Top importers
  1. United States24.5%
  2. Germany23.1%
  3. Japan4.5%
Reported customs values in USD, not prices.Full trade data

The HS code shown for Rintatolimod is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Rintatolimod, based on the data on this page

What is Rintatolimod?

Rintatolimod is a synthetic derivative of inosinic acid with antiretroviral and immunomodulatory properties.

What is the CAS number of Rintatolimod?

The CAS registry number of Rintatolimod is 38640-92-5.

What is the molecular formula and weight of Rintatolimod?

The molecular formula of Rintatolimod is C28H40N9O25P3 and its molar mass is 995.59 g/mol.

What is Rintatolimod used for?

Known uses and roles of Rintatolimod include antiviral agents.

Is Rintatolimod hazardous?

No GHS hazard classification for Rintatolimod is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Rintatolimod?

Rintatolimod is usually classified under HS code 293499 (Nucleic acids and their salts, whether or not chemically defined, other heterocyclic…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Rintatolimod?

Post a free request on CompoundList and suppliers of Rintatolimod will send you quotes. Your contact details stay private until you accept a quote.

What is the price of Rintatolimod?

Suppliers quote Rintatolimod on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Rintatolimod

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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