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Antibiotics and anti-infectives

Rolitetracycline

Also known as Syntetrin, Reverin, Rolitetraciclina

CAS 751-97-3Formula C27H33N3O8Molar mass 527.57 g/molEC 212-031-9
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Rolitetracycline chemical structure, C27H33N3O8, CAS 751-97-3
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
751-97-3
Formula
C27H33N3O8
Molar mass
527.57 g/mol
EC number
212-031-9
HS code
294130
Category
Antibiotics and anti-infectives

What is Rolitetracycline?

Plain description, key identifiers and synonyms

Rolitetracycline is a derivative of tetracycline in which the amide function is substituted with a pyrrolidinomethyl group. It has a role as an antiprotozoal drug, an antibacterial drug, a protein synthesis inhibitor and a prodrug. It is a tertiary alpha-hydroxy ketone and a member of tetracyclines.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(4S,4aS,5aS,6S,12aR)-4-(dimethylamino)-1,6,10,11,12a-pentahydroxy-6-methyl-3,12-dioxo-N-(pyrrolidin-1-ylmethyl)-4,4a,5,5a-tetrahydrotetracene-2-carboxamide
CAS number
751-97-3 CAS number cross-checked
EC number
212-031-9
Molecular formula
C27H33N3O8
UNII
GH9IW85221
MDL number
MFCD00864995
InChIKey
IKQRPFTXKQQLJF-IAHYZSEUSA-N
InChI
InChI=1S/C27H33N3O8/c1-26(37)13-7-6-8-16(31)17(13)21(32)18-14(26)11-15-20(29(2)3)22(33)19(24(35)27(15,38)23(18)34)25(36)28-12-30-9-4-5-10-30/h6-8,14-15,20,31-32,35,37-38H,4-5,9-12H2,1-3H3,(H,28,36)/t14-,15-,20-,26+,27-/m0/s1
Canonical SMILES
CN(C)C1C(=O)C(C(=O)NCN2CCCC2)=C(O)C2(O)C(=O)C3=C(O)c4c(O)cccc4C(C)(O)C3CC12
Isomeric SMILES
C[C@@]1([C@H]2C[C@H]3[C@@H](C(=O)C(=C([C@]3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)NCN5CCCC5)N(C)C)O

Synonyms

  • Syntetrin
  • Reverin
  • Rolitetraciclina
  • Synterin
  • Velacycline
  • Rolitetracyclinum
  • Pyrrolidino-methyl-tetracycline
  • N-(Pyrrolidinomethyl)tetracycline
  • Bristacin
  • N-(1-Pyrrolidinylmethyl)-tetracycline
  • SQ 15,659
  • Transcycline
  • Rolitetracycline (Technical Grade)
  • Solvocillin
  • (4S,4aS,5aS,6S,12aR)-4-(dimethylamino)-1,6,10,11,12a-pentahydroxy-6-methyl-3,12-dioxo-N-(pyrrolidin-1-ylmethyl)-4,4a,5,5a-tetrahydrotetracene-2-carboxamide
  • Prm-TC
  • Superciclin
  • Synotodecin
  • 4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-N-(1-pyrrolidinylmethyl)-2-naphthacenecarboxamide
  • Velacicline
  • Syntetrex
  • Pirrolidinometil-tetraciclina
  • pyrrolidinylmethyltetracycline
  • Kinteto
  • AAT 4
Show all 28 synonyms
  • Tetracycline, pyrrolidinomethyl-
  • n-Pyrrolidino-methyl-tetracycline
  • Synterin (TN)

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
527.57 g/molcalc.
Exact mass
527.2268 Dacalc.
LogP (octanol/water)
0.31calc.
Topological polar surface area
170.9 Ųcalc.
Hydrogen bond donors
6calc.
Hydrogen bond acceptors
10calc.
Rotatable bonds
4calc.
Heavy atoms
38calc.
Rings
5calc.
Aromatic rings
1calc.
Fraction sp3 carbons
0.52calc.
Formal charge
0calc.
Stereocentres
5calc.
Lipinski rule of five
Fails (2 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C1CC2CC3Cc4ccccc4C=C3C(=O)C2C=C1C(=O)NCN1CCCC1

O=C1CC2CC3Cc4ccccc4C=C3C(=O)C2C=C1C(=O)NCN1CCCC1

5 rings, 29 atoms.

13 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Rolitetracycline suppliers

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Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

1 supplier in 1 country

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Rolitetracycline price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

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Uses and applications

What the substance is used for, by industry and function

Roles

  • antibacterial agent
  • antibacterial drug
  • antiinfective agent
  • antimicrobial agent
  • antimicrobial drug
  • antiparasitic agent
  • antiprotozoal drug
  • enzyme inhibitor
  • pathway inhibitor
  • pharmaceutical
  • pro-agent
  • prodrug
  • protein synthesis inhibitor

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Rolitetracycline is traded under.

HS 2941.30Indicative HS code

Tetracyclines and their derivatives, salts thereof

World exports in 2024
$565M
+0.2% vs 2023, imports $539M
2019 to 2024
Top exporters
  1. China66.0%
  2. Italy10.7%
  3. Portugal7.2%
Top importers
  1. United States11.6%
  2. India * partner reported8.9%
  3. Italy7.7%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Rolitetracycline is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Rolitetracycline, based on the data on this page

What is Rolitetracycline?

Rolitetracycline is a derivative of tetracycline in which the amide function is substituted with a pyrrolidinomethyl group. It has a role as an antiprotozoal drug, an antibacterial drug, a protein synthesis inhibitor and a prodrug. It is a tertiary alpha-hydroxy ketone and a member of tetracyclines.

What is the CAS number of Rolitetracycline?

The CAS registry number of Rolitetracycline is 751-97-3.

What is the molecular formula and weight of Rolitetracycline?

The molecular formula of Rolitetracycline is C27H33N3O8 and its molar mass is 527.57 g/mol.

What is Rolitetracycline used for?

Known uses and roles of Rolitetracycline include antibacterials and antibiotics in pharmaceuticals, antibacterial agent, antibacterial drug, antiinfective agent, antimicrobial agent and 9 more.

Is Rolitetracycline hazardous?

No GHS hazard classification for Rolitetracycline is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Rolitetracycline?

Rolitetracycline is usually classified under HS code 294130 (Tetracyclines and their derivatives, salts thereof). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Rolitetracycline?

CompoundList lists 1 supplier of Rolitetracycline in Australia. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Rolitetracycline?

Suppliers quote Rolitetracycline on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Rolitetracycline

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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