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Amino acids and derivatives

Sarcosine

Also known as N-methylglycine, 2-(methylamino)acetic acid, Sarcosinic acid

CAS 107-97-1Formula C3H7NO2Molar mass 89.09 g/molEC 203-538-6
120 suppliers listed
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Sarcosine chemical structure, C3H7NO2, CAS 107-97-1
2D chemical structure

Key facts

What buyers check first

All properties
Physical form
Crystals
Melting point
207.8 °C
Solubility
Greater than or equal to 100 mg/mL at 61 °F
HS code
292249
Category
Amino acids and derivatives
Illustrative photo, a shrink wrapped pallet of kraft paper sacks in a chemical plant
Typical packagingIllustrative packaging image, not the actual product

What is Sarcosine?

Plain description, key identifiers and synonyms

Sarcosine is a N-alkylglycine that is the N-methyl derivative of glycine. It is an intermediate in the metabolic pathway of glycine. It has a role as a glycine transporter 1 inhibitor, a glycine receptor agonist, a mouse metabolite, an Escherichia coli metabolite and a human metabolite. It is a N-methyl-amino acid, a member of N-methylglycines and a N-alkylglycine. It is a conjugate base of a sarcosinium. It is a conjugate acid of a sarcosinate. It is a tautomer of a sarcosine zwitterion.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
2-(methylamino)acetic acid
CAS number
107-97-1 CAS number cross-checkedOther or deprecated CAS: 25951-24-0
EC numbers
203-538-6, 270-156-4
Molecular formula
C3H7NO2
UNII
820Q60DZ0I, Z711V88R5F
MDL number
MFCD00004279
INCI name
COCOYL SARCOSINE, SARCOSINE
InChIKey
FSYKKLYZXJSNPZ-UHFFFAOYSA-N
InChI
InChI=1S/C3H7NO2/c1-4-2-3(5)6/h4H,2H2,1H3,(H,5,6)
SMILES (canonical and isomeric)
CNCC(=O)O

Synonyms

  • N-methylglycine
  • 2-(methylamino)acetic acid
  • Sarcosinic acid
  • Methylglycine
  • Glycine, N-methyl-
  • N-Methylaminoacetic acid
  • Methylaminoacetic acid
  • (Methylamino)acetic acid
  • Sarcosin
  • (Methylamino)ethanoic acid
  • Acetic acid, (methylamino)-
  • (methylamino)acetate
  • Methylaminoethanoic acid
  • N Methylglycine
  • Sarcosylate, Magnesium
  • Methyl glycocoll
  • 2-(methylazaniumyl)acetate
  • Sargosine hydrochloride
  • N-Methyl glycine
  • N-Methylglycocoll
  • N-methyl-Glycine
  • MeGly
  • N-Cocoyl-N-methylglycine
  • N-Cocoyl sarcosine
  • Me-Gly-OH
Show all 38 synonyms
  • (methylamino)-Acetate
  • SAR
  • Methylamino-Acetic Acid
  • CH3NHCH2COOH
  • 2-Methylaminoethanoic acid
  • Cocoylsarcosine
  • Cocoyl sarcosine
  • Cocobetaine
  • arcosine
  • methyl-glycine
  • Coco-betaine
  • L-sarcosine
  • N-Methyl-glycocoll

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Physical form
Crystalsexp.
Melting point
207.8 °Cexp.
Solubility
Greater than or equal to 100 mg/mL at 61 °Fexp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
89.09 g/molcalc.
Exact mass
89.0477 Dacalc.
LogP (octanol/water)
-0.71calc.
Topological polar surface area
49.33 Ųcalc.
Hydrogen bond donors
2calc.
Hydrogen bond acceptors
2calc.
Rotatable bonds
2calc.
Heavy atoms
6calc.
Rings
0calc.
Aromatic rings
0calc.
Fraction sp3 carbons
0.67calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Safety and hazards

GHS classification summary, not a safety data sheet

GHS classification
Hazard pictograms

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Sarcosine suppliers

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All 120 suppliers
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Where suppliers are based

120 suppliers in 15 countries

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Sarcosine price

Indicative price range per kg from live supplier offers

No published prices right now

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Uses and applications

What the substance is used for, by industry and function

Use classes: Cosmetics.

Cosmetic ingredient, INCI name SARCOSINE(skin conditioning)

Roles

  • Escherichia coli metabolite
  • agonist
  • animal metabolite
  • antidepressant
  • antipsychotic agent
  • bacterial metabolite
  • central nervous system depressant
  • central nervous system drug
  • eukaryotic metabolite
  • glycine receptor agonist
  • glycine transporter 1 inhibitor
  • glycine transporter inhibitor
  • human metabolite
  • mammalian metabolite
  • metabolite
  • mouse metabolite
  • pharmaceutical
  • prokaryotic metabolite
  • psychotropic drug
  • tranquilizing drug

Functional uses

  • Cleaning agent
  • Softener and conditioner
  • Surfactant (surface active agent)

Cosmetic functions

  • Cleansing
  • Hair conditioning
  • Skin conditioning
  • Surfactant - cleansing

Pharmacology

Sarcosine is an amino acid that is an intermediate and byproduct in glycine synthesis and degradation with potential anti-depressant and anti-schizophrenic activities. Sarcosine is a product of dietary consumption of choline and creatine and is rapidly converted into glycine. Oral administration of sarcosine with certain antipsychotics may cause increased glycine concentration in the brain, which may lead to increased NMDA receptor activation and a reduction in symptoms.

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • EU cosmetic ingredient inventory

United States

  • TSCA inventory (USA)
    Status: Active in US commerce

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Sarcosine is traded under.

HS 2922.49Indicative HS code

Amino-acids, other than those containing more than one kind of oxygen function, and…

World exports in 2024
$3.88B
−11.5% vs 2023, imports $3.87B
2019 to 2024
Top exporters
  1. China38.7%
  2. India * partner reported8.3%
  3. Germany8.1%
Top importers
  1. United States13.4%
  2. Germany11.1%
  3. Japan6.6%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Sarcosine is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Sarcosine, based on the data on this page

What is Sarcosine?

Sarcosine is a N-alkylglycine that is the N-methyl derivative of glycine. It is an intermediate in the metabolic pathway of glycine. It has a role as a glycine transporter 1 inhibitor, a glycine receptor agonist, a mouse metabolite, an Escherichia coli metabolite and a human metabolite.

What is the CAS number of Sarcosine?

The CAS registry number of Sarcosine is 107-97-1. Other or deprecated CAS numbers: 25951-24-0.

What is the molecular formula and weight of Sarcosine?

The molecular formula of Sarcosine is C3H7NO2 and its molar mass is 89.09 g/mol.

What is Sarcosine used for?

Use classes: Cosmetics.

Is Sarcosine hazardous?

No GHS hazard classification for Sarcosine is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Sarcosine?

Sarcosine is usually classified under HS code 292249 (Amino-acids, other than those containing more than one kind of oxygen function, and…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Sarcosine?

CompoundList lists 120 suppliers of Sarcosine in China, United States, Germany, India and 11 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Sarcosine in India?

6 suppliers in India list Sarcosine on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Sarcosine?

Suppliers quote Sarcosine on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Sarcosine

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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