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Antibiotics and anti-infectives

Roxithromycin

Also known as Rulide, Rulid, RU 28965

CAS 80214-83-1Formula C41H76N2O15Molar mass 837.06 g/molEC 617-007-5
GHS signal word: Warning. Pictograms: Harmful or irritant 58 suppliers listed
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Roxithromycin chemical structure, C41H76N2O15, CAS 80214-83-1
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
80214-83-1
Formula
C41H76N2O15
Molar mass
837.06 g/mol
EC number
617-007-5
HS code
294150
Category
Antibiotics and anti-infectives

What is Roxithromycin?

Plain description, key identifiers and synonyms

Roxithromycin is semisynthetic derivative of erythromycin A. It has a role as an antibacterial drug. It is a macrolide, an erythromycin derivative and a semisynthetic derivative. It is functionally related to an erythromycin A.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(3R,4S,5S,6R,7R,9R,10E,11S,12R,13S,14R)-6-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-14-ethyl-7,12,13-trihydroxy-4-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-10-(2-methoxyethoxymethoxyimino)-3,5,7,9,11,13-hexamethyl-oxacyclotetradecan-2-one
CAS number
80214-83-1 CAS number cross-checked
EC number
617-007-5
Molecular formula
C41H76N2O15
UNII
21KOF230FA
InChIKey
RXZBMPWDPOLZGW-XMRMVWPWSA-N
InChI
InChI=1S/C41H76N2O15/c1-15-29-41(10,49)34(45)24(4)31(42-53-21-52-17-16-50-13)22(2)19-39(8,48)36(58-38-32(44)28(43(11)12)18-23(3)54-38)25(5)33(26(6)37(47)56-29)57-30-20-40(9,51-14)35(46)27(7)55-30/h22-30,32-36,38,44-46,48-49H,15-21H2,1-14H3/b42-31+/t22-,23-,24+,25+,26-,27+,28+,29-,30+,32-,33+,34-,35+,36-,38+,39-,40-,41-/m1/s1
Canonical SMILES
CCC1OC(=O)C(C)C(OC2CC(C)(OC)C(O)C(C)O2)C(C)C(OC2OC(C)CC(N(C)C)C2O)C(C)(O)CC(C)C(=NOCOCCOC)C(C)C(O)C1(C)O
Isomeric SMILES
CC[C@@H]1[C@@]([C@@H]([C@H](/C(=N/OCOCCOC)/[C@@H](C[C@@]([C@@H]([C@H]([C@@H]([C@H](C(=O)O1)C)O[C@H]2C[C@@]([C@H]([C@@H](O2)C)O)(C)OC)C)O[C@H]3[C@@H]([C@H](C[C@H](O3)C)N(C)C)O)(C)O)C)C)O)(C)O

Synonyms

  • Rulide
  • Rulid
  • RU 28965
  • RU 965
  • (9E)-erythromycin 9-(O-((2-methoxyethoxy)methyl)oxime)
  • Erythromycin, 9-(O-((2-methoxyethoxy)methyl)oxime), (9E)-
  • Infectoroxit
  • Erythromycin, 9-[O-[(2-methoxyethoxy)methyl]oxime], (9E)-
  • Roxi-paed 1A Pharma
  • Roxitromycin
  • Roxitromycine
  • 9-(2',5'-Dioxahexyloxyimino)erythromycin
  • (9E)-Erythromycin, 9-(O-((2-methoxyethoxy)methyl)oxime)
  • Roxithromycine
  • Roxithromycinum
  • Roxitromicina
  • Erythromycin 9-(O-((2-methoxyethoxy)methyl)oxime)
  • 9-(O-((2-Methoxyethoxy)methyl)oxime)erythromycin
  • Erythromycin 9-[O-[(2-methoxyethoxy)methyl]oxime]
  • (E)-roxithromycin
  • Erythromycin, 9-[O-[(2-methoxyethoxy)methyl]oxime], (9E)- (9CI)
  • Rulide (TN)
  • 9-[O-[(2-Methoxyethoxy)methyl]oxime]erythromycin
  • Cirumycin,
  • Macrosil,
Show all 31 synonyms
  • Rotramin,
  • Roxitrol,
  • Abbotic,
  • Azuril,
  • Roxithromycin CRS
  • Antibiotic RU 28965,

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
837.06 g/molcalc.
Exact mass
836.5246 Dacalc.
LogP (octanol/water)
2.21calc.
Topological polar surface area
216.9 Ųcalc.
Hydrogen bond donors
5calc.
Hydrogen bond acceptors
17calc.
Rotatable bonds
13calc.
Heavy atoms
58calc.
Rings
3calc.
Aromatic rings
0calc.
Fraction sp3 carbons
0.95calc.
Formal charge
0calc.
Stereocentres
18calc.
Lipinski rule of five
Fails (2 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, N=C1CCCCOC(=O)CC(OC2CCCCO2)CC(OC2CCCCO2)CCC1

N=C1CCCCOC(=O)CC(OC2CCCCO2)CC(OC2CCCCO2)CCC1

3 rings, 30 atoms.

75 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant

Hazard statements

  • H302Harmful if swallowed.
Precautionary statements (5)
  • P264Wash skin thoroughly after handling.
  • P270Do not eat, drink or smoke when using this product.
  • P301 + P317If swallowed: Get medical help.
  • P330Rinse mouth.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Roxithromycin suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 58 suppliers
30 of 30 offers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

58 suppliers in 14 countries

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Roxithromycin price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

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Uses and applications

What the substance is used for, by industry and function

Pharmacological actions

  • Anti-Bacterial Agents

Roles

  • antibacterial agent
  • antibacterial drug
  • antiinfective agent
  • antimicrobial agent
  • antimicrobial drug
  • environmental contaminant
  • pharmaceutical
  • xenobiotic

Pharmacology

Roxithromycin is a semi-synthetic derivative of the macrolide antibiotic erythromycin that includes an N-oxime side chain on the lactone ring, with antibacterial and anti-malarial activities. Roxithromycin binds to the subunit 50S of the bacterial ribosome, which inhibits bacterial protein synthesis and leads to inhibition of bacterial cell growth and replication.

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Roxithromycin is traded under.

HS 2941.50Indicative HS code

Erythromycin and its derivatives, salts thereof

World exports in 2024
$379M
−31.1% vs 2023, imports $408M
2019 to 2024
Top exporters
  1. China79.0%
  2. India * partner reported10.6%
  3. Malaysia1.7%
Top importers
  1. India * partner reported27.3%
  2. Japan9.9%
  3. Croatia6.3%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Roxithromycin is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Roxithromycin, based on the data on this page

What is Roxithromycin?

Roxithromycin is semisynthetic derivative of erythromycin A. It has a role as an antibacterial drug. It is a macrolide, an erythromycin derivative and a semisynthetic derivative. It is functionally related to an erythromycin A.

What is the CAS number of Roxithromycin?

The CAS registry number of Roxithromycin is 80214-83-1.

What is the molecular formula and weight of Roxithromycin?

The molecular formula of Roxithromycin is C41H76N2O15 and its molar mass is 837.06 g/mol.

What is Roxithromycin used for?

Known uses and roles of Roxithromycin include antibacterials and antibiotics in pharmaceuticals, antibacterial agent, antibacterial drug, antiinfective agent, antimicrobial agent and 5 more.

Is Roxithromycin hazardous?

Roxithromycin carries the GHS signal word "Warning". Main hazards: harmful if swallowed. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Roxithromycin?

Roxithromycin is usually classified under HS code 294150 (Erythromycin and its derivatives, salts thereof). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Roxithromycin?

CompoundList lists 58 suppliers of Roxithromycin in China, India, United States, Germany and 10 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Roxithromycin in India?

14 suppliers in India list Roxithromycin on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Roxithromycin?

Suppliers quote Roxithromycin on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Roxithromycin

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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